Abstract: Methods for identifying patients with molecular or complete remission of colorectal cancer following therapy a fluorocytidine derivative and a COX-2 enzyme inhibitor by quantifying CD 133 expression levels. Methods for detecting cancer stem cells by quantifying serum CD 133 RNA levels are also provided.

Abstract: A sequence for distributing at least one of a plurality of code packages to the at least one facility according to different states of a fixed state machine is set. The at least one of the plurality of code packages is installed in at least one staging area. The at least one of the plurality of code packages is maintained in the at least one staging area in a valid, dormant mode while the fixed state machine is stopped. Pursuant to a resumption of the fixed state machine at a subsequent time, a current code package is swapped with the at least one of the plurality of code packages in the at least one staging area to activate the at least one of the plurality of code packages.

Abstract: A sequence for distributing at least one of a plurality of code packages to the at least one facility according to different states of a fixed state machine is set. The at least one of the plurality of code packages is installed in at least one staging area. The at least one of the plurality of code packages is maintained in the at least one staging area in a valid, dormant mode while the fixed state machine is stopped. Pursuant to a resumption of the fixed state machine at a subsequent time, a current code package is swapped with the at least one of the plurality of code packages in the at least one staging area to activate the at least one of the plurality of code packages.

Abstract: Various embodiments for automated error recovery in a computing storage environment by a processor device are provided. In one embodiment, if a failure is caused by an operation of a hardware management console (HMC) and a malfunction of a current network connection, a cleanup operation is performed on at least a portion of a current HMC configuration, an alternative network connection to the current network connection is made, and a retry operation is performed.

Abstract: Various embodiments for providing an update to at least one storage facility in a computing storage environment are provided. In one embodiment, media is received in one or more updatable elements of one or more components of the at least one storage facility, each of the one or more updatable elements including one or more unique update images and one or more unique update commands, a security verification is performed on the update via a certificate authentication mechanism to confirm a validity of the update, a safety verification is performed on the update to confirm a suitability of the update to the at least one storage facility, the update is installed in the at least one storage facility, and the update in the at least one storage facility is processed by traversing a fixed state machine for each updatable element.

Abstract: Various embodiments for automated error recovery in a computing storage environment by a processor device are provided. In one embodiment, if a failure is caused by an operation of a hardware management console (HMC) and a malfunction of a current network connection, a cleanup operation is performed on at least a portion of a current HMC configuration, an alternative network connection to the current network connection is made, and a retry operation is performed.

Abstract: Various embodiments for providing an update to at least one storage facility in a computing storage environment are provided. In one embodiment, a security verification is performed on the update via a certificate authentication mechanism to confirm a validity of the update. Subsequent to confirming the validity of the update, a safety verification on the update is performed to confirm a suitability of the update to the at least one storage facility. If the security and safety verifications are validated, the update is provided and installed in the at least one storage facility.

Abstract: A sequence for distributing at least one of a plurality of code packages to the at least one facility according to different states of a fixed state machine is set. The at least one of the plurality of code packages is installed in at least one staging area. The at least one of the plurality of code packages is maintained in the at least one staging area in a valid, dormant mode while the fixed state machine is stopped. Pursuant to a resumption of the fixed state machine at a subsequent time, a current code package is swapped with the at least one of the plurality of code packages in the at least one staging area to activate the at least one of the plurality of code packages.

Abstract: Various embodiments for providing an update to at least one storage facility in a computing storage environment are provided. In one embodiment, a security verification is performed on the update via a certificate authentication mechanism to confirm a validity of the update. Subsequent to confirming the validity of the update, a safety verification on the update is performed to confirm a suitability of the update to the at least one storage facility. If the security and safety verifications are validated, the update is provided and installed in the at least one storage facility.

Abstract: Various embodiments for updating at least one facility in a computing storage environment are provided. In one embodiment, a sequence for distributing at least one of a plurality of code packages to the at least one facility according to different states of a fixed state machine is set. The at least one of the plurality of code packages is installed in at least one staging area. The at least one of the plurality of code packages is maintained in the at least one staging area in a valid, dormant mode while the fixed state machine is stopped. Pursuant to a resumption of the fixed state machine at a subsequent time, a current code package is swapped with the at least one of the plurality of code packages in the at least one staging area to activate the at least one of the plurality of code packages.

Abstract: The present invention provides, in certain embodiments, methods for the treatment of colorectal cancer comprising administering a COX-2 inhibitor and fluorocytidine derivative to a human patient. In certain embodiments, a radiation therapy is also administered to the patient.

Abstract: A two-phase process FlashCopy operation is provided that can be used to aid in the formation of consistency groups across multiple storage control units. In the first phase, preparations to create a new consistency group are made “revertible” by write-inhibiting the source volumes through “Establish-FlashCopy-revertible” commands. If the preparation of any volume within the consistency group fails, a “Withdraw-FlashCopy-revert” command may be executed, thereby causing a retention of the prior FlashCopy point-in-time copy. In the second phase, executed if all preparations are successful, a “Withdraw-FlashCopy-commit” command may be executed to remove all write-inhibit indicators, complete the creation of the new FlashCopy point-in-time copy and secure the new consistency group. Write requests to the FlashCopy source volumes may then be received and processed without risking corruption of the new consistency group on the Flashcopy target volumes.

Abstract: The present invention provides, in certain embodiments, methods for the treatment of colorectal cancer comprising administering a COX-2 inhibitor and fluorocytidine derivative to a human patient. In certain embodiments, a radiation therapy is also administered to the patient.

Abstract: The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis. Therefore, the invention is applied to ascertain the quantity of EPCs in a subject, and to diagnose and monitor angiogenesis, for example, in injured tissues and in cancer development and progression.

Abstract: Methods, system and computer program product are provided to improve the efficiency of data transfers in a PPRC environment. A block of data to be transferred is divided into tracks. Each track is allocated to a data mover task control block (TCB) with a master TCB being assigned to supervise the data mover TCBs. The tracks are then transferred from the primary storage controller to the secondary controller in a piped fashion over a link coupling the primary and secondary storage controllers. However, the usage of resources is monitored by a resource management algorithm and, if too many TCBs are being used for a transfer or if the supply of data mover TCBs is exhausted, the transfer is automatically switched to a serial, non-piped transfer with the master TCB serving as the data mover TCB for the remaining tracks. In addition, the various links coupling the primary and secondary storage controllers is monitored to determine which link will provide the fastest transfer.

Abstract: The present invention involves the use of quantitative RT-PCR to identify AC133 as a marker. AC133 is prevalent on endothelial progenitor cells (EPCs), which are important cells in angiogenesis. Therefore, the invention is applied to ascertain the quantity of EPCs in a subject, and to diagnose and monitor angiogenesis, for example, in injured tissues and in cancer development and progression.