Abstract: The invention relates to the methods for identifying resistance to cancer therapy, by identification of an E63K NRAS mutation, a G12V NRAS mutation or a gain of copy number of NRAS gene. A further aspect of the invention relates to methods of treatment that may overcome such resistance mechanisms, involving the use of an EGFR inhibitor in combination with a MEK inhibitor for the treatment of cancers involving an NRAS mutation selected from E63K, G12V, G12R, G12A, G12D, G12S and G12C, and/or cancer involving a gain of copy number of NRAS gene.

Abstract: A system for deploying a first object for capturing, immobilising or disabling a second object is provided. The system comprises the first object, a projectile for carrying the first object therein, and a launcher for launching the projectile towards the second object, wherein the projectile is configured for deploying the first object in the vicinity of the second object for capturing, immobilising or disabling the second object.

Abstract: The invention relates to the methods for identifying resistance to cancer therapy, by identification of an E63K NRAS mutation, a G12V NRAS mutation or a gain of copy number of NRAS gene. A further aspect of the invention relates to methods of treatment that may overcome such resistance mechanisms, involving the use of an EGFR inhibitor in combination with a MEK inhibitor for the treatment of cancers involving an NRAS mutation selected from E63K, G12V, G12R, G12A, G12D, G12S and G12C, and/or cancer involving a gain of copy number of NRAS gene.

Abstract: A system for inhibiting the electronic system of a target object is provided. The system comprises an Electronic Counter Measure (ECM) unit, and a projectile for carrying the ECM unit towards the target object.

Abstract: A multiple position convertible seat assembly for a boat includes three seat frames pivotally coupled to the boat and to each other to move from a first position as a seat, a second position as a lounge seat with leg support, and a third position forming another seat. In the third position, the seat includes a foldout cushion exposing a work surface.

Abstract: A method for acquiring a remote object is provided. The method comprises obtaining a sequence of position samples of the remote object, identifying one or more sets of spatially clustered position samples from among the obtained position samples, and applying curve-fitting to at least one set of spatially clustered position samples to obtain a trajectory of the set of spatially clustered position samples. Also provided is a method for tracking a remote object. The method comprising obtaining an estimated trajectory of the object, obtaining one or more position samples of the object, comparing the obtained position samples with positions computed based on the estimated trajectory, and determining that the object is being tracked based on whether the obtained position samples are consistent with the computed positions.

Abstract: A multiple position convertible seat assembly for a boat includes three seat frames pivotally coupled to the boat and to each other to move from a first position as a seat, a second position as a lounge seat with leg support, and a third position forming another seat. In the third position, the seat includes a foldout cushion exposing a work surface.

Abstract: A system for inhibiting the electronic system of a target object is provided. The system comprises an Electronic Counter Measure (ECM) unit, and a projectile for carrying the ECM unit towards the target object.

Abstract: A multiple position convertible seat assembly for a boat includes three seat frames pivotally coupled to the boat and to each other to move from a first position as a seat, a second position as a lounge seat with leg support, and a third position forming another seat. In the third position, the seat includes a foldout cushion exposing a work surface.

Abstract: A process for recycling aqueous quenching fluids, said process comprising: (a)(1) providing a metal quenching bath tank comprising a used metal aqueous quenching fluid containing contamination with a water insoluble, fire resistant hydraulic fluid; or (a)(2) collecting, in a collection tank in association with a quench barrel or quench ring, used metal aqueous quenching fluid after the fluid has been sprayed onto heated metal, wherein the collected used fluid is contaminated with a water insoluble, fire resistant hydraulic fluid; (b) heating the bath tank (a)(1) or collection tank (a)(2) to a temperature of about 105 to 200 ° F. with agitation for less than 12 hours; (c) recovering a resulting uncontaminated aqueous quenching phase from a lower portion of the bath tank (a)(1) or collection tank (a)(2); and (d) returning the recovered aqueous quenching phase to a functional quenching bath tank or functional quenching spray tank.

Abstract: A method for acquiring a remote object is provided. The method comprises obtaining a sequence of position samples of the remote object, identifying one or more sets of spatially clustered position samples from among the obtained position samples, and applying curve-fitting to at least one set of spatially clustered position samples to obtain a trajectory of the set of spatially clustered position samples. Also provided is a method for tracking a remote object. The method comprising obtaining an estimated trajectory of the object, obtaining one or more position samples of the object, comparing the obtained position samples with positions computed based on the estimated trajectory, and determining that the object is being tracked based on whether the obtained position samples are consistent with the computed positions.

Abstract: A system for deploying a first object for capturing, immobilising or disabling a second object is provided. The system comprises the first object, a projectile for carrying the first object therein,and a launcher for launching the projectile towards the second object,wherein the projectile is configured for deploying the first object in the vicinity of the second object for capturing, immobilising or disabling the second object.

Abstract: A navigation system includes an improved interface for accessing points of interest. Popular chains and franchises are accessible via a separate search, which can be accessed more efficiently and quickly. The list of popular chains can then be used to access the main database of points of interest.

Abstract: A multiple position convertible seat assembly for a boat includes three seat frames pivotally coupled to the boat and to each other to move from a first position as a seat, a second position as a lounge seat with leg support, and a third position forming another seat. In the third position, the seat includes a foldout cushion exposing a work surface.

Abstract: Processes for die casting metals are provided, which are more energy efficient and less expensive than the current metal die casting processes. The die casting processes discussed herein utilize a water-soluble die release fluid and hydraulic equipment which uses water-insoluble hydraulic fluid. By doing so, the hydraulic fluid and die release fluid present in the waste collected from the die casting process can be collected via separation techniques. One or both of the collected hydraulic fluid and die release fluid may then be re-used in the same die casting process, another die casting process, or other processes altogether.

Abstract: The present invention provides processes for quenching metals which are more energy efficient and less expensive than the current metal quenching processes. The quenching processes utilize a water-soluble aqueous quenching fluid and hydraulic equipment which uses water-insoluble, fire-resistant hydraulic fluid for an immersion or spray application. During quenching of metal in a quenching immersion bath or by quenching spray process, the aqueous quenching fluid becomes contaminated with the hydraulic fluid and no longer meets its quenching specifications. The process and system described herein involves removing and heating the contaminated quenching fluid to enable separation of the quenching fluid from the contaminants and recycling of the used quenching fluid back into a functional quenching bath or functional quenching spray. The separated hydraulic fluid is then recycled as fuel, e.g., biofuel or waste fuel, thereby reducing the amounts of waste product associated with quenching metals.

Abstract: The present invention provides processes for die casting metals which are more energy efficient and less expensive than the current metal die casting processes. The die casting processes discussed herein utilize a water-soluble die release fluid and hydraulic equipment which uses water-insoluble hydraulic fluid. By doing so, the hydraulic fluid and die release fluid present in the waste collected from the die casting process can be collected via separation techniques. One or both of the collected hydraulic fluid and die release fluid may then be re-used in the same die casting process, another die casting process, or another processes altogether.

Abstract: Systems, methodologies, media, computing devices, network adapters, and other embodiments associated with network communications are described. One exemplary system embodiment includes a multi-drop Ethernet network.

Abstract: A method for use in a computer system includes a first revision compatibility descriptor identifying a first plurality of compatible combinations of field-programmable unit codes. The method includes steps of: (A) determining whether the first revision compatibility descriptor identifies first field-programmable unit code for use in a first field-programmable unit as being compatible with the computer system; and (B) if the first revision compatibility descriptor does not identify the first field-programmable unit code as being compatible with the computer system, performing a step of updating the first revision compatibility descriptor to identify the first field-programmable unit code as being compatible with the computer system.

Abstract: One embodiment of a non-volatile memory system comprises block-accessible non-volatile memory, random access memory arranged to be linearly addressable by a processor as part of the processor's memory address space, to be read from and written to by the processor, and logic interposed between the block-accessible non-volatile memory and the random access memory and arranged to write parts of the content of the random access memory in blocks to blocks of the non-volatile, block-accessible memory. The logic is arranged to monitor processor writes to the random access memory, and to write blocks of the random access memory that differ from a most recent copy in the non-volatile, block-accessible memory to the non-volatile, block-accessible memory.