Abstract: A model (e.g., mechanical computer-aided design (MCAD) model) representing an assembly is displayed in a graphical user interface (GUI). The assembly contains at least a first body and a second body. The physics type of the model is determined in response to an assignment of a physics condition to the first body and/or the second body. Contact-pairs are detected in the model according to the determined physics type. The GUI is updated to indicate where the contact-pairs are located in the model for revision of the contact-pairs. Markers are shown in the GUI to represent corresponding contact-pairs. Markers are logically separated from bodies and faces in the model. The revision of the contact-pairs can be managed with a filtering mechanism either by bodies/faces or by markers.

Abstract: This invention is directed to a method for isolating and/or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.

Abstract: A process for harvesting yew biomass and a process of making Yew pellets from Yew tree material is disclosed herein. The process for harvesting comprising the steps of (i) harvesting the tops or roots of the Yew tree; (ii) washing the harvested material; (iii) drying the harvested material; and (iv) grinding the harvested material into a fine powder. The process for making Yew pellets comprising the steps of (i) adding from about 1% to about 20% w/w water to the Yew tree material; and (ii) compressing the Yew tree material in a die to form a pellet whereby the resulting pellet has a final moisture content of less than 10% by weight. The yew pellets produced herein are suitable for extracting taxane molecules from the pellets.