Patents by Inventor Edward D. Hall

Edward D. Hall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pramipexole as a neuroprotective agent
    Patent number: 5650420
    Abstract: The present invention provides the use of pramipexole as a neuroprotective agent.
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: July 22, 1997
    Assignees: Pharmacia & Upjohn Company, Boehringer Ingelheim International GmbH
    Inventors: Edward D. Hall, Philip F. Von Voigtlander, Frank A. Rohde
  • 11a-hydroxy steroid diester
    Patent number: 4948533
    Abstract: The present invention relates to 21-(3-carboxy-1-oxopropoxy) -17.alpha.-hydroxy-11.alpha.-(3,3-dimethyl-1-oxobutoxy)pregna-1,4-diene-3, 20 dione and pharmaceutically acceptable salts thereof which are useful steroid prodrugs.
    Type: Grant
    Filed: February 16, 1989
    Date of Patent: August 14, 1990
    Assignee: The Upjohn Company
    Inventors: John M. Braughler, Edward D. Hall, Wendell Wierenga, John M. McCall
  • Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments
    Patent number: 4771042
    Abstract: A method of inhibiting angiogenesis in a warm blooded animal which comprises administering to said animal an anti-angiogenic effective amount of a compound of the formula: ##STR1## wherein the dotted line between positions C-1 and C-2 means the presence or absence of a double bond; the .about.bond at C-6 denotes .alpha. or .beta.;wherein R.sub.1 is CH.sub.3 or --C.sub.2 H.sub.5 ;wherein R.sub.2 is H, and R.sub.3 is in the .alpha.-position and is --OH, --O-alkyl(C.sub.1 -C.sub.12), --OC(.dbd.O)alkyl(C.sub.1 -C.sub.12), --OC(.dbd.O)aryl, --OC(.dbd.O)N(R).sub.2, or --OC(.dbd.O)OR.sub.7, wherein aryl is furyl, thienyl, pyrrolyl, or pyridyl wherein each of said hetero moiety is optionally substituted with one or two (C.sub.1 -C.sub.4)-alkyl groups or aryl is --(CH.sub.2).sub.f -phenyl wherein f is 0 to 2 and wherein the phenyl ring is optionally substituted with one to three groups selected from chlorine, fluorine, bromine, alkyl(C.sub.1 -C.sub.3), alkoxy(C.sub.1 -C.sub.3), thioalkoxy(C.sub.1 -C.sub.3), Cl.sub.
    Type: Grant
    Filed: January 24, 1986
    Date of Patent: September 13, 1988
    Assignee: The Upjohn Company
    Inventors: John M. Braughler, Edward D. Hall, John M. McCall, Wendell Wierenga, Judah Folkman
  • Use of high doses of derivatives of 6.alpha.-methylprednisolone for the acute treatment of stroke syndrome
    Patent number: 4554271
    Abstract: Use of water soluble 21-dibasic esters of 1-dehydro-6.alpha.-methylhydrocortisone for the acute treatment of stroke syndrome in humans.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: November 19, 1985
    Assignee: The Upjohn Company
    Inventors: J. Mark Braughler, Edward D. Hall