Abstract: A system and structure determines when or if a utility cart is entering a restricted geographical area, and can disrupt the ignition of the cart to prevent or at least stop such use. The system can also determine a safe time and location for such ignition disruption. A monitoring device can remotely and reliably monitor the state of charge of the cart's battery, even for carts of a range of different battery energy capacities, rated voltage, and technical makeup, and communicate such information to a computer system. A standalone device can be retrofitted onto an existing golf cart without requiring fundamental changes to the cart's initial construction. The device can include an inexpensive module that can reliably monitor the battery state and implement ignition cutoff without requiring software processing capacity within the module.

Abstract: A system and structure determines when or if a utility cart is entering a restricted geographical area, and can disrupt the ignition of the cart to prevent or at least stop such use. The system can also determine a safe time and location for such ignition disruption. A monitoring device can remotely and reliably monitor the state of charge of the cart's battery, even for carts of a range of different battery energy capacities, rated voltage, and technical makeup, and communicate such information to a computer system. A standalone device can be retrofitted onto an existing golf cart without requiring fundamental changes to the cart's initial construction. The device can include an inexpensive module that can reliably monitor the battery state and implement ignition cutoff without requiring software processing capacity within the module.

Abstract: A smokeable material for inclusion in a smoking article, the material comprising particles or fragments comprising acacia gum, wherein the particles or fragments do not comprise a diluent, flavourant or aerosol generating material; and substantially comprise or consist of acacia gum.

Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.

Abstract: The present disclosure relates to pharmaceutical compositions comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)-benzamide and a polymer, dosage forms comprising the formulation and methods of treating subjects having cancer.

Abstract: The present disclosure relates to pharmaceutical compositions comprising N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)-benzamide and a polymer, dosage forms comprising the formulation and methods of treating subjects having cancer.

Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.

Abstract: A pharmaceutical composition comprises multiparticulates comprising a melt-congeal core and a solid amorphous dispersion layer of a poorly water soluble drug and polymer. The multiparticulates are suitable for improving bioavailability of poorly water soluble drugs. The melt-congeal cores facilitate application of the solid amorphous dispersion layer, and allow incorporation of additional optional components to the core so as to adjust the release of drug from the multiparticulate.

Abstract: There is provided a solid aerosol generating material including about 5-35 wt % tobacco extract; about 50-80 wt % filler; about 10-35 wt % aerosol generating agent; and about 2.5-10 wt % binder; wherein weight percentage is calculated on a dry weight basis.

Abstract: A method of producing a smoking article is disclosed. The smoking article comprises a smoke constituent reducing technology which is capable of reducing the concentration of a smoke constituent generated by a smoking article in use. The method comprises in a first step, determining one or more first lateral regions at which, when the smoking article is in use, the smoke constituent is present at a first concentration, and one or more second lateral regions at which, when the smoking article is in use, the smoke constituent is present at a second concentration which is lower than the first concentration. In a second step, the method comprises producing a smoking article in which the smoke constituent reducing technology is targeted to reduce the concentration of the smoke constituent present at the one or more first lateral regions.

Abstract: The present invention relates to a cellulosic material having one or more smoke diluents within its cellular structure and, optionally, one or more smoke diluents on its surface.

Abstract: The present invention relates to a cellulosic material having one or more smoke diluents within its cellular structure and, optionally, one or more smoke diluents on its surface.

Abstract: The invention provides an aerosol generating material (6) for a smoking article, comprising particles (1) that consist essentially of diluent (2) encapsulated by barrier material (3).

Abstract: A pharmaceutical composition comprises multiparticulates comprising a drug, a matrix material, and swelling agent. In one aspect, the multiparticulates comprise a core comprising a drug, and a coating surrounding the core. The coating is selected from the group consisting of (i) a water-permeable, substantially drug-impermeable coating, and (ii) an anti-enteric coating.

Abstract: The invention provides an aerosol generating material (8) for a smoking article (5), comprising particulate porous material impregnated with a diluent (3), wherein said particulate porous material has a BET specific surface area of at least 1200 m2/g. The invention also provides an aerosol generating material (8) for a smoking article (5), comprising particulate calcium carbonate (1) carrying and/or impregnated with a diluent (3).

Abstract: The invention provides an aerosol generating material (6) for a smoking article, comprising particles (1) that consist essentially of diluent (2) encapsulated by barrier material (3).

Abstract: A smoking article can comprise a rod of smokeable material and a first sheet material comprising at least one diluent. The diluent is present in an amount effective to dilute emissions from the rod of smokeable material during combustion.

Abstract: The invention relates to smokable filler materials and a process for making same, the smokable filler material comprising a foaming agent, an agent capable of forming chemical cross-linkages, and a cross-linking agent. A combination of the foaming agent in the foamed state thereof, the agent capable of forming chemical crosslinkages and the cross-linking agent provides a stabilized, foamed material. The invention also provides a smoking article incorporating the smokable filler material of the invention.

Abstract: The invention relates to smokable filler materials and a process for making same, the smokable filler material comprising a foaming agent, an agent capable of forming chemical cross-linkages, and a cross-linking agent. A combination of the foaming agent in the foamed state thereof, the agent capable of forming chemical crosslinkages and the cross-linking agent provides a stabilised, foamed material. The invention also provides a smoking article incorporating the smokable filler material of the invention.

Abstract: Systems and methods for facilitating welding system diagnostics is provided. The invention includes a welder, a local system, a remote system, and/or an alarm component. The invention further provides for receiving sensor input(s), performing test sequence(s) based, at least in part, upon the sensor input(s), performing internal diagnostics, and/or initiating corrective action. The invention further provides for determining a health status of the welder and communicating the health status of the welder to the local system, the remote system and/or the alarm component. The health status of the welder can include welder alarm(s) and/or fault(s). Information regarding the health status of the welder can be sent by telephone, voicemail, e-mail and/or beeper. The welder can communicate with the local system and/or remote system to schedule maintenance. The invention further provides for an expert component to facilitate welding diagnostics.