Patents by Inventor Edward A. Kohler

Edward A. Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210031002
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Application
    Filed: October 19, 2020
    Publication date: February 4, 2021
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 10806891
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 20, 2020
    Assignee: Cook Regentec LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 10326365
    Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: June 18, 2019
    Assignee: Intersil Americas LLC
    Inventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
  • Publication number: 20190060611
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Application
    Filed: October 30, 2018
    Publication date: February 28, 2019
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 10155099
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: December 18, 2018
    Assignee: Cook Regentec LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 10058675
    Abstract: A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: August 28, 2018
    Assignee: Cook Regentec LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Publication number: 20180145591
    Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.
    Type: Application
    Filed: November 2, 2017
    Publication date: May 24, 2018
    Applicant: Intersil Americas LLC
    Inventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
  • Patent number: 9812962
    Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: November 7, 2017
    Assignee: INTERSIL AMERICAS LLC
    Inventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
  • Publication number: 20170093283
    Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.
    Type: Application
    Filed: April 5, 2016
    Publication date: March 30, 2017
    Inventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
  • Publication number: 20140207107
    Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.
    Type: Application
    Filed: March 6, 2014
    Publication date: July 24, 2014
    Applicant: Translational Biologic Infusion Catheter, LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Publication number: 20140114239
    Abstract: A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: Translational Biologic Infusion Catheter, LLC
    Inventors: Nabil Dib, Robert Edward Kohler
  • Patent number: 8207786
    Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.
    Type: Grant
    Filed: April 25, 2011
    Date of Patent: June 26, 2012
    Assignee: Kenet, Inc.
    Inventors: Edward Kohler, Michael P. Anthony
  • Publication number: 20110199151
    Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.
    Type: Application
    Filed: April 25, 2011
    Publication date: August 18, 2011
    Applicant: Kenet, Inc.
    Inventors: EDWARD KOHLER, Michael P. Anthony
  • Patent number: 7932767
    Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: April 26, 2011
    Assignee: Kenet, Inc.
    Inventors: Edward Kohler, Michael P. Anthony
  • Publication number: 20090146717
    Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.
    Type: Application
    Filed: December 8, 2008
    Publication date: June 11, 2009
    Applicant: Kenet, Inc.
    Inventors: Edward Kohler, Michael P. Anthony
  • Patent number: 7326219
    Abstract: The present invention relates to a transmyocardial implant placement device with an introducer, a transmyocardial implant mounted about the introducer, a wound closure clip engaged to the introducer adjacent the transmyocardial implant. The introducer is adapted to be inserted through a lumen of a coronary vessel and a myocardium of a patient into a chamber of the patient's heart and form a blood flow pathway through the myocardium between the heart chamber and the coronary vessel. When the introducer is inserted, the wound closure clip engages an outer wall of the coronary vessel and the transmyocardial implant extends from the heart chamber to the lumen of the coronary vessel. The transmyocardial implant is expanded in the blood flow pathway and the introducer retracted, leaving the transmyocardial implant in the within the blood flow pathway.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: February 5, 2008
    Assignee: Wilk Patent Development
    Inventors: David H. Mowry, Robert Edward Kohler
  • Patent number: 7274052
    Abstract: A charge splitter for separating an incoming charge packet into two outgoing packets while the charge is in a static state, i.e., not while it is flowing down a channel or over a barrier. A splitting gate may have a biasing charge impressed upon it, such as via the application of voltage or current sources to opposite ends thereof, applying a bias to a semiconductor body portion of the gate structure, or by physically separate the splitting gate into multiple sections that each have different applied voltages or currents When discharge barrier gates are operated, different amounts of charge will thus flow to different output storage gates.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: September 25, 2007
    Assignee: Kenet, Inc.
    Inventors: Michael P. Anthony, Edward Kohler
  • Publication number: 20070161148
    Abstract: A technique for forming Charge-Coupled Devices (CCDS) in a conventional Complementary Metal Oxide Semiconductor (CMOS) process. A number of single-layer polysilicon gates are formed on an as-grown, native doped silicon substrate, with gaps between them. Masking is used to selectively dope the gates while preventing doping of the silicon in the gaps. Masking may likewise be used to selectively silicide the gates while preventing silicide formation in the gaps. Conventional source-drain processing produces input/output diffusions for the CCD.
    Type: Application
    Filed: February 20, 2007
    Publication date: July 12, 2007
    Inventors: Gerhard Sollner, Lawrence Kushner, Michael Anthony, Edward Kohler, Wesley Grant
  • Patent number: 7179676
    Abstract: A technique for forming Charge-Coupled Devices (CCDs) in a conventional Complementary Metal Oxide Semiconductor (CMOS) process. A number of single-layer polysilicon gates are formed on an as-grown, native doped silicon substrate, with gaps between them. Masking is used to selectively dope the gates while preventing doping of the silicon in the gaps. Masking may likewise be used to selectively silicide the gates while preventing silicide formation in the gaps. Conventional source-drain processing produces input/output diffusions for the CCD.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: February 20, 2007
    Assignee: Kenet, Inc.
    Inventors: Gerhard Sollner, Lawrence J. Kushner, Michael P. Anthony, Edward Kohler, Wesley Grant
  • Publication number: 20070007555
    Abstract: A charge splitter for separating an incoming charge packet into two outgoing packets while the charge is in a static state, i.e., not while it is flowing down a channel or over a barrier. A splitting gate may have a biasing charge impressed upon it, such as via the application of voltage or current sources to opposite ends thereof, applying a bias to a semiconductor body portion of the gate structure, or by physically separate the splitting gate into multiple sections that each have different applied voltages or currents When discharge barrier gates are operated, different amounts of charge will thus flow to different output storage gates.
    Type: Application
    Filed: July 6, 2005
    Publication date: January 11, 2007
    Applicant: Kenet, Inc.
    Inventors: Michael Anthony, Edward Kohler