Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) and a network entity may pseudo-randomly generate frequency hopping indexes to support secure communication of sounding reference signals (SRSs). For example, the UE may securely obtain a key associated with communication a set of SRSs via respective portions of system bandwidth for communicating with the network entity. The UE and the network entity may generate a set of frequency hopping indexes using the key. The set of frequency hopping indexes may correspond to the set of SRSs, and each frequency hopping index may indicate a respective portion of the system bandwidth for communication of a corresponding SRS. The UE and the network entity may communicate the set of SRSs in accordance with the set of frequency hopping indexes.

Abstract: The present description provides methods, assays and reagents useful for sequencing proteins. Sequencing proteins in a broad sense involves observing the plausible identity and order of amino acids, which is useful for sequencing single polypeptide molecules or multiple molecules of a single polypeptide. In one aspect, the methods are useful for sequencing multiple polypeptides. The methods and reagents described herein can be useful for high resolution interrogation of the proteome and enabling ultrasensitive diagnostics critical for early detection of diseases.

Abstract: Example shoe manufacturing methods and related computer readable medium for implementing a portion of said manufacturing methods are disclosed herein. In some examples, the method includes placing an upper member about an upper portion of a last, wherein the last is a form for the shoe. In addition, the method includes producing a lasting based on data relating to a foot of a user, and attaching the lasting to the upper member, wherein the lasting extends over a lower portion of the last. Further, the method includes molding a sole onto the lasting and the upper member, and removing the last from the upper member.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: Methods, systems, and devices for wireless communication are described. A user equipment (UE) may monitor a set of time-frequency resources for one or more cell detection signals (CDS) associated with a pseudo-random sequence, where the pseudo-random sequence and the set of time-frequency resources are indicated by an output of a pseudo-random function (PRF) that is based on a timing parameter, a cell identifier (ID), and a shared key. Accordingly, the UE may communicate with a network entity via a cell associated with the cell ID based on receiving the one or more CDS. The UE may also exchange one or more messages with the network entity, and may perform a time calibration procedure based on the one or more messages and a delay threshold of the UE. The one or more messages may indicate an ID of the UE, a cryptographic number, a time interval, or a combination thereof.

Abstract: The present invention relates to guidance during a medical intervention. In order to provide an improved navigation support with a facilitated setup, a system (10) for navigation support is provided. An image data input (12) receives a plurality of acquired 2D X-ray images of a subject's body from different angles. A set of markers, which are visible in X-ray images and which are detectable by a navigation system, is assigned to the subject. A marker detecting arrangement (16) is provided that detects a current spatial location of the markers assigned to the subject. A data processor (14) reconstructs a 3D volume of the subject based on the plurality of 2D X-ray images. At least a part of the markers is arranged outside the volume covered by the reconstructed 3D volume of the subject, while the markers are visible in the 2D X-ray images.

Abstract: A circuit for sharing current between parallel LEDs or parallel strings of LEDs, and a method of use of the same, are disclosed herein. The circuit for sharing current between parallel LED pathways can include a first LED pathway, a first transistor coupled to the first set of LEDs and that can control a first current through the first set of LEDs, and a first measurement node having a first sensed voltage. The circuit can include a second LED pathway, a second transistor coupled to the second set of LEDs and that can control a second current through the second set of LEDs, and a second measurement node having a second sensed voltage. The circuit includes a first differential amplifier and a second differential amplifier, each of which can compare sensed voltage and can apply a voltage to a gate of one of the first and second transistors.

Abstract: This invention provides novel oral dosage forms comprising a hops extract. The oral dosage forms are capable of activating bitter taste receptors expressed in the gastrointestinal tract. The applications include but are not limited to the use of the oral dosage forms for reducing energy intake and/or appetite in a subject.

Abstract: A novel device component in a digital healthcare framework adds context to physiological sensor data, where such context data includes a first unique identifier associated with the device and a second unique identifier associated with the user who the physiological data belongs to. The physiological sensor data along with the context data is then encrypted and transmitted via an encrypted channel to a coordination gateway.

Abstract: A coordination gateway component in a digital healthcare framework receives data from a device component and adds annotations to physiological sensor data, where such annotations include medical/domain code information, clinical validation information, and regulatory compliance information. The annotated data is then sent to a data distribution gateway component of the digital healthcare framework.

Abstract: A novel set of graphical user interfaces are used in combination with a data distribution gateway component in a digital healthcare framework, wherein the data distribution gateway stores physiological sensor data enhanced with contextual data, where such contextual data comprises a physiological sensor data point generated at a device component, a user ID that was added by the device component, a device ID that was added by the device component, a timestamp that was added by device component, medical/code annotation data added by a coordination gateway, clinical validation annotation data added by the coordination gateway, and regulatory compliance annotation data added by the coordination gateway.

Abstract: A novel data distribution gateway component in a digital healthcare framework stores physiological sensor data enhanced with contextual data, where such contextual data comprises a physiological sensor data point generated at a device component, a user ID that was added by the device component, a device ID that was added by the device component, a timestamp that was added by device component, medical/code annotation data added by a coordination gateway, clinical validation annotation data added by the coordination gateway, and regulatory compliance annotation data added by the coordination gateway.

Abstract: This invention provides novel oral dosage forms comprising a hops extract. The oral dosage forms are capable of activating bitter taste receptors expressed in the gastrointestinal tract. The applications include but are not limited to the use of the oral dosage forms for reducing energy intake and/or appetite in a subject.

Abstract: A tool, e.g. a downhole tool, utilizes at least one actuator which may be actuated rapidly between positions during operation of the tool. The actuator is moved via flow of an actuating fluid controlled by a main valve which, in turn, is controlled via a pilot valve. The pilot valve is operated to selectively control flow of the actuating fluid to the main valve so as to shift the main valve between desired operational positions.

Abstract: A downhole steering system includes a substantially tubular housing, a shaft positioned within the substantially tubular housing, a first bearing and a second bearing, the first and second bearings being configured to support rotation of the shaft relative to the housing. The first bearing, the second bearing, the shaft, and the housing at least partially define a chamber therebetween. The system also includes at least one structure positioned axially between the first and second bearing and being configured to extend from an exterior of the housing in response to pressure communicated to the chamber.

Abstract: A downhole transducer assembly capable of being safely operated at a variety of pressures and depths may include a turbine rotatable by a fluid pressure differential rotationally fixed to a rotor in a generator. To reduce the rotational speed of the turbine and rotor, a pressure regulator may limit a fluid pressure differential by controlling the volumetric flow. One or more nozzles may be configured to automatically regulate a nozzle diameter, and therefore the pressure drop across the nozzle. A surge protector may be connected to the generator.

Abstract: A downhole tool includes a housing and a housing chamber. The housing chamber is separated from a fluid chamber by a seal. The seal maintains a pressure differential between the housing chamber and the fluid chamber. A pressure adjuster between the housing chamber and the fluid chamber maintains the pressure differential below a maximum pressure differential.

Abstract: A pressure pulse generator and an RSS may change the pressure of a fluid flow through a BHA. If the dogleg at the BHA is less than a target dogleg, then the pressure pulse generator goes into pass-through mode to increase the pressure at the RSS and thereby increase a pad force of the RSS steering pads, increasing the severity of the dogleg. If a downhole tool is stuck, then the pressure pulse generator and the RSS are simultaneously actuated to unstick the downhole tool. The RSS is used to generate and transmit pressure pulses to a downhole tool.

Abstract: Aspects of the disclosure relate to a system including an implement (e.g., a steering tool, a drill bit) tetherable to an equipment string (e.g., a drill string), where the implement includes a steering mechanism to steer the equipment string with respect to a wall of a tubular passage (e.g., a borehole). The system can also include a bearing housing for the equipment string (e.g., connectable to a drill pipe of the drill string), where the bearing housing is rotationally coupled with the implement and rotated. The system can further include an actuation mechanism coupleable between the bearing housing and the steering mechanism to actuate the steering mechanism based upon a rotational orientation of the bearing housing with respect to the steering mechanism.