Patents by Inventor Edward C. Dempsey

Edward C. Dempsey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of pulmonary vascular remodeling with neprilysin
    Patent number: 9950044
    Abstract: The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: April 24, 2018
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Edward C. Dempsey
  • Treatment of pulmonary vascular remodeling with neprilysin
    Patent number: 8883144
    Abstract: The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.
    Type: Grant
    Filed: September 1, 2011
    Date of Patent: November 11, 2014
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventor: Edward C. Dempsey
  • Treatment of Pulmonary Vascular Remodeling With Neprilysin
    Publication number: 20120121573
    Abstract: The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.
    Type: Application
    Filed: September 1, 2011
    Publication date: May 17, 2012
    Inventor: Edward C. Dempsey
  • Method of using PKC inhibiting compounds to treat vascular disease
    Patent number: 6228843
    Abstract: A method for treating pulmonary and systemic vascular diseases associated with cardiac hypotrophy, dysfunction or failure that involves the administration of an effective amount of a PKC antagonist to a patient suffering from one of such diseases is disclosed. PKC antagonists are selected from bryostatin derivatives and more preferably from bryostatin-1. The disease states treatable in accordance with the present invention are characterized by alterations in vascular structure, vascular tone, myocardial hypotrophy, dysfunction or failure, idiopathic pulmonary hypertension and chronic hypoxic pulmonary hypertension. Particular formulations include bryostatin-1 in an effective amount to treat one or more of the above-referenced diseases.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: May 8, 2001
    Assignee: University Technology Corporation
    Inventor: Edward C. Dempsey