Patents by Inventor Edward A. Kohler
Edward A. Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210031002Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: ApplicationFiled: October 19, 2020Publication date: February 4, 2021Inventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10806891Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: GrantFiled: October 30, 2018Date of Patent: October 20, 2020Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10326365Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.Type: GrantFiled: November 2, 2017Date of Patent: June 18, 2019Assignee: Intersil Americas LLCInventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
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Publication number: 20190060611Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: ApplicationFiled: October 30, 2018Publication date: February 28, 2019Inventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10155099Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: GrantFiled: March 6, 2014Date of Patent: December 18, 2018Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Patent number: 10058675Abstract: A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member.Type: GrantFiled: December 31, 2013Date of Patent: August 28, 2018Assignee: Cook Regentec LLCInventors: Nabil Dib, Robert Edward Kohler
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Publication number: 20180145591Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.Type: ApplicationFiled: November 2, 2017Publication date: May 24, 2018Applicant: Intersil Americas LLCInventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
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Patent number: 9812962Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.Type: GrantFiled: April 5, 2016Date of Patent: November 7, 2017Assignee: INTERSIL AMERICAS LLCInventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
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Publication number: 20170093283Abstract: One embodiment pertains to a method including transitioning a logic state of at least one enable signal. A first power transistor begins to turn off. A parameter level of the input of the first power transistor is directly sensed. A second power transistor is turned off when the parameter level is less than a threshold level.Type: ApplicationFiled: April 5, 2016Publication date: March 30, 2017Inventors: Alexandro Leoncini, Edward Kohler, Timmy Lok
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Publication number: 20140207107Abstract: A method for infusing a liquid into a patient's vasculature in accordance with an infusion protocol is disclosed. For this method, an infusion catheter having a multi-lumen infusion unit that is mounted adjacent the catheter's distal end is positioned in an artery within a predetermined distance from an intended target tissue surface. An inflation balloon is then deployed to at least partially occlude the artery and a force is exerted on the liquid to establish a flow rate for the liquid in the catheter. Specifically, the force is exerted to infuse the liquid from the catheter through the infusion unit and into the vasculature with a homogeneous distribution of the liquid to cover the intended surface of the target tissue. The flow rate can be established in accordance with an infusion protocol that is characterized by time and liquid volume parameters based on viscosity and pressure values in the liquid.Type: ApplicationFiled: March 6, 2014Publication date: July 24, 2014Applicant: Translational Biologic Infusion Catheter, LLCInventors: Nabil Dib, Robert Edward Kohler
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Publication number: 20140114239Abstract: A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member.Type: ApplicationFiled: December 31, 2013Publication date: April 24, 2014Applicant: Translational Biologic Infusion Catheter, LLCInventors: Nabil Dib, Robert Edward Kohler
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Patent number: 8207786Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.Type: GrantFiled: April 25, 2011Date of Patent: June 26, 2012Assignee: Kenet, Inc.Inventors: Edward Kohler, Michael P. Anthony
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Publication number: 20110199151Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.Type: ApplicationFiled: April 25, 2011Publication date: August 18, 2011Applicant: Kenet, Inc.Inventors: EDWARD KOHLER, Michael P. Anthony
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Patent number: 7932767Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.Type: GrantFiled: December 8, 2008Date of Patent: April 26, 2011Assignee: Kenet, Inc.Inventors: Edward Kohler, Michael P. Anthony
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Publication number: 20090146717Abstract: A technique for increasing the charge storage capacity of a charge storage device without changing its inherent charge transfer function. The technique may be used to implement a charge domain signal processing circuits such as Analog to Digital Converters (ADCs) used in digital radio frequency signal receivers.Type: ApplicationFiled: December 8, 2008Publication date: June 11, 2009Applicant: Kenet, Inc.Inventors: Edward Kohler, Michael P. Anthony
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Patent number: 7326219Abstract: The present invention relates to a transmyocardial implant placement device with an introducer, a transmyocardial implant mounted about the introducer, a wound closure clip engaged to the introducer adjacent the transmyocardial implant. The introducer is adapted to be inserted through a lumen of a coronary vessel and a myocardium of a patient into a chamber of the patient's heart and form a blood flow pathway through the myocardium between the heart chamber and the coronary vessel. When the introducer is inserted, the wound closure clip engages an outer wall of the coronary vessel and the transmyocardial implant extends from the heart chamber to the lumen of the coronary vessel. The transmyocardial implant is expanded in the blood flow pathway and the introducer retracted, leaving the transmyocardial implant in the within the blood flow pathway.Type: GrantFiled: September 9, 2002Date of Patent: February 5, 2008Assignee: Wilk Patent DevelopmentInventors: David H. Mowry, Robert Edward Kohler
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Patent number: 7274052Abstract: A charge splitter for separating an incoming charge packet into two outgoing packets while the charge is in a static state, i.e., not while it is flowing down a channel or over a barrier. A splitting gate may have a biasing charge impressed upon it, such as via the application of voltage or current sources to opposite ends thereof, applying a bias to a semiconductor body portion of the gate structure, or by physically separate the splitting gate into multiple sections that each have different applied voltages or currents When discharge barrier gates are operated, different amounts of charge will thus flow to different output storage gates.Type: GrantFiled: July 6, 2005Date of Patent: September 25, 2007Assignee: Kenet, Inc.Inventors: Michael P. Anthony, Edward Kohler
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Publication number: 20070161148Abstract: A technique for forming Charge-Coupled Devices (CCDS) in a conventional Complementary Metal Oxide Semiconductor (CMOS) process. A number of single-layer polysilicon gates are formed on an as-grown, native doped silicon substrate, with gaps between them. Masking is used to selectively dope the gates while preventing doping of the silicon in the gaps. Masking may likewise be used to selectively silicide the gates while preventing silicide formation in the gaps. Conventional source-drain processing produces input/output diffusions for the CCD.Type: ApplicationFiled: February 20, 2007Publication date: July 12, 2007Inventors: Gerhard Sollner, Lawrence Kushner, Michael Anthony, Edward Kohler, Wesley Grant
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Patent number: 7179676Abstract: A technique for forming Charge-Coupled Devices (CCDs) in a conventional Complementary Metal Oxide Semiconductor (CMOS) process. A number of single-layer polysilicon gates are formed on an as-grown, native doped silicon substrate, with gaps between them. Masking is used to selectively dope the gates while preventing doping of the silicon in the gaps. Masking may likewise be used to selectively silicide the gates while preventing silicide formation in the gaps. Conventional source-drain processing produces input/output diffusions for the CCD.Type: GrantFiled: March 28, 2005Date of Patent: February 20, 2007Assignee: Kenet, Inc.Inventors: Gerhard Sollner, Lawrence J. Kushner, Michael P. Anthony, Edward Kohler, Wesley Grant
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Publication number: 20070007555Abstract: A charge splitter for separating an incoming charge packet into two outgoing packets while the charge is in a static state, i.e., not while it is flowing down a channel or over a barrier. A splitting gate may have a biasing charge impressed upon it, such as via the application of voltage or current sources to opposite ends thereof, applying a bias to a semiconductor body portion of the gate structure, or by physically separate the splitting gate into multiple sections that each have different applied voltages or currents When discharge barrier gates are operated, different amounts of charge will thus flow to different output storage gates.Type: ApplicationFiled: July 6, 2005Publication date: January 11, 2007Applicant: Kenet, Inc.Inventors: Michael Anthony, Edward Kohler