Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.

Abstract: Systems, methods, and apparatuses for adaptive regeneration of aftertreatment system components. The system may include an aftertreatment system and a controller. The controller is configured to access one or more parameters indicative of an ambient condition, determine a regeneration type of a regeneration process for a component of the aftertreatment system, determine an application in condition, and modify a parameter for the regeneration process for the component of the aftertreatment system. In some instances, the controller initiates the regeneration process. In some instances, the one or more parameters include an ambient air temperature, a reductant tank temperature, or a particulate matter sensor temperature. In some instances, the modified parameter includes a target regeneration temperature, a regeneration duration, a dwell time between regeneration process, a threshold value for the regeneration process, or a minimum regeneration temperature.

Abstract: An apparatus and method for controlling engine start/stop operations based at least in part on considerations relating to the thermal management of an exhaust gas after-treatment system. A control system may monitor and/or predict conditions and/or properties of the after-treatment system, including conditions related to the thermal management of a selective catalytic reduction system and the properties of an exhaust gas stream that has been released from an internal combustion engine and into the after-treatment system. Such conditions may be evaluated in determining whether the thermal management of the after-treatment system is at, or will be in, a condition that may accommodate a start/stop operation of the internal combustion engine with minimal, if any, adverse impact on the thermal management of the after-treatment system. Such an evaluation may, in at least certain situations, provide at least a consideration as to whether to de-activate or activate start/stop operations.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.

Abstract: Systems, methods, and apparatuses for adaptive regeneration of aftertreatment system components. The system may include an aftertreatment system and a controller. The controller is configured to access one or more parameters indicative of an ambient condition, determine a regeneration type of a regeneration process for a component of the aftertreatment system, determine an application in condition, and modify a parameter for the regeneration process for the component of the aftertreatment system. In some instances, the controller initiates the regeneration process. In some instances, the one or more parameters include an ambient air temperature, a reductant tank temperature, or a particulate matter sensor temperature. In some instances, the modified parameter includes a target regeneration temperature, a regeneration duration, a dwell time between regeneration process, a threshold value for the regeneration process, or a minimum regeneration temperature.

Abstract: An apparatus and method for controlling engine start/stop operations based at least in part on considerations relating to the thermal management of an exhaust gas after-treatment system. A control system may monitor and/or predict conditions and/or properties of the after-treatment system, including conditions related to the thermal management of a selective catalytic reduction system and the properties of an exhaust gas stream that has been released from an internal combustion engine and into the after-treatment system. Such conditions may be evaluated in determining whether the thermal management of the after-treatment system is at, or will be in, a condition that may accommodate a start/stop operation of the internal combustion engine with minimal, if any, adverse impact on the thermal management of the after-treatment system. Such an evaluation may, in at least certain situations, provide at least a consideration as to whether to de-activate or activate start/stop operations.

Abstract: Methods and compositions related to promoting hair growth are described.

Abstract: Methods and compositions related to targeting agents to tumor tissue are described.

Abstract: Systems, methods, and computer-readable and executable instructions are provided for providing a universal access device. Providing a universal access device can include storing access data for each of a number RFID readers, wherein each of the RFID readers accepts a particular RFID protocol. Providing a universal access device can also include selecting a particular RFID protocol for one of the number of RFID readers while the universal access device is within an activation zone of the RFID reader. Furthermore, providing a universal access device can include providing the access data for the particular RFID reader via the particular RFID protocol.

Abstract: Methods and compositions related to promoting hair growth are described.

Abstract: Methods and compositions related to targeting agents to tumor tissue are described.

Abstract: The invention is a tank fluid parameter monitoring device with at least one tank having at least one tank fluid parameter, at least one tank fluid parameter sensor, and at least one smart transceiver in communication with at least one tank fluid parameter sensor. The smart transceiver further has a means for determining if at least one tank fluid parameter is within a predetermined range and a means for two-way transceiving at least one tank fluid parameter over wireless telemetry.

Abstract: A computer implemented method of predicting decisions uses the knowledge of one or more individuals. The individuals, referred to as a team, are knowledgeable about the domain in which decisions are being made. The team individually rates the importance of decision criteria they deem relevant. They then rate the extent which multiple problem characteristics are deemed relevant to the decision. The ratings are subjected to automated quantitative analysis for consistency, and the raters may discuss and modify inconsistent ratings if appropriate. Once the ratings are accepted, the raters then rate the decision options against the highest scoring problem characteristics as determined in the initial ratings. After one or more further rounds of consistency evaluations, the highest rated options are selected as the prediction of the decision to made by the adversary.