Patents by Inventor Edward Cochrane

Edward Cochrane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azithromycin derivatives containing a phosphonium ion as anticancer agents
    Patent number: 11560395
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: January 24, 2023
    Inventors: Tim Sparey, Andrew Ratcliffe, David Hallett, Brett Stevenson, Edward Cochrane, Alexandre Froidbise
  • Azithromycin derivatives containing a phosphonium ion as anticancer agents
    Patent number: 11427606
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 30, 2022
    Inventors: Tim Sparey, Andrew Ratcliffe, Brett Stevenson, Franz Lagasse, Edward Cochrane
  • Phosphonium-ion tethered tetracycline drugs for treatment of cancer
    Patent number: 11161862
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: November 2, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Tim Sparey, Andrew Ratcliffe, Edward Cochrane, Brett Stevenson, David Hallett, Franz Lagasse, Gilbert Lassalle, Alexandre Froidbise
  • AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS
    Publication number: 20210261582
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 26, 2021
    Inventors: Tim Sparey, Andrew Ratcliffe, David Hallett, Brett Stevenson, Edward Cochrane, Alexandre Froidbise
  • Triphenylphosphonium-tethered tetracyclines for use in treating cancer
    Patent number: 11098073
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: August 24, 2021
    Assignee: Oxford University Innovation Limited
    Inventors: Tim Sparey, Andrew Ratcliffe, David Hallett, Edward Cochrane, Gilbert Lassalle, Alexandre Froidbise, Brett Stevenson
  • AZITHROMYCIN DERIVATIVES CONTAINING A PHOSPHONIUM ION AS ANTICANCER AGENTS
    Publication number: 20210253616
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and the pharmaceutical formulations comprising said compounds.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 19, 2021
    Inventors: Tim Sparey, Andrew Ratcliffe, Brett Stevenson, Franz Lagasse, Edward Cochrane
  • TRIPHENYLPHOSPHONIUM-TETHERED TETRACYCLINES FOR USE IN TREATING CANCER
    Publication number: 20200131208
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Application
    Filed: April 20, 2018
    Publication date: April 30, 2020
    Inventors: Tim Sparey, Andrew Ratcliffe, David Hallett, Edward Cochrane, Gilbert Lassalle, Alexandre Froidbise, Brett Stevenson
  • PHOSPHONIUM-ION TETHERED TETRACYCLINE DRUGS FOR TREATMENT OF CANCER
    Publication number: 20200123182
    Abstract: This invention relates to compounds that are useful as cancer therapies. The compounds comprise derivatives of tetracycline antibiotics, e.g. doxycycline, having a phosphonium cation tethered to the tetracycline tetracycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
    Type: Application
    Filed: April 20, 2018
    Publication date: April 23, 2020
    Inventors: Tim Sparey, Andrew Ratcliffe, Edward Cochrane, Brett Stevenson, David Hallett, Franz Lagasse, Gilbert Lassalle, Alexandre Froidbise