Patents by Inventor Edward Douglas Brown

Edward Douglas Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkanoic acid 2-quinoline derivatives
    Patent number: 4066651
    Abstract: Novel 1,2-dihydro-2-oxoquinol-4-ylalkanoic acid derivatives bearing a variety of substituents on the quinoline nucleus but including, at position 1, an aromatic radical linked directly or through a C.sub.1-4 -alkylene or a C.sub.2-4 -alkenylene radical. Representative compounds of the invention are 1-(3,4-dichlorobenzyl)-3-methyl-1,2-dihydro-2-oxoquinol-4-ylacetic acid and .alpha.-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)propionic acid. The compounds possess anti-inflammatory or analgesic properties, or are inhibitors of the enzyme aldose reductase.
    Type: Grant
    Filed: March 1, 1976
    Date of Patent: January 3, 1978
    Assignee: Imperial Chemical Industries Limited
    Inventors: David Robert Brittain, Edward Douglas Brown, Walter Hepworth, Gilbert Joseph Stacey
  • Cyclopentane derivatives
    Patent number: 4004021
    Abstract: The disclosure relates to novel pentanor prostaglandin analogues, for example 15-(5-chloroindan-2-yl)-9.alpha.,11.alpha.,15-trihydroxy-16,17,18,19,20-pe ntanor-5-cis,13-trans-prostadienoic acid and 15-(5-chloroindan-2-yl)-11.alpha.,15-dihydroxy-9-oxo-16,17,18,19,20-pentan or-5-cis,13-trans-prostadienoic acid and the 1-ester and 1-alcohol derivatives thereof, to a process for their manufacture, to compositions containing them, and to their use in a method of inducing luteolysis.
    Type: Grant
    Filed: December 18, 1975
    Date of Patent: January 18, 1977
    Assignee: Imperial Chemical Industries Limited
    Inventors: Jean Bowler, Edward Douglas Brown, Peter Robert Marsham, Edward Raymond Halstead Walker
  • Cyclopentane derivatives
    Patent number: 3953502
    Abstract: The disclosure relates to novel pentanor prostaglandin analogues, for example 15-(5-chloroindan-2-yl)-9.alpha.,11.alpha.,15-trihydroxy-16,17,18,19,20-pe ntanor-5-cis, 13-trans-prostadienoic acid and 15-(5-chloroindan-2-yl)-11.alpha.,15-dihydroxy-9-oxo-16,17,18,19,20-pentan or-5-cis,13-trans-prostadienoic acid and the 1-ester and 1-alcohol derivatives thereof, to a process for their manufacture, to compositions containing them, and to their use in a method of inducing luteolysis.
    Type: Grant
    Filed: January 17, 1974
    Date of Patent: April 27, 1976
    Assignee: Imperial Chemical Industries Limited
    Inventors: Jean Bowler, Edward Douglas Brown, Peter Robert Marsham, Edward Raymond Halstead Walker