Patents by Inventor Edward A. Berger

Edward A. Berger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytotoxic agent against specific virus infection
    Patent number: 5587455
    Abstract: A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
    Type: Grant
    Filed: November 8, 1994
    Date of Patent: December 24, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Edward A. Berger, Bernard Moss, Thomas R. Fuerst, Ira Pastan, David Fitzgerald, Tamio Mizukami, Vijay K. Chaudhary
  • Cytotoxic agent against specific virus infection
    Patent number: 5428143
    Abstract: A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: June 27, 1995
    Assignee: United States of America
    Inventors: Edward A. Berger, Bernard Moss, Thomas R. Fuerst, Ira Pastan, David Fitzgerald, Tamio Mizukami, Vijay K. Chaudhary
  • CD-4/cytotoxic gene fusions
    Patent number: 5206353
    Abstract: A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.
    Type: Grant
    Filed: July 22, 1988
    Date of Patent: April 27, 1993
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Edward A. Berger, Bernard Moss, Thomas R. Fuerst, Ira Pastan, David Fitzgerald, Tamio Mizukami, Vijay K. Chaudhary