Abstract: The present invention relates to novel cannabidiol quinone derivatives of formula (I) (I) wherein R is the carbon atom of a, linear or branched group, represented by: alkyl, aryl, alkenyl, alkynyl, acyl or alkoxycarbonyl groups; or wherein R is the nitrogen atom of a, linear or branched group represented by: alkylamine, arylamine, alkenylamine or alkynylamine groups. The invention also relates to the use of any of the compounds of formula (I) as medicaments in therapy, particularly for treating diseases and conditions responsive to PPARg modulation due to their high PPARg agonistic effect lacking electrophilic (Nrf2 activation) and cytotoxic activities. This invention also provides pharmaceutical compositions comprising said compounds and method of treating diseases with said compounds.

Abstract: The present invention relates to novel cannabidiol quinone derivatives of formula (I) (I) wherein R is the carbon atom of a, linear or branched group, represented by: alkyl, aryl, alkenyl, alkynyl, acyl or alkoxycarbonyl groups; or wherein R is the nitrogen atom of a, linear or branched group represented by: alkylamine, arylamine, alkenylamine or alkynylamine groups. The invention also relates to the use of any of the compounds of formula (I) as medicamentsin therapy, particularly for treating diseases and conditions responsive to PPARg modulation due to their high PPARg agonistic effect lacking electrophilic (Nrf2 activation) and cytotoxic activities. This invention also provides pharmaceutical compositions comprising said compounds and method of treating diseases with said compounds.

Abstract: The present invention relates to a new method for isolating ingenol (C20H28O5) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.

Abstract: Direct connection between a tube and a flat element by means of a connector preferably formed by stamping on the tube itself, which enables joining the latter to the flat element, without auxiliary elements, by nest-like insertion of same into the flat element and subsequent attachment by means of screws, rivets, bolts, pins or other elements.

Abstract: The present invention relates to a new method for isolating ingenol (C20H28O5) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.

Abstract: The present invention discloses novel compounds useful for the inhibition of IL-6/STAT signaling and/or PI3K/NF-?B signaling in the treatment of associated diseases or conditions, e.g. cancer. A pharmaceutical composition comprising such novel compounds, its use and a method thereof, is also disclosed.

Abstract: The present invention relates to a thermally-resistant woven fabric and/or multiple ply fabric sheet for use as single or outer layer of protective garments, of the type comprising an inside fabric layer and an outside fabric layer joined together by an array of connecting lines. The woven fabric and/or multiple ply fabric sheet comprise yarns, wherein said yarn comprises i) meta-aramid ii) from about 5 to 10 weight % of polyamide and iii) at least 2 weight % of antistatic fibers, the weight % being based on the total weight of the yarn.

Abstract: The present invention relates to a new method for isolating ingenol (C20H28O5) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.

Abstract: Cannabinoid quinone derivatives. The present invention refers to cannabinoid quinone derivatives to be used as medicaments, particularly as PPAR gamma (PPARg) agonists for treating diseases which etiology is based on an impaired PPARg function as transcription factor i.e. PPARg-related diseases.

Abstract: The present invention discloses novel compounds useful for the inhibition of IL-6/STAT signaling and/or PI3K/NF-?B signaling in the treatment of associated diseases or conditions, e.g. cancer. A pharmaceutical composition comprising such novel compounds, its use and a method thereof, is also disclosed.

Abstract: The invention relates to a direct connection between a tube and a flat element by means of a connector preferably formed by stamping on the tube itself, which enables joining the latter to the flat element, without auxiliary elements, by nest-like insertion of same into the flat element and subsequent attachment by means of screws, rivets, bolts, pins or other elements. Said connection can be used in the construction of modular two-dimensional or three-dimensional tubular structures forming a single, double, or multi-layer latticework, preferably for supporting parabolic trough solar collectors.

Abstract: Cannabinoid quinone derivatives. The present invention refers to cannabinoid quinone derivatives to be used as medicaments, particularly as PPAR gamma (PPARg) agonists for treating diseases which etiology is based on an impaired PPARg function as transcription factor i.e. PPARg-related diseases.

Abstract: A management server acts as a repository for a plurality of user certificates corresponding to a plurality of users. When a user wishes to access a remote computer such as a secure-enabled host requiring a secure credential, his/her computer sends a request message to the management server. The management server may perform its own validity checking. In response to a request and conditioned on the management server authorizing access to a computing resource that requires an authorization credential, the management server delivers the requested credential and executable code, the authorization credential comprising information that enables access to the computing resource and the delivered executable code manages the lifecycle of the delivered authorization credential by allowing only temporary storage without caching of the delivered authorization credential.

Abstract: A surface functional electro-textile fabric incorporates energy-active, electrically conductive or optically conductive fibers and nonconductive fibers in a woven or knitted textile fabric. The weave or knit pattern is selected so as to form floats of the electrically conductive fibers on at least one surface of the electro-textile fabric. The electro-textile fabric can be incorporated into an antenna structure that interacts with high frequency electromagnetic radiation, particularly in the frequency range of DC to 100 GHz.

Abstract: The invention relates to a composition comprising cannabidiol and Denbinobin and its use in medicine, for example, for the prevention and treatment of gastrointestinal inflammatory diseases and for the prevention and treatment of gastrointestinal cancers.

Abstract: A surface functional electro-textile fabric incorporates energy-active, electrically conductive or optically conductive fibers and nonconductive fibers in a woven or knitted textile fabric. The weave or knit pattern is selected so as to form floats of the electrically conductive fibers on at least one surface of the electro-textile fabric. The electro-textile fabric can be incorporated into an antenna structure that interacts with high frequency electromagnetic radiation, particularly in the frequency range of DC to 100 GHz.

Abstract: A surface functional electro-textile fabric incorporates energy-active, electrically conductive or optically conductive fibers and nonconductive fibers in a woven or knitted textile fabric. The weave or knit pattern is selected so as to form floats of the electrically conductive fibers on at least one surface of the electro-textile fabric. The electro-textile fabric can be incorporated into an antenna structure that interacts with high frequency electromagnetic radiation, particularly in the frequency range of DC to 100 GHz.