Patents by Inventor Eduard Denisov
Eduard Denisov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11842892Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.Type: GrantFiled: April 19, 2022Date of Patent: December 12, 2023Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Mikhail Belov, Eduard Denisov, Gregor Quiring, Dmitry Grinfeld
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Publication number: 20220238321Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.Type: ApplicationFiled: April 19, 2022Publication date: July 28, 2022Applicant: Thermo Fisher Scientific (Bremen) GmbHInventors: Mikhail BELOV, Eduard DENISOV, Gregor QUIRING, Dmitry GRINFELD
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Patent number: 11328922Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.Type: GrantFiled: May 22, 2017Date of Patent: May 10, 2022Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Mikhail Belov, Eduard Denisov, Gregor Quiring, Dmitry Grinfeld
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Patent number: 9865441Abstract: The present disclosure provides a mass spectrometer for performing an analysis of sample ions, and a method for operating a mass spectrometer. The mass spectrometer comprises a first ion optical element that is supplied with a first gas; a mass analyzer, wherein the performance of the mass analyzer is dependent on the pressure of the first gas in the first ion optical element; and a controller for setting a property of the first gas, which comprises at least the pressure of the first gas, on the basis of a characteristic of the analysis to be performed by the mass spectrometer.Type: GrantFiled: August 21, 2014Date of Patent: January 9, 2018Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Nicolaie Eugen Damoc, Eduard Denisov, Dirk Nolting, Martin Zeller
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Publication number: 20170352530Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.Type: ApplicationFiled: May 22, 2017Publication date: December 7, 2017Inventors: Mikhail BELOV, Eduard DENISOV, Gregor QUIRING, Dmitry GRINFELD
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Patent number: 9536722Abstract: An ion guide for mass spectrometry comprising an electrode arrangement of at least two electrodes, at least one of which is an RF electrode, arranged adjacent to each other but spaced apart on a planar surface of a dielectric material and arranged at a distance from an ion flow path, wherein a portion of the dielectric surface is exposed between an adjacent pair of the spaced apart electrodes and wherein at least one electrode of said adjacent pair of electrodes is arranged to overhang the exposed portion of surface between them such that there is no direct line of sight from the ion flow path to the exposed portion of dielectric surface. The device enables RF guiding of ions accompanied by much reduced charging-up of dielectric surfaces and reduced amount of collisions of neutral species with electrodes.Type: GrantFiled: September 19, 2013Date of Patent: January 3, 2017Assignee: Thermo Fisher Scientific (Bremen) GmbHInventors: Dmitry Grinfeld, Jan-Peter Hauschild, Wilko Balschun, Eduard Denisov, Alexander Makarov
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Publication number: 20160203964Abstract: The present disclosure provides a mass spectrometer for performing an analysis of sample ions, and a method for operating a mass spectrometer. The mass spectrometer comprises a first ion optical element that is supplied with a first gas; a mass analyzer, wherein the performance of the mass analyzer is dependent on the pressure of the first gas in the first ion optical element; and a controller for setting a property of the first gas, which comprises at least the pressure of the first gas, on the basis of a characteristic of the analysis to be performed by the mass spectrometer.Type: ApplicationFiled: August 21, 2014Publication date: July 14, 2016Inventors: Nicolaie Eugen DAMOC, Eduard DENISOV, Dirk NOLTING, Martin ZELLER
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Publication number: 20150228467Abstract: An ion guide for mass spectrometry comprising an electrode arrangement of at least two electrodes, at least one of which is an RF electrode, arranged adjacent to each other but spaced apart on a planar surface of a dielectric material and arranged at a distance from an ion flow path, wherein a portion of the dielectric surface is exposed between an adjacent pair of the spaced apart electrodes and wherein at least one electrode of said adjacent pair of electrodes is arranged to overhang the exposed portion of surface between them such that there is no direct line of sight from the ion flow path to the exposed portion of dielectric surface. The device enables RF guiding of ions accompanied by much reduced charging-up of dielectric surfaces and reduced amount of collisions of neutral species with electrodes.Type: ApplicationFiled: September 19, 2013Publication date: August 13, 2015Inventors: Dmitry Grinfeld, Jan-Peter Hauschild, Wilko Balschun, Eduard Denisov, Alexander Makarov
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Publication number: 20080048112Abstract: The present invention provides a radio frequency (RF) power supply in a mass spectrometer. The power supply provides an RF signal to electrodes of a storage device to create a trapping field. Such ion storage devices are often used to store ions prior to ejection to a subsequent mass analyser. The RF field is usually collapsed prior to ion ejection. The present invention provides a RF power supply comprising: a RF signal supply, a coil arranged to receive the signal provided by the RF signal supply and to provide an output RF signal for supply to electrodes of an ion storage device, and a shunt including a switch operative to switch between a first open position and a second closed position in which the shunt including a switch operative to switch between a first open position and a second closed position in which the shunt shorts the coil output.Type: ApplicationFiled: June 21, 2005Publication date: February 28, 2008Applicant: Thermo Finnigan LLCInventors: Alexander Makarov, Eduard Denisov, Alexander Kholomeev
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Publication number: 20070138386Abstract: The present invention relates to a method and apparatus for ion fragmentation by electron capture. The present invention provides a method of generating fragment ions by electron capture, comprising; directing ions to be fragmented into a fragmentation chamber of a mass spectrometer into a fragmentation chamber of a mass spectrometer arrangement; trapping at least some of the ions to be fragmented in at least one direction of the fragmentation chamber by using a magnetic field, the ions being trapped within a volume V; generating an electron beam using an electron source located away from the volume V; irradiating the trapped ions in the volume V with the electrons generated by the electron source in the presence of the said magnetic field, so as to cause dissociation; and ejecting the resultant fragment ions from the fragmentation chamber for subsequent analysis at a different location away from the fragmentation chamber.Type: ApplicationFiled: March 29, 2005Publication date: June 21, 2007Inventors: Alexander Makarov, Eduard Denisov, Gerhard Jung