Patents by Inventor Eduarde ROHNER

Eduarde ROHNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of osteoarthritis and/or rheumatoid arthritis with pro-chondrogenic and/or chondrocyte protective factors
    Publication number: 20260021143
    Abstract: The present disclosure relates to mesenchymal stem cells (MSCs) for use in a method of treatment of arthritis. The MSCs are transfected with an mRNA construct encoding a pro-chondrogenic and/or chondrocyte protective factor. The pro-chondrogenic and/or chondrocyte protective factor can be TGF?3.
    Type: Application
    Filed: July 17, 2025
    Publication date: January 22, 2026
    Inventors: Ran YANG, Kylie Foo, Eduarde Rohner
  • Treatment of osteoarthritis and/or rheumatoid arthritis with pro-chondrogenic and/or chondrocyte protective factors
    Publication number: 20250352583
    Abstract: The present disclosure relates to mesenchymal stem cells (MSCs) for use in a method of treatment of arthritis. The MSCs are transfected with an mRNA construct encoding a pro-chondrogenic and/or chondrocyte protective factor. The pro-chondrogenic and/or chondrocyte protective factor can be WNT3a.
    Type: Application
    Filed: July 17, 2025
    Publication date: November 20, 2025
    Inventors: Ran YANG, Kylie Foo, Eduarde Rohner
  • COMPOSITIONS AND METHODS FOR EXOSOME-MEDIATED DELIVERY OF mRNA AGENTS
    Publication number: 20230330264
    Abstract: Compositions and methods for delivery of mRNA agents to subjects are provided in which the mRNA agents are encapsulated in exosomes prepared from human stem cells or progenitor cells, such as human mesenchymal stem cells, human embryonic stem cells or human cardiac progenitor cells. The compositions and methods can be used for delivery of mRNA agents encoding therapeutics, such as enzymes (e.g., metabolic enzymes), cytokines, growth factors, antigens, antibodies or immunomodulatory agents, by administering the compositions to the subject. Methods of preparing compositions comprising exosomes encapsulating mRNA agents are also provided.
    Type: Application
    Filed: April 13, 2023
    Publication date: October 19, 2023
    Inventors: Kenneth CHIEN, John Paul SCHELL, Ran YANG, Eduarde ROHNER, Anna MARIANI, Jesper SOHLMÉR, Kylie FOO, Nevin WITMAN