Patents by Inventor Eduardo Pirotzky

Eduardo Pirotzky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense oligonucleotides for inhibiting helicobacter pylori activity
    Patent number: 5977340
    Abstract: Antisense oligonucleotides that selectively hybridise with one or more genes necessary for Helicobacter pylori (H. pylori) activity, and particularly with the CagA cytotoxicity-associated immunodominant antigen, flagellin (flaA and flaB) or vacuolating cytotoxin (vacA), are disclosed. Pharmaceutical compositions containing said antisense oligonucleotides, and the use thereof for treating atrophic gastritis, peptic and duodenal ulcers, gastric atrophy or stomach cancer, are also disclosed.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: November 2, 1999
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Eduardo Pirotzky, Soudhir Colote
  • Anti sense oligonucleotides for blocking IgE receptor synthesis
    Patent number: 5892023
    Abstract: The invention is drawn to antisense oligonucleotides directed to the inhibition of the IgE receptor synthesis.
    Type: Grant
    Filed: November 20, 1997
    Date of Patent: April 6, 1999
    Assignee: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Eduardo Pirotzky, Soudhir Colote
  • Oligonucleotides to inhibit the expression of isoprenyl protein transferases
    Patent number: 5856461
    Abstract: The invention relates to oligonucleotides and their derivatives to inhibit the expression of isoprenyl protein transferases, therapeutic compositions containing such compounds and the use of such compositions of oligonucleotides for the treatment or therapy of diseases of the human or animal body induced by an abnormal and/or uncontrolled cellular proliferation.
    Type: Grant
    Filed: June 23, 1995
    Date of Patent: January 5, 1999
    Assignee: Societe De Conseils De Recherches Et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Soudhir Colote, Eduardo Pirotzky
  • 2-substituted N,N'-ditrimethoxybenzoyl piperazines and therapeutic compositions containing them
    Patent number: 5019576
    Abstract: This invention relates to piperazine derivatives of the general formula I ##STR1## wherein --(CH.sub.2).sub.n -- represents a straight or branched chain alkyl group having from n=1 to n=20 carbon atoms, and R represents a hydrogen atom, a branched alkyl group, a cycloalkyl group having from 5 to 10 carbon atoms, a phenyl group, optionally substituted by one or several chlorine atoms, methyl or methoxy groups, or straight or branched chain alkenyl groups having from 3 to 11 carbon atoms, to a preparation process of said compounds and to therapeutic compositions containing them as an active ingredient.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: May 28, 1991
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Pierre Braquet, Eduardo Pirotzky, Jean-Jacques Godfroid, Francoise Heymans
  • 2-methoxycarbonyl substituted N,N'-di-(trimethoxybenzoyl) piperazines, process for preparing the same and therapeutical compounds containing them
    Patent number: 4927825
    Abstract: This invention relates to piperazine derivatives having the general formula I: ##STR1## wherein Y stands for ##STR2## and Z represents various substituents, to a preparation process of said compounds and to therapeutic compositions containing them as an active ingredient.
    Type: Grant
    Filed: October 6, 1989
    Date of Patent: May 22, 1990
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Eduardo Pirotzky, Georges Dive, Jean-Jacques Godfroid, Francoise Heymans
  • 2-Carbonyl substituted N,N'-di-(trimethoxygenzoyl)piperazines, process for preparing the same and therapeutical compounds containing them
    Patent number: 4923870
    Abstract: This invention relates to piperazine derivatives having the general formula I: ##STR1## wherein Y stands for ##STR2## and Z represents various substituents, to be a preparation process of said compounds and to therapeutic compositions containing them as an active ingredient.
    Type: Grant
    Filed: October 6, 1989
    Date of Patent: May 8, 1990
    Assignee: Societe de Conseils de Reserches et d'Applications Scientifiques
    Inventors: Pierre Braquet, Georges Dive, Jean-Jacques Godfroid, Francoise Heymans, Eduardo Pirotzky