Patents by Inventor Edward A. Sasse

Edward A. Sasse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Competitive enzyme-linked immunoassay
    Patent number: 4235960
    Abstract: A competitive enzyme-linked immunoassay for a soluble analyte in which the analyte in the unknown sample and the same analyte attached to a solid phase (immunosorbent) compete for a selected quantity of a soluble first antibody to the substance; a second or bridging antibody is then linked to any first antibody linked to the immunosorbent as a result of the competitive reaction, following which a soluble enzyme/antibody immune complex is linked to bridging antibody on the immunosorbent. The enzymatic activity associated with the thusly-formed enzyme-immunosorbent complex or with the non-immunosorbent fraction of enzyme is measured to determine the presence and/or concentration of analyte in the unknown sample.
    Type: Grant
    Filed: July 29, 1977
    Date of Patent: November 25, 1980
    Assignee: The Medical College of Wisconsin, Inc.
    Inventors: Edward A. Sasse, Donald E. Yorde