Abstract: Sensors including a functional component, methods for making such sensors and methods for using sensors including a functional component for the detection of free radical forming compounds including peroxides and devices incorporating such sensors are provided herein.

Abstract: An explosive and narcotics detection system using an ion mobility spectrometer detects the presence of vapor or trace particles of target chemicals. The calibration of the spectrometer depends in part on the stability of a calibrant chemical that may be periodically injected together with sample gas into the ionization region of the spectrometer. The calibrant chemical produces a signal with a drift time that is known relative to target chemicals and may be used to calibrate the expected target chemical drift times. A new calibrant chemical, 5-nitrovanillin, is disclosed for this purpose.

Abstract: An intraocular lens for providing accommodative visions to a subject includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises an optical axis, a central zone disposed about the optical axis, and an annular zone surrounding the central zone. The optic may also comprise additional annular zones disposed about the central zone and the first annular zone. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power, preferably at least about 2 Diopters greater than the base optical power. In some embodiments, the add optical power is at least 3 Diopters, or even 4 Diopters, greater than the base optical power.

Abstract: Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. After the natural crystalline lens has been surgically removed, a flexible ring may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag. The ring is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring has a central component that changes shape as the ring is compressed. The shape change is generally correlated to the size of the capsular bag and may be measured visually or with a camera through the cornea, the measurement being generally independent of corneal magnification.

Abstract: The present invention relates to methods and apparatus to improve human ophthalmic surgery patient wellness and surgical procedural outcome of both indicated cataract surgery and elective surgeries with the implantation of permanent standard intraocular lens (IOL) and new technology intraocular lens (NTIOL). The present invention further relates to measurement of refraction intra-operatively to validate or obviate the pre-operative calculations and thus selection of the IOL or NTIOL and allow for a correction to be made intra-operatively before the permanent IOL or NTIOL is implanted. Specifically, several embodiments of the invention pertain to a disposable, temporary Proxy Lens apparatus that are used for in situ refractive measurements, an Insertion Tool apparatus to manipulate the Proxy Lens within the optical path for the refractive measurement and a Refractometer apparatus to perform the refractive measurements.

Abstract: An intraocular lens for placement into the anterior chamber of a human eye having an optic with a central axis, an anterior surface and a posterior surface. At least one of the surfaces is a rotationally symmetric shaped surface with a center of curvature on the central axis and an 10 aspheric portion formed in a peripheral area of the spherically shaped surface. An attachment mechanism fastens the intraocular lens between the iris and the cornea.