Patents by Inventor Edward Daniel Savory
Edward Daniel Savory has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220348577Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: ApplicationFiled: March 2, 2021Publication date: November 3, 2022Inventors: Giles Brown, Michael Higginbottom, Alison Stewart, Lee Patient, Allison Carley, Iain Simpson, Edward Daniel Savory, Kathryn Oliver, Andrew Graham Cole
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Patent number: 10995091Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: GrantFiled: October 22, 2018Date of Patent: May 4, 2021Assignee: Proximagen LLCInventors: Edward Daniel Savory, Alison Stewart, Allison Carley, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Publication number: 20190062333Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: ApplicationFiled: October 22, 2018Publication date: February 28, 2019Applicant: Proximagen, LLCInventors: Edward Daniel SAVORY, Alison STEWART, Allison CARLEY, Giles BROWN, Iain SIMPSON, Kathryn OLIVER, Lee PATIENT, Michael HIGGINBOTTOM, Andrew Graham COLE
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Patent number: 10155761Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: GrantFiled: April 26, 2017Date of Patent: December 18, 2018Assignee: PROXIMAGEN, LLCInventors: Edward Daniel Savory, Alison Stewart, Allison Carley, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Publication number: 20170226106Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: ApplicationFiled: April 26, 2017Publication date: August 10, 2017Inventors: Edward Daniel Savory, Alison Stewart, Allison Carley, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Patent number: 9353086Abstract: Disclosed are compounds that are antagonists of the CXCR4 receptor.Type: GrantFiled: October 13, 2011Date of Patent: May 31, 2016Assignee: Proximagen LimitedInventors: Edward Daniel Savory, Alison Stewart, Allison Carley, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Publication number: 20160046606Abstract: The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.Type: ApplicationFiled: September 14, 2015Publication date: February 18, 2016Inventors: Edward Daniel Savory, Alison Stewart, Allison Carley, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Patent number: 8633318Abstract: The present invention relates to compounds of formula (I), and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of SSAO activity is beneficial, such as such as inflammatory diseases and immune disorders.Type: GrantFiled: September 16, 2009Date of Patent: January 21, 2014Assignee: Proximagen LtdInventors: Edward Daniel Savory, Iain David Simpson
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Publication number: 20130324556Abstract: A compound of formula (I) or a pharmaceutically acceptable salt, solvate, or hydrate thereof Wherein Y, Z, R3, U, R4, m and n are as defined in the claims.Type: ApplicationFiled: January 27, 2012Publication date: December 5, 2013Inventors: Joe William Boyd, Paul Meo, Michael Higginbottom, Iain Simpson, David Mark Mountford, Edward Daniel Savory
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Publication number: 20130289020Abstract: Disclosed are compounds that are antagonists of the CXCR4 receptor.Type: ApplicationFiled: October 13, 2011Publication date: October 31, 2013Applicant: Proximagen LimitedInventors: Edward Daniel Savory, Allson Stewart, Allison Cartey, Giles Brown, Iain Simpson, Kathryn Oliver, Lee Patient, Michael Higginbottom, Andrew Graham Cole
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Publication number: 20130252951Abstract: The compounds of formula (I) are antagonists of the CCR2 receptor Wherein R1-7 and A are as defined in the claims.Type: ApplicationFiled: September 26, 2011Publication date: September 26, 2013Applicant: Proximagen LimitedInventors: Joe William Boyd, Paul Meo, Michael Higginbottom, Iain Simpson, David Mountford, Edward Daniel Savory
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Publication number: 20120302583Abstract: The present invention relates to a method for the treatment or prevention of inflammation, an inflammatory disease, an immune or an autoimmune disorder, which comprises administering to a mammal in need of such treatment an effective amount of a compound compound of formula (I), and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity.Type: ApplicationFiled: August 6, 2012Publication date: November 29, 2012Applicant: PROXIMAGEN LIMITEDInventors: Edward Daniel Savory, Michael Higginbottom, Kathryn Oliver, Viet-Anh Anne Horgan
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Patent number: 8263616Abstract: The present invention relates to compounds of formula (I), and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.Type: GrantFiled: September 16, 2009Date of Patent: September 11, 2012Assignee: Proximagen LtdInventors: Edward Daniel Savory, Michael Higginbottom, Kathryn Oliver, Viet-Anh Anne Horgan
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Publication number: 20120010188Abstract: The invention relates to compounds of formula (I): and their pharmaceutically acceptable salts and solvates, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.Type: ApplicationFiled: December 4, 2009Publication date: January 12, 2012Applicant: PROMIMAGEN LTD.Inventors: Marianne Nilsson, Martin Haraldsson, Sofia Henriksson, Rikard Emond, Edward Daniel Savory, Iain David Simpson
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Publication number: 20110207746Abstract: The present invention relates to compounds of formula (I), and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.Type: ApplicationFiled: September 16, 2009Publication date: August 25, 2011Applicant: PROXIMAGEN LIMITEDInventors: Edward Daniel Savory, Michael Higginbottom, Kathryn Oliver, VietAnh Anne Horgan
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Publication number: 20090131651Abstract: Synthesis of 2-substituted adenosines of formula (I) using 2-nitro pentabenzoyl adenosine, or 2-nitro pentaacetyl adenosine, as intermediate is described: Formula (I) wherein R=C1-6 alkoxy (straight or branched), a phenoxy group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3—, cyano, nitro, C1-4 alkyl, or C1-4 alkoxy), a benzyloxy group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3—, cyano, nitro, C1-6 alkyl, or C1-6 alkoxy), or a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3—, cyano, nitro, C1-6 alkyl, or C1-6 alkoxy). The methods provide improved yield and purity of product.Type: ApplicationFiled: December 3, 2004Publication date: May 21, 2009Inventors: Giles Albert Brown, Edward Daniel Savory, Jacqueline Valerie Anne Ouzman, Alison Margaret Stoddart
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Publication number: 20080262214Abstract: A method of synthesis of a 2-substituted adenosine of formula I which comprises converting a compound of formula II to a compound of formula (I), wherein: R is C 1-6 alkoxy (straight or branched), a phenoxy group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy), a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C1_6 alkyl, or C1_6 alkoxy), or a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy); R??H, or a protecting group.Type: ApplicationFiled: December 3, 2004Publication date: October 23, 2008Applicant: CAMBRIDGE BIOTECHNOLOGY LIMITEDInventor: Edward Daniel Savory