Patents by Inventor Edward A. Steele
Edward A. Steele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11658888Abstract: A network timing view provides enhanced visualization for synch timing in support of mobile (4G/5G deployments) and others requiring sync. It allows network managers to view relevant synch data both textually and graphically displayed on the network map nodes and links in a unified view. The user is able to select the appropriate filter on the network map to show the 1588/SyncE connectivity and relevant nodes that are participating in delivering timing. It allows a user to trace the timing path from any timing device upstream to the clock source. It also allows the user to interactively discover and navigate downstream timing paths from any timing device, similar to exploring a tree hierarchy. The timing topology and path data provided allows a user to investigate the timing network for troubleshooting purposes such as timing alarms and events, sync problems, clock quality levels and clock states.Type: GrantFiled: February 25, 2022Date of Patent: May 23, 2023Assignee: Ciena CorporationInventors: Peter Brett Sinclair, David Charles Steele, Blair Edward Paul Moxon
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Publication number: 20230047158Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: ApplicationFiled: August 9, 2022Publication date: February 16, 2023Inventors: Christoph SCHUMACHER, Walter FUHRER, Ronald Edward STEELE
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Patent number: 11447491Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: GrantFiled: August 12, 2020Date of Patent: September 20, 2022Assignee: DAMIAN PHARMA AGInventors: Christoph Schumacher, Walter Fuhrer, Ronald Edward Steele
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Publication number: 20210169861Abstract: The present invention relates to a composition for use in the treatment of a disease or disorder, wherein said disease or disorder is preferably a disease or disorder in which aldosterone overexposure contributes to the symptoms of said disease or disorder, said composition comprises a compound which is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine or a pharmaceutically acceptable salt thereof, wherein preferably said compound is (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazolium[1,5-a]pyridine dihydrogen phosphate, and wherein said compound has an enantiomeric excess (ee) of the (R) form higher than or equal to 97%, and wherein said composition is administered once daily to a subject in need thereof.Type: ApplicationFiled: May 2, 2019Publication date: June 10, 2021Inventors: Ronald Edward STEELE, Christoph SCHUMACHER
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Publication number: 20210024519Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: ApplicationFiled: August 12, 2020Publication date: January 28, 2021Inventors: Christoph SCHUMACHER, Walter FUHRER, Ronald Edward STEELE
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Patent number: 10822332Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: GrantFiled: October 26, 2017Date of Patent: November 3, 2020Assignee: DAMIAN PHARMA AGInventors: Christoph Schumacher, Walter Fuhrer, Ronald Edward Steele
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Patent number: 10745769Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with a treatment formulation and a solid particulate material in a sealed apparatus wherein the treatment formulation comprises a tanning agent or a tannery process agent. The method can comprise applying the tanning agent or tannery process agent to the animal substrate wherein at least some of the agent so applied originates from the treatment formulation. There is also disclosed an animal substrate obtained by the method. The treatment formulation can be aqueous.Type: GrantFiled: April 11, 2014Date of Patent: August 18, 2020Assignee: Xeros LimitedInventor: John Edward Steele
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Patent number: 10494590Abstract: The invention provides a cleaning formulation comprising a multiplicity of solid cleaning particles, wherein the solid cleaning particles comprise polymeric particles and at least one cleaning agent, wherein the at least one cleaning agent is immobilised on the surface of the polymeric particles. Typically the at least one cleaning agent is immobilised on the surface of the polymeric particles by means of chemical bonds, typically ionic bonds, hydrogen bonds, covalent bonds, polar bonds, or bonds formed by virtue of unequal charge distributions between polymeric particles and immobilised materials. The invention also provides a method for the cleaning of a substrate, the method comprising the treatment of the substrate with a formulation according to the invention, and a method for the preparation of the cleaning formulation of the invention which comprises treating a multiplicity of polymeric particles with at least one cleaning agent.Type: GrantFiled: July 8, 2013Date of Patent: December 3, 2019Assignee: Xeros LimitedInventors: Elizabeth Jean Abercrombie, Ana America Tellechea Lopez, John Edward Steele, Stephen Derek Jenkins
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Publication number: 20190292180Abstract: The present invention relates to a compound selected from (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine and a pharmaceutically acceptable salt thereof, and in particular to the phosphate salt of (R)-(+)-5-(p-cyanophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine, both having preferably an enantiomeric excess of the (R) form higher than or equal to 97%. Furthermore, the present invention relates to pharmaceutical compositions comprising the same, their use as a medicament and in methods of treatment of diseases and disorders in humans including women of child bearing potential and pediatric patients in which aldosterone over-exposure contributes to the deleterious effects of said diseases or disorders, as well as processes for preparing said inventive compounds.Type: ApplicationFiled: October 26, 2017Publication date: September 26, 2019Applicant: DAMIAN PHARMA AGInventors: Christoph SCHUMACHER, Walter FUHRER, Ronald Edward STEELE
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Patent number: 10301691Abstract: A method for tanning an animal substrate comprising the steps: i) agitating the animal substrate with a chromium-free tanning agent; and ii) agitating the animal substrate with a tanning agent having an oxazolidine group; wherein at least some of the agitation is performed in the presence of a solid particulate material having an average particle size of from 1 to 500 mm.Type: GrantFiled: October 1, 2015Date of Patent: May 28, 2019Assignee: Xeros LimitedInventors: Addis Duki Feyisa, John Edward Steele
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Publication number: 20180134994Abstract: Apparatus (200) for the treatment of one or more substrates comprising a treatment chamber configured to receive a liquid medium and one or more substrates; a supply of a treatment gas comprising ozone; and one or more conduits to convey said treatment gas to a bubble generator (41) wherein said bubble generator is operable to form bubbles of said treatment gas in said liquid medium, wherein the apparatus comprises a multiplicity of solid particles (46). A method of treating one or more substrates, the method comprising agitating said one or more substrates in a treatment formulation comprising a multiplicity of solid particles, a liquid medium and bubbles of ozone.Type: ApplicationFiled: June 17, 2016Publication date: May 17, 2018Applicants: Xeros Limited, Xeros LimitedInventors: John Edward STEELE, William Bauer Jay ZIMMERMAN
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Publication number: 20180058186Abstract: A method in one embodiment includes obtaining produced water from at least one of drilling, completion, or hydrocarbon production. The method also includes separating the produced water into desalinated water and produced salt. Further, the method includes coating the produced salt with resin to provide coated produced salt.Type: ApplicationFiled: August 31, 2016Publication date: March 1, 2018Inventors: Mahendra L. Joshi, Ryan Antle, Catherine James, Edward Steele, Brian Rovelli
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Publication number: 20180016528Abstract: A method of removing at least a portion of an oxide layer from the surface of a metal substrate comprising exposing the metal substrate to a body of treatment liquor comprising a treatment formulation and a multiplicity of solid particles which comprise or consists of a multiplicity of polymeric particles and wherein said treatment formulation comprises one or more promoters selected from the group consisting of acids, bases and surfactants wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement.Type: ApplicationFiled: March 3, 2014Publication date: January 18, 2018Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Patent number: 9845516Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with an aqueous treatment formulation and a solid particulate material in a sealed apparatus, wherein the aqueous treatment formulation comprises at least one colorant. There is also disclosed an animal substrate obtained by the method and finished leather goods obtained by the method.Type: GrantFiled: April 11, 2014Date of Patent: December 19, 2017Assignee: Xeros LimitedInventor: John Edward Steele
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Publication number: 20170240980Abstract: A method for tanning an animal substrate comprising the steps: i) agitating the animal substrate with a chromium-free tanning agent; and ii) agitating the animal substrate with a tanning agent having an oxazolidine group; wherein at least some of the agitation is performed in the presence of a solid particulate material having an average particle size of from 1 to 500 mm.Type: ApplicationFiled: October 1, 2015Publication date: August 24, 2017Inventors: Addis Duki FEYISA, John Edward STEELE
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Publication number: 20170166841Abstract: Liquid laundry detergent compositions including a polymer including a polyester terephthalate backbone grafted with one or more anionic groups.Type: ApplicationFiled: December 8, 2016Publication date: June 15, 2017Inventors: Lucia FERNANDEZ MARTINEZ, Nigel Patrick SOMERVILLE ROBERTS, Alan Thomas BROOKER, James Edward STEELE CATER
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Publication number: 20160251603Abstract: A method of removing at least a portion of an oxide layer from the surface of a metal substrate comprising exposing the metal substrate to a body of treatment liquor comprising a treatment formulation and a multiplicity of solid particles which comprise or consists of a multiplicity of polymeric particles and wherein said treatment formulation comprises one or more promoters selected from the group consisting of acids, bases and surfactants wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement.Type: ApplicationFiled: March 3, 2014Publication date: September 1, 2016Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Publication number: 20160251602Abstract: A method of cleaning a metal substrate, the method comprising exposing the metal substrate to a body of cleaning liquor comprising a cleaning formulation and a multiplicity of solid particles wherein the method further comprises causing the solid particles and the metal substrate to enter into contacting relative movement; wherein i) the cleaning formulation comprises at least one acid which has a pKa greater than about ?1.7; and/or ii) the cleaning formulation comprises at least one base which has a pKb greater than about ?1.7; and the length of the particles is from about 0.5 mm to about 6 mm.Type: ApplicationFiled: March 3, 2014Publication date: September 1, 2016Applicant: Xeros LimitedInventors: John Edward Steele, Robert Andrew Bird
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Patent number: 9321183Abstract: A thumbpiece or thumb support (400) positioned between a head assembly (300) and a handle assembly (200) of a power operated rotary knife (100). The thumb support (400) includes a thumb supporting surface (454) to support a thumb of an operator's hand during operation of the power operated rotary knife (100). The thumb support (400) comprises a base portion (410) and thumb supporting portion (450) including the thumb supporting surface (454). The thumb support (400) further includes an interface assembly (480) between the thumb supporting portion (450) and the base portion (410) for relative pivotal movement between the thumb supporting portion (450) and the base portion (410).Type: GrantFiled: March 11, 2013Date of Patent: April 26, 2016Assignee: Bettcher Industries, Inc.Inventors: Edward A. Steele, Josiah Brinkerhoff, Tom Remm
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Publication number: 20160040260Abstract: The invention discloses a method for treating an animal substrate comprising: agitating the moistened animal substrate with a treatment formulation and a solid particulate material in a sealed apparatus wherein the treatment formulation comprises a tanning agent or a tannery process agent. The method can comprise applying the tanning agent or tannery process agent to the animal substrate wherein at least some of the agent so applied originates from the treatment formulation. There is also disclosed an animal substrate obtained by the method. The treatment formulation can be aqueous.Type: ApplicationFiled: April 11, 2014Publication date: February 11, 2016Inventor: John Edward STEELE