Patents by Inventor Edward B. Walker
Edward B. Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130078316Abstract: A synthetic endotracheal irrigant for preventing, treating, and reducing infections, including mucosal infections in patients, including infants. A method for producing a formulation of the synthetic endotracheal irrigant with a water content of about 98% (w/w) to about 99.9(w/w) and a total mineral content of less than about 5.0% (w/w), including a sodium content of less than about 2.0% (w/w). The synthetic endotracheal irrigant excludes protein.Type: ApplicationFiled: March 26, 2012Publication date: March 28, 2013Inventors: Robert D. Christensen, Edward B. Walker
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Publication number: 20090324737Abstract: Germicidal compositions with enhanced activity towards killing microbiological spores and vegetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric alcohols, hydrogen peroxide, iodine, triclocarban, triclosan or combinations thereof with one or more spore coat opening agents. The invention also provides for the application of the germicidal compositions to animate and inanimate surfaces to help kill germs and protect against the risk of infection from bacteria, molds, yeasts, fungi, viruses, and microbiological spores.Type: ApplicationFiled: August 13, 2009Publication date: December 31, 2009Inventor: Edward B. Walker
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Patent number: 7192601Abstract: Germicidal compositions with enhanced activity towards killing microbiological spores and vetgetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric alcohols, hydrogen peroxide, iodine, triclocarban, triclosan or combinations thereof with one or more spore coat opening agents. The invention also provides for the application of the germicidal compositions to animate and inanimate surfaces to help kill germs and protect against the risk of infection from bacteria, molds, yeasts, fungi, viruses, and microbiological spores.Type: GrantFiled: January 16, 2003Date of Patent: March 20, 2007Inventor: Edward B. Walker
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Publication number: 20040058878Abstract: Germicidal compositions with enhanced activity towards killing microbiological spores and vetgetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric alcohols, hydrogen peroxide, iodine, triclocarban, triclosan or combinations thereof with one or more spore coat opening agents. The invention also provides for the application of the germicidal compositions to animate and inanimate surfaces to help kill germs and protect against the risk of infection from bacteria, molds, yeasts, fungi, viruses, and microbiological spores.Type: ApplicationFiled: January 16, 2003Publication date: March 25, 2004Inventor: Edward B. Walker
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Patent number: 6440471Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin, leucodelphinin, flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract.Type: GrantFiled: March 30, 2001Date of Patent: August 27, 2002Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mickelsen, Jr., Jennifer N. Mickelsen
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Patent number: 6410039Abstract: A topical composition with silicone oil emulsified in water. The topical composition may be made by diluting a concentrated silicone oil-in-water emulsion with water. The silicone oil of the topical composition and of the concentrated silicone oil-in-water emulsion is suspended in the water by one or more non-ionic surfactants. A combination of non-ionic surfactants may be employed. The topical composition may also include a blend of preservatives, which may be selected to have a synergistic effect. The silicone oil constitutes about 35% of the weight of the concentrated silicone oil-in-water emulsion. The non-ionic surfactant or surfactants make up about 3.5% of the weight of the concentrated oil-in-water emulsion. The diluted topical composition may contain silicone oil in amounts of about 0.1 to about 35%, preferably less than 3% down to about 1%, and more preferably about 1 to about 2% of the weight of the topical composition.Type: GrantFiled: September 15, 1999Date of Patent: June 25, 2002Assignee: First Scientific, Inc.Inventor: Edward B. Walker
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Publication number: 20020028260Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin, leucodelphinin, flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. Coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract.Type: ApplicationFiled: August 1, 2001Publication date: March 7, 2002Inventors: Edward B. Walker, Richard A. Mickelsen, Jennifer N. Mickelsen
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Publication number: 20010021398Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin, leucodelphinin, flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract.Type: ApplicationFiled: March 30, 2001Publication date: September 13, 2001Inventors: Edward B. Walker, Richard A. Mickelsen, Jennifer N. Mickelsen
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Patent number: 6210681Abstract: Compounds isolated from plant materials, particularly plants of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, and an extract of such plant materials which is significantly enriched for the anti-adhesion activity. The specific compounds include procyanidins (also known as “condensed tannins”), leukocyanin and leucodelphinin, and flavonol glucosides including myricetin-3-pyranoside and proanthocyanidin extracts. These proanthocyanidin extracts are capable of inhibiting agglutination reactions of P-type E. coli. The extracts containing proanthocyanidins contain at least one A-type interflavanoid bond. Methods of making an extract having the properties.Type: GrantFiled: September 7, 1999Date of Patent: April 3, 2001Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mickelsen, Jr., Jennifer N. Mickelsen
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Patent number: 5650432Abstract: Proanthocyanidin monomers, dimers, polymers, flavonoid, and flavanoid derivatives and related compounds are used for their ability to interfere with bacterial adherence to a surface. Crystalline proanthocyanadin dimer and plant extracts enriched with such compounds are also disclosed.Type: GrantFiled: March 24, 1995Date of Patent: July 22, 1997Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mickelsen, Jr., Jennifer N. Mickelsen
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Patent number: 5646178Abstract: Compounds isolated from plant materials of the genus Vaccinium, which have biological activity measurable as inhibition with adhesion of bacterial cells to surfaces, are described. The specific compounds include procyanidins, leucocyanin and leucodelphinin, and flavonol glucosides including myricetin-3-pyranoside. An exemplary procyanidin compound is a substituted epicatechin-catechin dimer or other polymer. Also described is an extract prepared from plants of the genus Vaccinium, especially cranberries, which is enriched for anti-adhesion activity. The extract is enriched for polyphenol and flavonoid compounds, lacks detectable amounts of simple sugars, has a very low content of benzoic acid relative to raw cranberries, and lacks significant amounts of anthocyanins. Methods for preparing and for using the extract are disclosed.Type: GrantFiled: June 7, 1995Date of Patent: July 8, 1997Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mickelsen, Jr., Jennifer N. Mickelsen
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Patent number: 5574232Abstract: A flow-through sample cell operable in conjunction with a reflectance or fluorescence spectroscopy apparatus to permit real-time analysis of a liquid sample stream is disclosed. The flow-through sample cell includes a housing and a conical-shaped flow control body positioned within the hollow interior of the housing. A liquid sample stream to be analyzed is introduced into the housing along a flow path tangential to the outer surface of the flow control body so as to cause the liquid sample stream to flow through centrifugal action radially along the outer surface of the conical-shaped flow control body and into a viewing area at the bottom of the sample cell. As the liquid sample stream flows through the viewing area, a real-time analysis of the liquid sample stream may be made by an analyzer device positioned outside the sample cell and adjacent to the viewing area.Type: GrantFiled: June 1, 1995Date of Patent: November 12, 1996Assignees: Robert Davidson, Edward WalkerInventors: Robert A. Davidson, Edward B. Walker
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Patent number: 5525341Abstract: An extract prepared from plants of the genus Vaccinium, especially cranberries, which is enriched for an activity which inhibits bacterial adhesion to surfaces. The extract is also enriched for polyphenol and flavonoid compounds, lacks detectable amounts of simple sugars, has a very low content of benzoic acid relative to raw cranberries, and lacks significant amounts of anthocyanins. Methods for preparing and for using the extract are also disclosed.Type: GrantFiled: February 1, 1994Date of Patent: June 11, 1996Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mickelsen, Jr., Jennifer N. M. Ickelsen, Brent L. Roth
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Patent number: 5474774Abstract: An extract prepared from plants of the genus Vaccinium, especially cranberries, which is enriched for an activity which inhibits bacterial adhesion to surfaces. The extract is also enriched for polyphenol and flavonoid compounds, lacks detectable amounts of simple sugars, has a very low content of benzoic acid relative to raw cranberries, and lacks significant amounts of anthocyanins. Methods for preparing and for using the extract are also disclosed.Type: GrantFiled: March 25, 1994Date of Patent: December 12, 1995Assignee: JLB, Inc.Inventors: Edward B. Walker, Richard A. Mikelsen, Jr., Jennifer N. Mickelsen, Brent L. Roth