Patents by Inventor Eduard Berenshtein

Eduard Berenshtein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METAL COMPLEXES OF NOCARDAMINE AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS
    Publication number: 20230181597
    Abstract: The present invention relates to complexes of nocardamine (desferrioxamine E) with at least one metal, specifically with Zn2+ or Ga3+ or silver or gold or any combinations thereof. The invention further provides procedures for the preparation of the complexes and pharmaceutical compositions comprising said complexes or any combinations of said complexes, as well as methods using the compositions and complexes of the invention in modulating cytokine levels in a subject and thereby treating inflammation-associated disorders.
    Type: Application
    Filed: December 22, 2022
    Publication date: June 15, 2023
    Inventors: Mordechai CHEVION, Vladimir VINOKUR, Ron ELIASHAR, Eduard BERENSHTEIN
  • Method and pharmaceutical composition for treatment of neurodegeneration
    Patent number: 11033630
    Abstract: The present invention provides pharmaceutical compositions comprising a metal-desferrioxamine B complex or a combination thereof, for preventing, inhibiting, reducing or ameliorating neurodegeneration, thereby treating diseases, disorders, or conditions characterized by or associated with neurodegeneration; as well as methods of use.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: June 15, 2021
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein
  • METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF NEURODEGENERATION
    Publication number: 20190358334
    Abstract: The present invention provides pharmaceutical compositions comprising a metal-desferrioxamine B complex or a combination thereof, for preventing, inhibiting, reducing or ameliorating neurodegeneration, thereby treating diseases, disorders, or conditions characterized by or associated with neurodegeneration; as well as methods of use.
    Type: Application
    Filed: February 8, 2017
    Publication date: November 28, 2019
    Inventors: Mordechai CHEVION, Vladimir VINOKUR, Eduard BERENSHTEIN
  • NEW METAL COMPLEXES OF NOCARDAMINE AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS
    Publication number: 20190022103
    Abstract: The present invention relates to complexes of nocardamine (desferrioxamine E) with at least one metal, specifically with Zn2+ or Ga3+ or silver or gold or any combinations thereof. The invention further provides procedures for the preparation of the complexes and pharmaceutical compositions comprising said complexes or any combinations of said complexes, as well as methods using the compositions and complexes of the invention in modulating cytokine levels in a subject and thereby treating inflammation-associated disorders.
    Type: Application
    Filed: December 22, 2015
    Publication date: January 24, 2019
    Inventors: Mordechai CHEVION, Vladimir VINOKUR, Ron ELIASHAR, Eduard BERENSHTEIN
  • DESFERRIOXAMINE-METAL COMPLEXES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS
    Publication number: 20150148413
    Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.
    Type: Application
    Filed: January 27, 2015
    Publication date: May 28, 2015
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein, Ron Eliashar, Baruch Bulvik
  • Desferrioxamine-metal complexes for the treatment of immune-related disorders
    Patent number: 8975294
    Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: March 10, 2015
    Assignees: Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein, Ron Eliashar, Baruch Bulvik
  • Metallo-desferrioxamine complexes and their use in the treatment of bacterial infections
    Patent number: 8680148
    Abstract: Methods for treating a bacterial infection by using a metallo-desferrioxamine complex.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: March 25, 2014
    Assignees: University of Washington, Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: E. Peter Greenberg, Ehud Banin, Eyal Banin, Eduard Berenshtein, Mordechai Chevion
  • DESFERRIOXAMINE-METAL COMPLEXES FOR THE TREATMENT OF IMMUNE-RELATED DISORDERS
    Publication number: 20120220651
    Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.
    Type: Application
    Filed: August 19, 2010
    Publication date: August 30, 2012
    Applicants: Hadasit Medical Research Services & Development Lt, Yissum Research Development Company of the Hebrew
    Inventors: Mordechai Chevion, Vladimir Vinokur, Eduard Berenshtein, Ron Eliashar, Baruch Bulvik
  • METALLO-DESFERRIOXAMINE COMPLEXES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20080085866
    Abstract: Methods for treating a bacterial infection by using a metallo-desferrioxamine complex.
    Type: Application
    Filed: August 13, 2007
    Publication date: April 10, 2008
    Applicants: WASHINGTON, UNIVERSITY OF, HADASSAH MEDICAL ORGANIZATION - HADASIT
    Inventors: E. Greenberg, Ehud Banin, Eyal Banin, Eduard Berenshtein, Mordechai Chevion