Patents by Inventor Edward F. Flow

Edward F. Flow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and antibodies that inhibit platelet adhesion
    Patent number: 5498499
    Abstract: A polypeptide analog capable of immunologically mimicking a linear hGPIIb antigenic determinant expressed when platelet-associated GPIIb-IIIa binds fibrinogen is disclosed. An antibody that immunoreacts with the polypeptide and hGPIIb when hGPIIb is present as a platelet-associated GPIIb-IIIa/fibrinogen complex is also disclosed. Further disclosed are diagnostic systems and methods for assaying fibrinogen-bound platelets in a vascular fluid sample using the polypeptides and/or antibodies of the invention.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: March 12, 1996
    Assignee: The Scripps Research Institute
    Inventors: Edward F. Flow, Mark H. Ginsberg, Joseph C. Loftus