Abstract: The present disclosure relates to a winding for an electrical machine. The winding comprises at least one flat conductor having at least one turn to form the winding, and the at least one flat conductor comprises a substantially L-shaped, U-shaped or V-shaped cross-section. The present disclosure also relates to an electrical machine that includes the winding and an aircraft that includes the electrical machine.

Abstract: A printed circuit board includes a circuit layer with an electrical conductor for conducting electricity through the printed circuit board and a support layer for supporting the circuit layer. The support layer include a fibre-reinforced epoxy layer having a thermally conductive and electrically insulating filler powder embedded therein. The support layer has a thermal conductivity of at least 1 W/m.K.

Abstract: The invention provides a method of detecting a target polynucleotide in a sample comprising: (a) contacting the sample with a guide polynucleotide that binds to a sequence in the target polynucleotide and a polynucleotide-guided effector protein, wherein the guide polynucleotide and polynucleotide-guided effector protein form a complex with any target polynucleotide present in the sample; (b) contacting the sample with a membrane comprising a transmembrane pore: (c) applying a potential to the membrane; and (d) monitoring for the presence or absence of an effect resulting from the interaction of the complex with the transmembrane pore to determine the presence or absence of the complex, thereby detecting the target polynucleotide in the sample.

Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.

Abstract: Provided herein are methods of characterising a target polypeptide as it moves with respect to a nanopore. Also provided are related kits, systems and apparatuses for carrying out such methods.

Abstract: Methods and system for a unique coding framework used to create, manage and track instructions for documentation and dissemination of instructions, indicate a particular association or activate a given process. In one example, the present disclosure relates to the online publishing of documentation to demonstrate relationships of parties and compliance with regulatory and other requirements. The present disclosure uses URL hyperlinks, badges, watermarks, icons and visual displays that are representative of a given function and that may be identified by reference of unique coding structure. The present disclosure relates to the publishing and display of relevant visual codes or images for viewing by members of the public, (human readable) as well as machines. The present disclosure enables the tracking and measurement of uses of coded representations in public or private channels. Structured hyperlink codes allow brief messages to be sent in shortened form to instruct or deliver messages or processes.

Abstract: A processor may identify an anomaly in one or more communications. A processor may monitor the one or more communications for an utterance. A processor may perform natural language processing (NLP) on the utterance. A processor may generate an understanding of the utterance using natural language understanding (NLU). A processor may detect the anomaly from the understanding of the utterance. A processor may execute a response, responsive to detecting the anomaly.

Abstract: The invention provides a method of selectively characterising polynucleotides of a desired property, such as length, using a nanopore, based on the translocation of the polynucleotide through or across the nanopore. Kits and systems for use in such methods are also provided. The methods of the invention are particularly suitable for sequencing polynucleotides such as DNA.

Abstract: Provided are a method, system, and computer program product in which operations are performed to receive a question that includes a descriptor and an indication that indicates that a unique answer to the question is expected. A determination is made of instances of matching descriptors and descriptor targets from a set of documents. The determined descriptor targets are compared for consistency. In response to determining that the determined descriptor targets are inconsistent, more restrictive descriptors are iteratively generated via a selection model based on metadata associated with the question until the descriptor targets are consistent. An answer to the question is returned from consistent descriptor targets.

Abstract: A method for adjusting device system settings in response to analysis of displayed content. In some embodiments, a processor may extract content from contents displayed on a screen of a device. The processor may analyze features of the content. The processor may classify the content as belonging to a content class, based on analysis of the content features, utilizing a machine learning model. The processor may update the device system settings based on the content class.

Abstract: The invention provides a method of detecting a target polynucleotide in a sample comprising: (a) contacting the sample with a guide polynucleotide that binds to a sequence in the target polynucleotide and a polynucleotide-guided effector protein, wherein the guide polynucleotide and polynucleotide-guided effector protein form a complex with any target polynucleotide present in the sample; (b) contacting the sample with a membrane comprising a transmembrane pore; (c) applying a potential to the membrane; and (d) monitoring for the presence or absence of an effect resulting from the interaction of the complex with the transmembrane pore to determine the presence or absence of the complex, thereby detecting the target polynucleotide in the sample.

Abstract: An embodiment for expanding a search query is provided. The embodiment may include receiving a stopping criterion for stopping a search. The embodiment may also include receiving an initial search query. The embodiment may further include submitting the initial search query to an information retrieval system. The embodiment may also include identifying enrichment terms from the retrieved initial set of documents. The embodiment may further include generating a subsequent search query that includes one or more enrichment terms from the retrieved initial set of documents. The embodiment may also include submitting the subsequent search query to the information retrieval system. The embodiment may further include determining whether the stopping criterion is met, and in response to determining the stopping criterion is not met, iterating identifying, generating, submitting steps until the stopping criterion is met.

Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.

Abstract: Provided herein is a method of moving a double-stranded polynucleotide with respect to a nanopore using a motor protein. The method allows a portion of the polynucleotide to be interrogated by the pore multiple times. Also provided are polynucleotide adapters and kits comprising such adapters. The methods find use in characterising polynucleotides, for example in sequencing.

Abstract: A stator core for an electric machine includes a stator tooth for mounting an electromagnetic coil and a cooling structure associated with the stator tooth. The cooling structure has multiple sections adjacent each other along a direction parallel to the axis of the stator core. Each section includes multiple channels for the flow of a coolant. The plurality of channels are spaced azimuthally from each other and are arranged asymmetrically about the stator tooth. Adjacent sections of the cooling structure along the axis of the stator core are substantially identical to each other and are rotated 180 degrees about a radial direction relative to each other.

Abstract: A stator for an electrical machine includes: an annular housing extending around a central axis (X-X); a first circumferential flow channel extending around the housing; a second circumferential flow channel axially spaced from the first circumferential flow channel and extending around the housing; and a plurality of windings. The plurality of windings are circumferentially spaced about the housing to form a passage between each two adjacent windings. Each passage is in fluid communication with both the first circumferential flow channel and the second circumferential flow channel. The first circumferential flow channel is closed to flow at a first circumferential location and the second circumferential flow channel is closed to flow at a second circumferential location, removed from the first circumferential location so as to form a first set of passages (S1) connected in parallel and a second, separate set of passages (S2) connected in parallel.

Abstract: The present disclosure relates to a winding for an electrical machine. The winding comprises at least one flat conductor having at least one turn to form the winding, and the at least one flat conductor comprises a substantially L-shaped, U-shaped or V-shaped cross-section. The present disclosure also relates to an electrical machine that includes the winding and an aircraft that includes the electrical machine.

Abstract: A stator is described herein comprising a first longitudinally extending slot having a cavity defined by a first inwardly facing longitudinal surface and a second inwardly facing longitudinal surface; said stator further comprising a spacer provided in said cavity of said first slot, said spacer comprising a first spacer component that comprises a first sheet of material having a first sheet surface facing inwardly into said slot and an opposite sheet surface that is in contact with and extends along the first longitudinally extending inner surface of said slot and wherein said inwardly facing first sheet surface of said first spacer component comprises at least one ridge projection extending along its length L. Methods for assembling such stators are also described.

Abstract: Provided herein are methods of characterising a target polypeptide as it moves with respect to a nanopore. Also provided are related kits, systems and apparatuses for carrying out such methods.

Abstract: The present disclosure provides processes for producing images with toner particles. In embodiments, toner particles of a certain diameter in size are applied to a substrate as an incomplete monolayer, and then fused to form an image that is a complete monolayer and possesses a thickness less than the diameter of the particles utilized to form the image.