Abstract: The debt issuance of a company are credit enhanced via an investment platform wherein the company's issuances and investments are both subject to a master netting agreement between common counterparties, thereby creating a fully hedged transaction with an investible present value monetization of the future income stream for purposes of reinvesting. The Investment Platform comprises a proprietary Cross Settlement, Credit Enhancement, Risk-Mitigation and Netting System that has a hedged investment structure that automatically qualifies for credit enhancement wherein non-investment grade debt issuances can be transformed into investment grade debt issuances. The Investment Platform is powered by a proprietary investment algorithm and make-whole algorithm that matches movements in a selected benchmark rate or indices.

Abstract: An investment process transacted by means of an Investment Exchange that is powered by a proprietary reallocation algorithm that reallocates the cash flows on an issuer's private placement Investment Unit offering and works by internally re-generating, redistributing and rebalancing the various securities comprising the Investment Unit with a means of monetizing the income stream wherein the cash flows of the securities comprising the Investment Unit are reallocated, repackaged, matched and hedged in a cash-settled capital raising process to provide superior returns to primary and secondary investors and a relatively low amount of stock dilution and no stock price discount to existing shareholders of an issuer of equity securities.

Abstract: The debt issuance of a company are credit enhanced via an investment platform wherein the company's issuances and investments are both subject to a master netting agreement between common counterparties, thereby creating a fully hedged transaction with an investible present value monetization of the future income stream for purposes of reinvesting. The Investment Platform comprises a proprietary Cross Settlement, Credit Enhancement, Risk-Mitigation and Netting System that has a hedged investment structure that automatically qualifies for credit enhancement wherein non-investment grade debt issuances can be transformed into investment grade debt issuances. The Investment Platform is powered by a proprietary investment algorithm and make-whole algorithm that matches movements in a selected benchmark rate or indices.

Abstract: Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transfection under serum-free conditions. In preferred embodiments, the cells of use are SpESF or SpESF-X cells.

Abstract: Disclosed are compositions and methods for increasing the longevity of a cell culture and permitting the increased production of proteins, preferably recombinant proteins, such as antibodies, peptides, enzymes, growth factors, interleukins, interferons, hormones, and vaccines. Cells transfected with an apoptosis-inhibiting gene or vector, such as a triple mutant Bcl-2 gene, can survive longer in culture, resulting in extension of the state and yield of protein biosynthesis. Such transfected cells exhibit maximal cell densities that equal or exceed the maximal density achieved by the parent cell lines. Transfected cells can also be pre-adapted for growth in serum-free medium, greatly decreasing the time required to obtain protein production in serum-free medium. In certain methods, the pre-adapted cells can be used for protein production following transfection under serum-free conditions. In preferred embodiments, the cells of use are SpESF or SpESF-X cells.

Abstract: A method and apparatus for controlling universal exhaust gas oxygen (UEGO) sensors comprises an application specific integrated circuit (ASIC) that includes a sensor control utilizing proportional-integral-derivative control loop, sensor drivers for generating pumping currents that reflect the changes of voltages representative of oxygen levels in the reference and test chambers of the UEGO sensor, a communication circuit for communicating with an engine control module, and output buffers for conditioning replications of the pumping current for delivery to an output circuit. In addition to the ASIC, a sensor interface conditions the sensor signals and an output circuit transforms the pumping circuit replications to compatible inputs for the engine control module. Preferably, all of the circuits are formed on a portion of a circuit board in the engine control module. A trim compensation circuit compensates for sensor deviation from an ideal performance standard.