Abstract: Methods and apparatuses can include generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method can include generating a 3D model of a portion of a patient's oral anatomy that can be used in dental restoration design. Scanning workflows can include scanning physical models of an object to obtain a 3D model. A scanner can scan physical models of a patient's dentition to obtain scans used to generate a 3D model of a patient's dentition.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model. A scanner is provided for scanning physical models of a patient's dentition to obtain scans for generating a 3D model of a patient's dentition.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model. A scanner is provided for scanning physical models of a patient's dentition to obtain scans for generating a 3D model of a patient's dentition.

Abstract: The present disclosure relates to a composition that includes a metal chalcogenide having a surface and a ligand, where the ligand is covalently bound to the surface. In some embodiments of the present disclosure, the metal chalcogenide may be defined by MXz, where Z is between 1 and 3, inclusively, M (a metal) includes at least one of Sc, Zr, Hf, Zr, Ti, Nb, Ta, V, Mo, Cr, Re, W, S, Pt, Fe, Cu, Sb, In, Zn, Cd, P, and/or Mn, and X (a chalcogenide) includes at least one of S, Se, and/or Te.

Abstract: The present disclosure relates to a composition that includes a metal chalcogenide having a surface and a ligand, where the ligand is covalently bound to the surface. In some embodiments of the present disclosure, the metal chalcogenide may be defined by MXz, where Z is between 1 and 3, inclusively, M (a metal) includes at least one of Sc, Zr, Hf, Zr, Ti, Nb, Ta, V, Mo, Cr, Re, W, S, Pt, Fe, Cu, Sb, In, Zn, Cd, P, and/or Mn, and X (a chalcogenide) includes at least one of S, Se, and/or Te.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model. A scanner is provided for scanning physical models of a patient's dentition to obtain scans for generating a 3D model of a patient's dentition.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model.

Abstract: A computer model of a physical object may be formed by registering multiple images of the physical object by using a registration process based on characteristic features of the physical object. Multiple images may be registered by aligning characteristic curves of the physical object that have been identified through imaging. A curve-based registration process may be used in dental applications to register multiple images of a patient's oral anatomy to form a computer 3D model from which a patient-specific dental restoration may be designed.

Abstract: Methods and apparatus are provided for generating computer 3D models of an object, by registering two or more scans of physical models of an object. The scans may be 3D scans registered by a curve-based registration process. A method is provided for generating a 3D model of a portion of a patient's oral anatomy for use in dental restoration design. Also provided are scanning workflows for scanning physical models of an object to obtain a 3D model.

Abstract: The presently disclosed subject matter relates to peptides having binding affinity for glycopeptide antibiotics and methods and compositions for delivering glycopeptide antibiotic to the surface of medical devices. The peptide compositions can comprise a peptide having binding affinity for a surface material of a medical device that is coupled to the peptide having binding affinity for glycopeptide antibiotic. Also provided are methods of applying the peptide compositions to a medical device by contacting the peptide compositions with a surface of the medical device. In addition, kits are provided comprising the peptide compositions.

Abstract: The present invention provides a way to efficiently validate and process requests, such as deletion requests, that affect items having associated objects in a content management system. When the request is received, a timestamp for the item is retrieved. A timestamp for any objects affected by the request are then retrieved and checked against the timestamp for the item. The request is then completed on the item and objects based on the respective timestamps for the item and the objects.

Abstract: Peptides have been identified that bind with high affinity to hair. Peptide-based hair reagents formed by coupling a hair-binding peptide to a benefit agent are described. The peptide-based hair reagents include peptide-based hair conditioners and hair colorants. The peptide-based hair conditioners and hair colorants are comprised of at least one hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively.

Abstract: Peptides have been identified that bind with high affinity to dyed hair. Peptide-based hair reagents formed by coupling a dyed-hair-binding peptide to a benefit agent are described. The peptide-based hair reagents include peptide-based hair conditioners and hair colorants. The peptide-based hair conditioners and hair colorants are comprised of a dyed-hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based hair reagents or the dyed-hair-binding peptides may also be used as a protective sealant to improve color retention of dyed hair.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.

Abstract: The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.