Abstract: The present disclosure relates to recombinant RNA molecules encoding an oncolytic virus genome. The present disclosure further relates to the encapsulation of the recombinant RNA molecules and the use of the recombinant RNA molecules and/or particles for the treatment and prevention of cancer.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. Furthermore, the portion of the data structure that is forwarded to the receiving forum participant includes data in the data structure that corresponds to each of the selected one or more forms.

Abstract: A system is provided for social interactive content development of a plurality of art assets for an interactive video game. The system includes a proximity analyzer for determining proximity relationships amongst the plurality of art assets, each of the art assets being defined for display during execution of the interactive video game. An activity monitor is provided for monitoring access to the plurality of art assets. And a social inference engine is provided for initiating a communication in response to triggering a predefined access threshold set for a specific art asset based on a proximity relationship of the specific art asset to a proximate art asset.

Abstract: A system is provided for social interactive content development of a plurality of art assets for an interactive video game. The system includes a proximity analyzer for determining proximity relationships amongst the plurality of art assets, each of the art assets being defined for display during execution of the interactive video game. An activity monitor is provided for monitoring access to the plurality of art assets. And a social inference engine is provided for initiating a communication in response to triggering a predefined access threshold set for a specific art asset based on a proximity relationship of the specific art asset to a proximate art asset.

Abstract: A system for social interactive code development of a plurality of code modules is provided. The system includes an activity monitor for monitoring access to one or more of the plurality of code modules. The system further includes a social feedback engine for initiating a communication based on triggering a predefined access threshold set for at least part of a specific one of the plurality of code modules.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. Furthermore, the portion of the data structure that is forwarded to the receiving forum participant includes data in the data structure that corresponds to each of the selected one or more forms.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. Furthermore, the portion of the data structure that is forwarded to the receiving forum participant includes data in the data structure that corresponds to each of the selected one or more forms.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. Furthermore, the portion of the data structure that is forwarded to the receiving forum participant includes data in the data structure that corresponds to each of the selected one or more forms.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. A representative function includes a determination whether the receiving participant is a paid subscriber.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. A representative function includes a determination whether the receiving participant is a paid subscriber.

Abstract: A method of communicating digitized speech from a transmitting forum participant comprises the step of receiving a data structure that includes said digitized speech. The data structure is analyzed to determine whether the digitized speech is redundantly represented in a plurality of forms in the data structure. A portion of the data structure is forwarded to a receiving forum participant, thereby communicating the digitized speech from the transmitting forum participant. In this method, when the digitized speech is redundantly represented in the data structure in a plurality of forms, the forwarding step includes a step of selecting one or more forms, based on a function, from the plurality of forms in the data structure. A representative function includes a determination whether the receiving participant is a paid subscriber.

Abstract: A method of visually identifying speaking participants in a multi-participant event such as an audio conference or an on-line game includes the step of receiving packets of digitized sound from a network connection. The identity of the participant associated with each packet is used to route the packet to a channel buffer or an overflow buffer. Each channel buffer may be assigned to a single participant in the multi-participant. A visual identifier module updates the visual identifier associated with participants that have been assigned a channel buffer. In some embodiments, the appearance of the visual identifier associated with the participant is dependent upon the differential of an acoustic parameter derived from content in the associated buffer channel and a reference value stored in a participant record.

Abstract: A system for communicating digitally-encoded acoustic information across a computer network between computers. The system includes a plurality of client computers coupled together via a computer network. Each client computer includes a communications interface, memory, a sound processor and a sound mixer. The communications interface is coupled to the computer network and receives digitally-encoded acoustic signals from the other client computers attached to the computer network. The memory is coupled to the communications interface and stores separately the received acoustic signals. The sound processor is coupled to the memory and enhances separately the stored acoustic signals. The sound mixer is coupled to the sound processor and mixes the enhanced acoustic signals to produce a mixed acoustic signal.

Abstract: A coffee brewer with means for dispensing controlled quantities of hot water comprising well known coffee brewing means including a main water tank having a heater therein, means for introducing water to the tank and a discharge conduit for passing coffee brewing water from the tank wherein there is provided a separate and preferably removable, closed water bottle mounted for gravity feed of water to the tank, a discharge conduit connecting the bottle to the tank, the normal operational position of the end of which proximal to the tank being located such that water normally covers it before water in the tank reaches a level sufficient to pass through the conduit for discharging brewing water, a separate, valve controlled single-cup water discharge spigot connected to the tank beneath the level in the tank of the end of the conduit connecting the bottle with the tank, a valve normally blocking the gravitational discharge of water from the bottle and valve actuating means which open the valve when the bottle is

Abstract: A coffee brewer with means for dispensing controlled quantities of hot water comprising a water tank, means for heating the water in the tank, water inlet means connected to the tank, a water discharge siphon connected at one end to the tank, the opposite end of the siphon being at a level beneath the first said end thereof, a water reservoir, a supply conduit connecting the reservoir to the water tank, the end of the supply conduit in the tank being positioned beneath the level of the end of the siphon in the tank, the said reservoir being closed except for said supply conduit and being positioned for gravity discharge into said water tank, a water discharge conduit connected at one end to the tank beneath the level of the end of said supply conduit therein, and valve means in the said discharge conduit.

Abstract: A metering valve, preferably electromagnetically actuatable, for the successive delivery of precisely measured volumes of fluid irrespective of inlet fluid pressure, including a valve core, slidably mounted in a cavity in the valve body, the top of the core closing a normally open fluid inlet when the core is moved to an uppermost position, and the bottom of the core closing a fluid discharge outlet when in its normal lowermost position, the volume of fluid discharged being the volumetric difference between the volume of the cavity and the volumetric displacement of the core.