Patents by Inventor Eduard Stange

Eduard Stange has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210371483
    Abstract: A composition, which comprises at least one natural, recombinant, or synthetic human antimicrobial peptide, is selected from a human defensin or cathelicidin or functional fragments or combinations thereof, for inactivating bacterial spores.
    Type: Application
    Filed: October 6, 2017
    Publication date: December 2, 2021
    Inventors: Sabine Nuding, Eduard Stange
  • Publication number: 20170073371
    Abstract: A novel antimicrobial peptide includes at least eight successive amino acids, the peptide exhibiting a sequence having the following formula: Ter1-X1—B1—X2—B2—X3—Z1—Z2—X4-Ter2. The peptide can moreover also have modified termini. The peptide is believed to be effective for the treatment or prevention of inflammatory and infectious diseases that are caused by microorganisms such as bacteria or fungi.
    Type: Application
    Filed: November 23, 2016
    Publication date: March 16, 2017
    Inventors: Eduard STANGE, Bjoern SCHROEDER, Jan WEHKAMP
  • Publication number: 20150087579
    Abstract: A novel antimicrobial peptide includes at least eight successive amino acids, the peptide exhibiting a sequence having the following formula: Ter1-X1-B1-X2-B2-X3-Z1-Z2-X4-Ter2. The peptide can moreover also have modified termini. The peptide is believed to be effective for the treatment or prevention of inflammatory and infectious diseases that are caused by microorganisms such as bacteria or fungi.
    Type: Application
    Filed: March 7, 2013
    Publication date: March 26, 2015
    Applicant: ROBERT BOSCH GENSELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG MBH
    Inventors: Eduard Stange, Bjoern Schroeder, Jan Wehkamp
  • Publication number: 20130336950
    Abstract: A material combination is configured to treat or prevent inflammatory and infectious diseases caused by fastidious anaerobic or facultative anaerobic microorganisms, such as bacteria or Candida sp. The material combination includes at least one antimicrobial peptide that can be activated by a reducing substance, and at least one reducing agent.
    Type: Application
    Filed: August 19, 2011
    Publication date: December 19, 2013
    Inventors: Jan Wehkamp, Bjoern Schroeder, Eduard Stange
  • Publication number: 20110319284
    Abstract: A method is described for determining a predisposition of an organism for Crohn's Disease, especially Crohn's Disease of the small intestine. In this context, in a biological specimen of an organism, the presence or the absence of SNP's in at least one gene is determined, which codes for a protein associated with the Writ signaling pathway in Paneth cells. The gene, in this instance, may be selected from TCF4, LRP5, LRP6, GSK3A, GSK3B and TCF7. The present methods and systems also relate to primers and allele-specific probes to prove the presence or the absence of an SNP, diagnostic kits which have at least one such primer or one such allele-specific probe, as well as the use of certain SNP's for determining a predisposition of an organism for Crohn's Disease. The present method and systems also relate to a method for the differential diagnosis of inflammatory bowel diseases, for distinguishing Crohn's Disease and the other respective inflammatory or infectious intestinal diseases.
    Type: Application
    Filed: December 21, 2009
    Publication date: December 29, 2011
    Inventors: Jan Wehkamp, Eduard Stange, Maureen Koslowski