Patents by Inventor Edward H. Walker

Edward H. Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphoinositide 3-kinases
    Patent number: 6890747
    Abstract: The present invention relates PI3K crystals, polypeptide muteins, polypeptide fragments, antibodies thereto, nucleic acids coding for these polypeptides, methods of modifying PI3K? activity, and methods of modulating PI3K? activity. These include polypeptides and methods thereof, relating to, e.g., phospholipid binding, lipid kinase activity, modulating Ras activity in activating the PI3K?, binding of PI3K? to cell membranes, and modulating protein—protein interactions with PI3K?.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: May 10, 2005
    Assignees: Warner-Lambert Company, Onyx Pharmaceuticals, Inc.
    Inventors: Roger Williams, Christian Ried, Edward H. Walker, Len Stephens
  • Phosphoinositide 3-kinases
    Publication number: 20030022344
    Abstract: The present invention relates PI3K crystals, polypeptide muteins, polypeptide fragments, antibodies thereto, nucleic acids coding for these polypeptides, methods of modifying PI3K&ggr; activity, and methods of modulating PI3K&ggr; activity. These include polypeptides and methods thereof, relating to, e.g., phospholipid binding, lipid kinase activity, modulating Ras activity in activating the PI3K&ggr;, binding of PI3K&ggr; to cell membranes, and modulating protein-protein interactions with PI3K&ggr;.
    Type: Application
    Filed: October 9, 2001
    Publication date: January 30, 2003
    Inventors: Roger Williams, Christian Ried, Edward H. Walker, Len Stephens