Abstract: Multiple observations using a reconfigurable space-based telescope are performed by independently targeting one or more sensor units, within a field of view, relative to a main body of the space-based telescope. The sensor units are capable of simultaneously obtaining an image of one or more targets, respectively. At least one of the sensor units is independently retargetable relative to the main body of the space-based telescope to obtain an image of at least one other target. Further, the sensor units are independently maneuverable in formation relative to the main body of the space-based telescope to obtain various lines of sight without changing an optical axis of the main body of the space-based telescope.