Patents by Inventor Edward A. Esposito

Edward A. Esposito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10386315
    Abstract: A method of determining thermal properties of a sample using differential scanning calorimetry (DSC), the method comprises injecting a first separation fluid, a sample plug, and a second separation fluid into a sample cell. The first separation fluid and the sample plug have a first separation interface, and the sample plug and the second fluid have a second separation interface. The method further comprises injecting a reference fluid into a reference cell, heating the sample cell and reference cell, and determining thermal properties of the sample using DSC analysis.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: August 20, 2019
    Assignee: Malvern Panalytical Inc.
    Inventors: Vishal Patil, Ronan O'Brian, Edward A. Esposito, Ben E. Pattison
  • Publication number: 20170299532
    Abstract: A method of determining thermal properties of a sample using differential scanning calorimetry (DSC), the method comprises injecting a first separation fluid, a sample plug, and a second separation fluid into a sample cell. The first separation fluid and the sample plug have a first separation interface, and the sample plug and the second fluid have a second separation interface. The method further comprises injecting a reference fluid into a reference cell, heating the sample cell and reference cell, and determining thermal properties of the sample using DSC analysis.
    Type: Application
    Filed: April 19, 2016
    Publication date: October 19, 2017
    Applicant: Malvern Instruments Incorporated
    Inventors: Vishal Patil, Ronan O'Brien, Edward A. Esposito, Ben E. Pattison
  • Patent number: 8578493
    Abstract: A method and system to detect botnet beaconing event based on a beacon detection rule set to generate a beacon alert, which is in turn used to trigger an elevated exfiltration detection activity by reducing various thresholds in an exfiltration detection rule set.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: November 5, 2013
    Assignee: Narus, Inc.
    Inventors: Joe Cowan, Robert Edward Esposito, Travis Edward Dawson, Supranamaya Ranjan
  • Patent number: 8541190
    Abstract: Methods and materials use template-directed assembly of polypeptides and optionally additional reagents to analyze the functionality of membrane-associated proteins, such as, for example, portions of transmembrane proteins, membrane-associated proteins, and others proteins that bind to transmembrane proteins and membrane-associated proteins, and to analyze the effect of test compounds or mutations on the functionality of same. The methods and materials of the present application provide a more native-like environment for analyzing the functionality of membrane-associated proteins, and thus provide effective tools for studies involving the detection of the level of enzyme activity of such proteins in an environment that closely resembles the native environment in the cell, and for novel manufacturing processes.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: September 24, 2013
    Inventors: Robert M. Weis, Anthony L. Shrout, Edward A. Esposito
  • Publication number: 20080003631
    Abstract: Methods and materials use template-directed assembly of polypeptides and optionally additional reagents to analyze the functionality of membrane-associated proteins, such as, for example, portions of transmembrane proteins, membrane-associated proteins, and others proteins that bind to transmembrane proteins and membrane-associated proteins, and to analyze the effect of test compounds or mutations on the functionality of same. The methods and materials of the present application provide a more native-like environment for analyzing the functionality of membrane-associated proteins, and thus provide effective tools for studies involving the detection of the level of enzyme activity of such proteins in an environment that closely resembles the native environment in the cell, and for novel manufacturing processes.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 3, 2008
    Inventors: Robert Weis, Anthony Shrout, Edward Esposito