Patents by Inventor Edward A. Lally

Edward A. Lally has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PHENYL-PYRAZOLES USEFUL AS MODULATERS OF THE 5-HT2A SEROTONIN RECEPTOR
    Publication number: 20180186748
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Application
    Filed: September 11, 2017
    Publication date: July 5, 2018
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin M. Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally
  • Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HTserotonin receptor
    Patent number: 9783502
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: October 10, 2017
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally
  • CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PHENYL-PYRAZOLES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR
    Publication number: 20160272591
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Application
    Filed: October 23, 2015
    Publication date: September 22, 2016
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally
  • Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HTserotonin receptor
    Patent number: 9199940
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: December 1, 2015
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin M. Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally
  • Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-HTserotonin receptor useful for the treatment of disorders related thereto
    Patent number: 8980891
    Abstract: Provided are certain solvates of 3-methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions comprising such solvates and methods for their use.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 17, 2015
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Scott Stirn, Edward A. Lally
  • CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PHENYL-PYRAZOLES USEFUL AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR
    Publication number: 20130296321
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 7, 2013
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin M. Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally, Jonathan Duffield
  • Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HTserotonin receptor
    Patent number: 8481535
    Abstract: The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: July 9, 2013
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Ashwin M. Krishnan, Nainesh Shah, Ryan M. Hart, Mark Macias, Edward A. Lally, Jonathan Duffield
  • CRYSTALLINE FORMS OF CERTAIN 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20120252813
    Abstract: Provided are certain solvates of 3-methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions comprising such solvates and methods for their use.
    Type: Application
    Filed: December 16, 2010
    Publication date: October 4, 2012
    Inventors: Scott Stirn, Edward A. Lally
  • Processes for preparing substituted N-aryl-N?-[3-(1H-pyrazol-5-YL) phenyl] ureas and intermediates thereof
    Patent number: 7812176
    Abstract: The present invention is directed to processes for the preparation of substituted phenylpyrazole ureas of Formula (I), that are useful as 5-HT2A serotonin receptor modulators for the treatment of disease.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: October 12, 2010
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: John Robert Fritch, Fiona M. Carleton, Edward A. Lally, Hongmei Li, Bradley Teegarden
  • Processes for preparing pyrazolo[3,4-d]pyrimidine ethers
    Patent number: 7425630
    Abstract: The present invention relates to processes for preparing pyrazolo[3,4-d]pyrimidine ether compounds that are modulators of glucose metabolism and therefore useful in the treatment of metabolic disorders such as diabetes and obesity.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: September 16, 2008
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Edward A. Lally, Naomi S. Kato, Marlon Carlos, Natalie Rodriguez
  • Process for Preparing Substituted Phenylpyrazole Ureas
    Publication number: 20080194836
    Abstract: The present invention is directed to processes for the preparation of substituted phenylpyrazole ureas of Formula (I) that are useful as 5-HT2A serotonin receptor modulators for the treatment of disease.
    Type: Application
    Filed: January 25, 2006
    Publication date: August 14, 2008
    Inventors: Tawfik Gharbaoui, Claudia Averbuj, Marlony Carlos, Edward A. Lally, Dipanjan Sengupta, John Robert Fritch
  • Processes for Preparing Substituted N-Aryl-N'-[3-(1H-Pyrazol-5-Yl) Phenyl] Ureas and Intermediates Thereof
    Publication number: 20070293685
    Abstract: The present invention is directed to processes for the preparation of substituted phenylpyrazole ureas of Formula (I), that are useful as 5-HT2A serotonin receptor modulators for the treatment of disease.
    Type: Application
    Filed: July 21, 2004
    Publication date: December 20, 2007
    Applicant: Arena Pharmaceuticals, Inc.
    Inventors: John Fritch, Fiona Carleton, Edward Lally, Hongmei Li, Bradley Teegarden
  • Processes for preparing pyrazolo[3,4-d]pyrimidine ethers
    Publication number: 20060154940
    Abstract: The present invention relates to processes for preparing pyrazolo[3,4-d]pyrimidine ether compounds that are modulators of glucose metabolism and therefore useful in the treatment of metabolic disorders such as diabetes and obesity.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 13, 2006
    Inventors: Tawfik Gharbaoui, Dipanjan Sengupta, Edward Lally, Naomi Kato, Marlon Carlos, Natalie Rodriguez