Patents by Inventor Edouard Nice

Edouard Nice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Truncated EGF Receptor
    Publication number: 20090117134
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: October 20, 2008
    Publication date: May 7, 2009
    Applicants: Commonwealth Scientific and Industrial Research Organisation, Ludwig institute for Cancer Research
    Inventors: Colin Wesley WARD, Neil Moreton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Anthony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice
  • Methods of screening based on the EGF receptor crystal structure
    Publication number: 20080025983
    Abstract: This invention relates to the structure of members of the epidermal growth factor (EGF) receptor family and to receptor/ligand interactions. In particular, it relates to the field of using the EGF receptor family structure to select and screen for compounds that inhibit the formation of active receptor dimers.
    Type: Application
    Filed: August 3, 2007
    Publication date: January 31, 2008
    Inventors: Timothy Adams, Antony Burgess, Thomas Elleman, Thomas Garrett, Robert Jorissen, Meizhen Lou, George Lovrecz, Neil McKern, Edouard Nice, Colin Ward
  • Novel inhibitors and methods for their preparation
    Publication number: 20070099917
    Abstract: The present invention relates to novel tyrosine kinase (TK) inhibitors in the form of prodrugs.
    Type: Application
    Filed: October 6, 2006
    Publication date: May 3, 2007
    Applicant: THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
    Inventors: Edouard Nice, Antony Burgess, Keith Watson
  • Truncated EGF receptor
    Publication number: 20060234343
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: August 22, 2005
    Publication date: October 19, 2006
    Inventors: Colin Ward, Neil McKern, George Lovrecz, Robert Jorissen, Thomas Garrett, Thomas Elleman, Antony Burgess, Timothy Adams, Teresa Domagala, Edouard Nice
  • Truncated EGF receptor
    Patent number: 6946543
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF-?. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: September 20, 2005
    Assignees: Commonwealth Scientific and Industrial Research Organisation, Ludwig Institute for Cancer Research
    Inventors: Colin Wesley Ward, Neil Morton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Antony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice
  • Truncated egf receptor
    Publication number: 20030108953
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TNFI. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: October 10, 2002
    Publication date: June 12, 2003
    Inventors: Colin Wesley Ward, Neil Moreton McKern, George Oscar Lovrecz, Robert Nicholas Jorissen, Thomas Peter John Garrett, Thomas Charles Elleman, Anthony Wilkes Burgess, Timothy Edward Adams, Teresa Anne Domagala, Edouard Nice
  • Isolated nucleic acid which encodes protein which binds to A33 antibody
    Patent number: 6291235
    Abstract: This invention relates to isolated proteins and to peptides which are found on the surface of colon cells and colon cancer cells, as well as to nucleic acid molecules encoding said protein and peptides. The protein and peptides bind to tumor associated antibodies, such as mAb 33. The monomeric protein has a molecular weight of about 43 kD as determined by SDS gel electrophoresis under non-reducing conditions. In addition, this invention relates to the use of said nucleic acid molecules, protein, in monomeric or multimeric form, and to antibodies to said peptides in diagnostic, screening and therapeutic methods. This invention further relates to antibodies specific for said protein, in monomeric or multimeric form, and to antibodies to said peptides.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: September 18, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Sydney Welt, Sara White, Cameron Johnstone, Lloyd J Old, Gerd Ritter, Bruno Catimel, Hong Ji, Antony Burgess, Joan Heath, Richard J Simpson, Edouard Nice, R. L Moritz
  • Isolated protein which binds to A33 antibody, and peptides corresponding to portions of the protein
    Patent number: 5712369
    Abstract: This invention relates to isolated protein and to peptides which are found on the surface of colon cells and colon cancer cells, as well as to nucleic acid molecules encoding said protein and peptides. The protein and peptides bind to tumor-associated antibodies, such as mAb A33. The monomeric protein has a molecular weight of about 43 kD as determined by SDS gel electrophoresis under non-reducing conditions. In addition, this invention relates to the use of said nucleic acid molecules, protein, in monomeric or multimeric form, and to antibodies to said peptides in diagnostic, screening and therapeutic methods. This invention further relates to antibodies specific for said protein, in monomeric or multimeric form, and to antibodies to said peptides.
    Type: Grant
    Filed: February 2, 1996
    Date of Patent: January 27, 1998
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Lloyd J. Old, Sydney Welt, Gerd Ritter, Richard J. Simpson, Edouard Nice, R. L. Moritz, B. Catimel, Hong Ji, Anthony W. Burgess, Joan K. Heath, Sara J. White, Cameron Johnstone