Patents by Inventor Edward Biehl

Edward Biehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and Derivatives of 2H-Pyrido (3,2-b)(1, 4) Oxazin 3)4H)-Ones as raf Kinase and LRRK2 Inhibitors
    Publication number: 20120245347
    Abstract: The present invention provides oxazine compounds, method of using and method of making oxazine compounds and its pharmaceutical use.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: SOUTHERN METHODIST UNIVERSITY
    Inventors: Edward A. Biehl, Haribabu Ankati, Sukanta Kamila
  • Quinoxaline Compounds and Derivatives
    Publication number: 20120245352
    Abstract: The present invention provides oxazine compounds, method of using and method of making oxazine compounds and its pharmaceutical use.
    Type: Application
    Filed: March 23, 2012
    Publication date: September 27, 2012
    Applicant: Southern Methodist University
    Inventors: Edward A. Biehl, Haribabu Ankati, Sukanta Kamila
  • USE OF NOVEL NEUROPROTECTIVE 3-SUBSTITUTED INDOLONE COMPOSITIONS
    Publication number: 20100298376
    Abstract: The present invention provides compositions and methods of synthesizing optionally substituted 3-substituted indolin-2-ones and methods to employ the resultant compounds to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such as ischemic stroke.
    Type: Application
    Filed: May 13, 2010
    Publication date: November 25, 2010
    Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, SOUTHERN METHODIST UNIVERSITY
    Inventors: Santosh R. D'Mello, Edward A. Biehl
  • USE OF NEUROPROTECTIVE 3-SUBSTITUTED INDOLONE COMPOSITIONS
    Publication number: 20090264494
    Abstract: The present invention include providing a therapeutically effective amount of a 3-substituted indolin-2-one compositions to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such as ischemic stroke
    Type: Application
    Filed: May 13, 2009
    Publication date: October 22, 2009
    Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, SOUTHERN METHODIST UNIVERSITY
    Inventors: Santosh R. D'Mello, Edward Biehl
  • Identification Of A Nitrilase From B. Japonicum By Rational Genome Mining And Methods Of Use
    Publication number: 20070178575
    Abstract: The present disclosure relates to methods of rational genome mining. A method may include narrowing the number of clones that would otherwise need to be screened and/or identifying a gene with a desired catalytic activity. The disclosure also relates to a nitrile hydrolase from Bradyrhizobium japonicum USDA110 first identified by rational genome mining. In addition, the disclosure relates to nitrilase bll6402 and catalytically active variants capable of converting an ?-hydroxy nitriles, a ?-hydroxy nitrile and/or an ?,?-dinitrile to a carboxylic acid.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 2, 2007
    Inventors: Dunming Zhu, Ling Hua, Edward Biehl, Chandrani Mukherjee