Patents by Inventor Edward G. Niles

Edward G. Niles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prokaryotic expression in eukaryotic cells
    Patent number: 5550035
    Abstract: A transient expression system is disclosed that utilizes bacteriophage RNA polymerase in the presence of a DNA-based cytoplasmic virus to facilitate expression of a foreign gene in the cytoplasm of a eukaryotic cell.A method of expressing a foreign gene in the cytoplasm of a eukaryotic cell is also disclosed which comprises incorporating into the cytoplasm a DNA-based cytoplasmic virus, a suitable carrier comprising a gene for an RNA polymerase which gene is foreign to the carrier and to the cells, and a suitable carrier comprising a functional, cistron including a foreign gene flanked by a promotor sequence which is recognized by the RNA polymerase.
    Type: Grant
    Filed: January 26, 1994
    Date of Patent: August 27, 1996
    Assignee: The Research Foundation of State University of New York
    Inventors: Bernard Moss, F. William Studier, Thomas R. Fuerst, Edward G. Niles