Abstract: Systems and methods for data-compressive sensing in accordance with embodiments of the invention are illustrated. In one embodiment, a sensor array includes an array of sensor circuitries including a sensor and a comparator. Sensor circuitries in the array are connected via wires which form a series of wired-OR circuits. Readouts can be used to measure the signal on the wires and a decoder in communication with the readouts can be used to resolve signals sensed by particular sensors in the array and their locations.

Abstract: Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses.

Abstract: Systems and methods for calibration of retinal prosthetics in accordance with embodiments of the invention are illustrated. A closed loop calibration process is described whereby a multi-electrode stimulation regime can be calibrated to a given user's retina. Multi-electrode stimulation can provide increased stimulation selectivity, but significantly increases complexity. Systems and methods described herein provide computational steps that significantly reduce the amount of trials and computation required in order to achieve clinically viable selectivity, making closed-loop calibration of retinal prosthetics possible in significantly less time than open-loop calibration.

Abstract: A retina clip in accordance with embodiments of the invention are illustrated. One embodiment includes a retina clip including an outer ring having a means of retention against the retina, and an inner platform configured to hold a payload against the retina of an eye, where the inner platform is suspended from the inner ring via several springs. In many embodiments, the springs are flexures. The springs can be modified to generate a desired deflection based on a given payload attached to the inner platform. In numerous embodiments, the payload is a microelectrode array used as part of a retinal prosthetic.

Abstract: Systems and methods for data-compressive sensing in accordance with embodiments of the invention are illustrated. In one embodiment, a sensor array includes an array of sensor circuitries including a sensor and a comparator. Sensor circuitries in the array are connected via wires which form a series of wired-OR circuits. Readouts can be used to measure the signal on the wires and a decoder in communication with the readouts can be used to resolve signals sensed by particular sensors in the array and their locations.

Abstract: Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses.

Abstract: Systems and methods for data-compressive sensing in accordance with embodiments of the invention are illustrated. In one embodiment, a sensor array includes an array of sensor circuitries including a sensor and a comparator. Sensor circuitries in the array are connected via wires which form a series of wired-OR circuits. Readouts can be used to measure the signal on the wires and a decoder in communication with the readouts can be used to resolve signals sensed by particular sensors in the array and their locations.

Abstract: A method of providing artificial vision to a visually-impaired user implanted with a visual prosthesis. The method includes configuring, in response to selection information received from the user, a smart prosthesis to perform at least one function of a plurality of functions in order to facilitate performance of a visual task. The method further includes extracting, from an input image signal generated in response to optical input representative of a scene, item information relating to at least one item within the scene relevant to the visual task. The smart prosthesis then generates image data corresponding to an abstract representation of the scene wherein the abstract representation includes a representation of the at least one item. Pixel information based upon the image data is then provided to the visual prosthesis.

Abstract: Retinal prostheses are configured to apply retinal stimulus signals based on retinal cell classification such as cell types or cell clusters identified based on retinal cell signals. Cell types are identified based on spontaneous or induced retinal electrical signals and analyzed based on temporal patterns of electrical activity, spatio-temporal voltage waveforms, and signal correlations that can be obtained from temporal spike patterns. Cell type indications are stored, and a signals are applied to the retina based on the stored cell type indications.

Abstract: A method of providing artificial vision to a visually-impaired user implanted with a visual prosthesis. The method includes configuring, in response to selection information received from the user, a smart prosthesis to perform at least one function of a plurality of functions in order to facilitate performance of a visual task. The method further includes extracting, from an input image signal generated in response to optical input representative of a scene, item information relating to at least one item within the scene relevant to the visual task. The smart prosthesis then generates image data corresponding to an abstract representation of the scene wherein the abstract representation includes a representation of the at least one item. Pixel information based upon the image data is then provided to the visual prosthesis.

Abstract: Retinal prostheses are configured to apply retinal stimulus signals based on retinal cell classification such as cell types or cell clusters identified based on retinal cell signals. Cell types are identified based on spontaneous or induced retinal electrical signals and analyzed based on temporal patterns of electrical activity, spatio-temporal voltage waveforms, and signal correlations that can be obtained from temporal spike patterns. Cell type indications are stored, and a signals are applied to the retina based on the stored cell type indications.

Abstract: A method and apparatus for applying electrical signals in specific spatial patterns to selectively activate sensory cells. The method comprises interfacing a population of cells with two or more electrodes, identifying target cells within the population to activate by electrical signals; and applying electrical signals in a spatial pattern to the population via the electrodes, such that the target cells are selectively activated in the desired spatial pattern.