Patents by Inventor Eduardo Gustavo Cammisa

Eduardo Gustavo Cammisa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for the preparation of Tezacaftor and intermediates thereof
    Patent number: 10875846
    Abstract: The present invention provides processes for the preparation of Tezacaftor, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the preparation of a compound of Formula (3), and its conversion to Tezacaftor (1).
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: December 29, 2020
    Assignee: Apotex Inc.
    Inventors: Michael R. Emmett, Prabhudas Bodhuri, Yajun Zhao, Eduardo Gustavo Cammisa, Stuart P. Green
  • Processes for the Preparation of Tezacaftor and Intermediates Thereof
    Publication number: 20200223832
    Abstract: The present invention provides processes for the preparation of Tezacaftor, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the preparation of a compound of Formula (3), and its conversion to Tezacaftor (1).
    Type: Application
    Filed: January 13, 2020
    Publication date: July 16, 2020
    Inventors: Michael R. Emmett, Prabhudas Bodhuri, Yajun Zhao, Eduardo Gustavo Cammisa, Stuart P. Green
  • Processes for the Preparation of Dasotraline and Intermediates Thereof
    Publication number: 20190390235
    Abstract: The present invention provides processes for the preparation of Dasotraline, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the enzymatic transamination of a compound of Formula (2) to afford Dasotraline.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 26, 2019
    Inventors: Fabio E. S. Souza, Prabhudas Bodhuri, Eduardo Gustavo Cammisa, Gamini Weeratunga, Allan W. Rey
  • Processes for the Preparation of Dasotraline and Intermediates Thereof
    Publication number: 20190194122
    Abstract: The present invention provides processes for the preparation of Dasotraline (1), as well as intermediates useful in the preparation thereof. In particular, processes are provided for the production of the compound of Formula (2), or a salt thereof, and its deprotection to afford Dasotraline (1).
    Type: Application
    Filed: December 18, 2018
    Publication date: June 27, 2019
    Inventors: Prabhudas Bodhuri, Eduardo Gustavo Cammisa, Melanie R.A. Green, Gamini Weeratunga, Boris Gorin
  • Processes for the preparation of edoxaban and intermediates thereof
    Patent number: 10301322
    Abstract: The present invention provides processes for the preparation of Edoxaban (1) and salts thereof, as well as intermediates thereof. In particular, intermediate compounds and/or salts of the Formulae (3), (4), (6-A), (7-A), (8-A), (9-A) and (10-AS) are provided.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: May 28, 2019
    Assignee: Apotex Inc.
    Inventors: Prabhudas Bodhuri, Avedis Karadeolian, Eduardo Gustavo Cammisa, Stuart P. Green, Melanie R. A. Green, Alfredo Paul Ceccarelli
  • Processes for the Preparation of Edoxaban and Intermediates Thereof
    Publication number: 20180179226
    Abstract: The present invention provides processes for the preparation of Edoxaban (1) and salts thereof, as well as intermediates thereof. In particular, intermediate compounds and/or salts of the Formulae (3), (4), (6-A), (7-A), (8-A), (9-A) and (10-AS) are provided.
    Type: Application
    Filed: December 21, 2017
    Publication date: June 28, 2018
    Inventors: Prabhudas Bodhuri, Avedis Karadeolian, Eduardo Gustavo Cammisa, Stuart P. Green, Melanie R. A. Green, Alfredo Paul Ceccarelli
  • Solid forms of tofacitinib salts
    Patent number: 9260438
    Abstract: Solid and crystalline forms of tofacitinib hydrochloride and tofacitinib hydrobromide, processes for the preparation thereof and processes for the use thereof in preparing tofacitinib citrate are provided.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: February 16, 2016
    Assignee: Apotex Inc.
    Inventors: Prabhudas Bodhuri, Stuart P. Green, Fan Wang, Cameron L. McPhail, Eduardo Gustavo Cammisa, Avedis Karadeolian
  • SOLID FORMS OF TOFACITINIB SALTS
    Publication number: 20150225406
    Abstract: Solid and crystalline forms of tofacitinib hydrochloride and tofacitinib hydrobromide, processes for the preparation thereof and processes for the use thereof in preparing tofacitinib citrate are provided.
    Type: Application
    Filed: February 6, 2015
    Publication date: August 13, 2015
    Inventors: Prabhudas Bodhuri, Stuart P. Green, Fan Wang, Cameron L. McPhail, Eduardo Gustavo Cammisa, Avedis Karadeolian
  • Polymorphic forms of Lapatinib ditosylate and processes for their preparation
    Patent number: 8993579
    Abstract: There is provided a crystalline form of Lapatinib, termed APO-I, and methods for making APO-I. There is also provided a crystalline solvate form of Lapatinib, termed APO-II, and methods for making APO-II.
    Type: Grant
    Filed: April 21, 2011
    Date of Patent: March 31, 2015
    Assignee: Apotex Pharmachem Inc
    Inventors: Carlos Zetina-Rocha, Eduardo Gustavo Cammisa, Gamini Weeratunga
  • Process for the preparation of lapatinib and its ditosylate salt
    Patent number: 8952154
    Abstract: There is provided processes for preparing Lapatinib and pharmaceutically acceptable salts thereof by the reductive amination of the aldehyde of Formula II by treatment with 2-methanesulphonylethylamine followed by catalytic hydrogenation in the presence of a suitable hydrogenation catalyst.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: February 10, 2015
    Assignee: Apotex Pharmachem Inc.
    Inventors: Mohammed Abdul Raheem, Gamini Weeratunga, Carlos Zetina-Rocha, Eduardo Gustavo Cammisa
  • PROCESS FOR THE PREPARATION OF LAPATINIB AND ITS DITOSYLATE SALT
    Publication number: 20140018535
    Abstract: There is provided processes for preparing Lapatinib and pharmaceutically acceptable salts thereof by the reductive amination of the aldehyde of Formula II by treatment with 2-methanesulphonylethylamine followed by catalytic hydrogenation in the presence of a suitable hydrogenation catalyst.
    Type: Application
    Filed: December 23, 2011
    Publication date: January 16, 2014
    Applicant: APOTEX PHARMACHEM INC.
    Inventors: Mohammed Abdul Raheem, Gamini Weeratunga, Carlos Zetina-Rocha, Eduardo Gustavo Cammisa
  • POLYMORPHIC FORMS OF LAPATINIB DITOSYLATE AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20130123497
    Abstract: There is provided a crystalline form of Lapatinib, termed APO-I, and methods for making APO-I. There is also provided a crystalline solvate form of Lapatinib, termed APO-II, and methods for making APO-II.
    Type: Application
    Filed: April 21, 2011
    Publication date: May 16, 2013
    Applicant: APOTEX PHARMACHEM INC.
    Inventors: Carlos Zetina-Rocha, Eduardo Gustavo Cammisa, Gamini Weeratunga