Abstract: Embodiments of the present disclosure include, for example, systems, apparatuses, devices, and methods for producing a population of particles. In some embodiments, such particles include particles corresponding to an active, pharmaceutical ingredient.

Abstract: Disclosed is systems and methods for cleaning devices holding fluid such as heat exchanges. The cleaning is performed by using a system such as a transducer assembly including a mechanical wave generator and a waveguide including a cavity. The system is capable of operating at its fundamental resonance frequency even when connected to an outer surface of the device to be cleaned.

Abstract: Embodiments of the present disclosure include, for example, systems, apparatuses, devices, and methods for producing a population of particles. In some embodiments, such particles include particles corresponding to an active, pharmaceutical ingredient.

Abstract: Embodiments of the present disclosure include, for example, systems, apparatuses, devices, and methods for producing a population of particles. In some embodiments, such particles include particles corresponding to an active, pharmaceutical ingredient.

Abstract: Various embodiments are described herein for a device for using acoustic or mechanical energy to perform an action at a target site of an object. The device comprises a conduit having an aperture disposed at the target site, a displacement signal source for generating a mechanical displacement signal, a coupling assembly having for coupling the displacement signal source to the conduit, a pressure controller coupled to the proximal end of the conduit to vary an amount of pressure in the conduit when obtaining a first entity from or delivering a second entity to the target site, and a control unit for controlling the displacement signal source to generate the mechanical displacement signal based on a desired acoustic or mechanical wave mode.

Abstract: Disclosed is systems and methods for cleaning devices holding fluid such as heat exchanges. The cleaning is performed by using a system such as a transducer assembly including a mechanical wave generator and a waveguide including a cavity. The system is capable of operating at its fundamental resonance frequency even when connected to an outer surface of the device to be cleaned.

Abstract: A system for detecting a wave occurring in/on a membrane includes a source for directing an excitation signal obliquely to the membrane and a receiver for measuring interference between a first part of the excitation signal reflected off a front surface of the membrane and a second part of the excitation signal reflected off a rear surface of the membrane. The system includes a processing device for detecting the wave based on a change in the measured interference. The detection of the wave is based on changes caused by the wave in the optical length of a V-shaped part of a propagation path of the second part of the excitation signal, where the V-shaped part of the propagation path is inside the membrane.

Abstract: Disclosed is methods and systems for cleaning devices holding fluid such as heat exchanges. The cleaning is performed by using a system such as a transducer assembly including at least one pair of protrusions acting as point-like pressure sources or at least one substantially circular protrusion acting as a substantially circular point-like pressure source, coupled to outer surface of the device to be cleaned. Accordingly, coupling of the system to device is reduced, and as a result, the system is able to operate at its fundamental resonance frequency, while the protrusions still permit power delivery to the device.

Abstract: The present invention relates to systems and methods for cleaning of devices, such as heat exchangers. According to the invention, controlled cavitation is created at predetermined positions within a device. The cavitation is done by mechanical waves, such as ultrasound waves, generated by transducers, wherein the waves are based on output of time-reversal wave form analysis of the device structures.

Abstract: The present invention relates to a device exploiting magneto-hydrodynamics (MHD) for localized delivery of material into a target or extraction of material from a target. The device includes a frame (101) comprising a space (102) for conductive fluid and the material, at least one pair of electrodes (103A, 103B) facing each other, a source of electric current (105), a magnet (105), and an opening (106). The electric current and the magnetic field are synchronized so that the material can be moved from the volume between the electrodes through the opening towards the target or from the target through the opening towards the volume. According to the invention the volume is ?2000 mm3, in proviso that mean distance between tips of the electrodes is ?20 mm.

Abstract: Disclosed is a method for producing oleogels by sonicating a mixture including an oleogelator component and an oil component with ultrasound including superpositioned ultrasound waves while cooling the mixture from a temperature wherein the mixture is in molten state to a temperature wherein the oleogelator component of the mixture is at least partially in solid state. The method produces oleogels of improved stability.

Abstract: The application relates to a device (100) for non-invasively sampling interstitial fluid comprising one or more analytes from dermis (101 a) to skin surface (101 b) by using the magneto-hydrodynamic effect. The device comprises a first electrode (102a) and a second electrode (102b) adapted to be positioned adjacent to the skin surface, the first electrode separated from the second electrode by a distance (103), a power source (104) adapted to induce an electric current through the first electrode, the interstitial fluid and the second electrode, and also a magnet (105) adapted to produce a magnetic field to the interstitial fluid. Direction of the magnetic field and direction of the electric current produced by the magnet and the power source, respectively, is such that Lorentz force drives the fluid from the dermis towards the skin surface.

Abstract: An object delivery arrangement is disclosed for delivering objects into bone. The arrangement is configured for generating localized mechanical waves into a tissue, for performing localized deposition of the objects near bone, and for exposing the objects and the bone to said mechanical waves to obtain deposition of the objects into the bone.

Abstract: An intraocular pressure measurement arrangement is disclosed for measuring pressure of an eye of a patient. The arrangement can detect at least one of acoustic reflectivity, optical reflectivity, optical path difference, positioning of intraocular pressure measurement arrangement with respect to the eye, orientation of intraocular pressure measurement arrangement with respect to the eye, shape of cornea and corneal thickness. At least one source can produce acoustic, nonlinear acoustic, mechanical or a nonlinear mechanical wave from a distance, coupling to the eye to generate at least one surface wave. Upon triggering data acquisition, at least one surface wave from a distance from the eye can be detected to extract surface wave information with pressure information of the eye being based on the surface wave information.

Abstract: The object of the invention is a skeletal method utilizing electromagnetic waves to be utilized at least in one of skeletal actuation, skeletal detection and skeletal therapy. In the method is performed at least one of first and second method steps, where in the first method step is generated by means of electromagnetic waves at least one mechanical wave in at least one generation location into the skeleton through soft tissue. In the second method step is detected by means of electromagnetic waves skeletal vibrations due to at least one mechanical wave, is recorded the detected at least one mechanical wave in at least one recording location to form mechanical wave information, and distance of said at least one recording location from said at least one generation location is known, and further in the second method step is determined skeletal properties based on at least one recorded signal.

Abstract: Various embodiments are described herein for a device for using acoustic or mechanical energy to perform an action at a target site of an object. The device comprises a conduit having an aperture disposed at the target site, a displacement signal source for generating a mechanical displacement signal, a coupling assembly having for coupling the displacement signal source to the conduit, a pressure controller coupled to the proximal end of the conduit to vary an amount of pressure in the conduit when obtaining a first entity from or delivering a second entity to the target site, and a control unit for controlling the displacement signal source to generate the mechanical displacement signal based on a desired acoustic or mechanical wave mode.

Abstract: An artifact for improving the vertical resolution of radiation-based imaging is presented. The artifact has a stepped thickness profile with steps. Adjacent steps are arranged to interact differently with radiation used in the radiation-based imaging. Thus, it is possible to identify which step is, in each imaging situation, vertically closest to the imaging plane related to the radiation-based imaging. Thus, a pre-determined vertical position-value related to the closest one of the steps can be used as a vertical position-value related to a radiation-based imaging result obtained in the imaging situation.

Abstract: An arrangement for determining four-dimensional properties of an interface of an object, including a light source includes: a unit for forming photonic jets, a unit for performing large field of view interferometric imaging of the interface and their combination, a unit for passing the light being close to the interface and direct the light to the interface, and an image unit. The arrangement includes a unit for performing phase shifting interferometric imaging of the interface, imaging a unit for receiving light from the interface modulated by e.g. microspheres for forming super-resolution image information by combining light interferometry with the photonic jets, and a processor unit for determining four-dimensional properties of the interface on the basis of the image information formed by the phase shifting interferometric imaging by utilizing effect of the photonic jets. The arrangement also can also include a unit to carry out the measurement using polarized light.

Abstract: The application relates to a device (100) for non-invasively sampling interstitial fluid comprising one or more analytes from dermis (101 a) to skin surface (101 b) by using the magneto-hydrodynamic effect. The device comprises a first electrode (102a) and a second electrode (102b) adapted to be positioned adjacent to the skin surface, the first electrode separated from the second electrode by a distance (103), a power source (104) adapted to induce an electric current through the first electrode, the interstitial fluid and the second electrode, and also a magnet (105) adapted to produce a magnetic field to the interstitial fluid. Direction of the magnetic field and direction of the electric current produced by the magnet and the power source, respectively, is such that Lorenz force drives the fluid from the dermis towards the skin surface.

Abstract: The present invention relates to systems and methods for cleaning of devices, such as heat exchangers. According to the invention, controlled cavitation is created at predetermined positions within a device. The cavitation is done by mechanical waves, such as ultrasound waves, generated by transducers, wherein the waves are based on output of time-reversal wave form analysis of the device structures.