Abstract: A compound of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with casein kinase 1 delta (CSNK1D) modulation, such as those associated with mood/psychiatric disorders, neurodegenerative diseases, cancers, addiction and substance abuse disorders, pain, and metabolic diseases. Wherein R1, R2, R3, and R4, are defined herein.

Abstract: What is disclosed is a method of operating a wireless communication device. The method includes accessing a wireless access system to receive a communication service, determining a service operator of the wireless access system, and selecting a data rate based on the service operator of the wireless access system. The method also includes requesting the selected data rate for the communication service from the wireless access system, and receiving the communication service at the selected data rate from the wireless access system.

Abstract: A method of operating a wireless communication system includes transmitting a power control code from a wireless access node to each of plurality of wireless communication devices. In each of the plurality of wireless communication devices, the method includes transmitting user communications for receipt by the wireless access node at a first transmit power level as indicated by the power control code. The method also includes transmitting a power mode instruction from the wireless access node to a subset of the plurality of wireless communication devices. In each of the subset of the plurality of wireless communication devices, the method includes transmitting the user communications for receipt by the wireless access node at a second transmit power level as indicated by interpreting the power control code with the power mode instruction.

Abstract: A communication system provides a wireless communication session to a user device over a forward link and a reverse link. A wireless network determines that drop notification and protection is effective for the session and detects session loss on the reverse link. The network transfers a session loss indication to the user device to over the forward link and transfers a protection notice to the other communication end-point. The user device receives the session loss indication over the forward link and notifies the user. The user device transfers recovery probes over the reverse link. The network detects session recovery on the reverse link and transfers a session recovery indication to the user device over the forward link. The network transfers a recovery notice to the communication end-point. The user device receives the session recovery indication over the forward link and notifies the user of the session recovery.

Abstract: Nucleic acids and sequences therefor are disclosed that are characterized by a reduction or lack of internal secondary structure, are capable of hybridizing with a complementary nucleic acid and do not hybridise with non-complementary nucleic acids (eg. do not cross-hybridise or form dimers) under low stringency hybridisation conditions. In particular, the nucleotide sequences enable use of these nucleic acids, without reduction in target hybridisation efficiency with increasing nucleic acid length. The nucleic acids may be used with analyte capture systems, for example medical, veterinary and agricultural diagnostic applications. In particular, the nucleic acid may be used as irrelevant binding pairs in an analyte capture system, such as an array or lateral flow assay.

Abstract: Nucleic acids and sequences therefor are disclosed that are characterized by a reduction or lack of internal secondary structure, are capable of hybridizing with a complementary nucleic acid and do not hybridize with non-complementary nucleic acids (eg. do not cross-hybridize or form dimers) under low stringency hybridization conditions. In particular, the nucleotide sequences enable use of these nucleic acids, without reduction in target hybridization efficiency with increasing nucleic acid length. The nucleic acids may be used with analyte capture systems, for example medical, veterinary and agricultural diagnostic applications. In particular, the nucleic acid may be used as irrelevant binding pairs in an analyte capture system, such as an array or lateral flow assay.

Abstract: A high precision DAC (10) incorporates a low precision DAC (18) and current sources (15(A)-15(O)) whose full-scale currents are adjusted to match a reference current generated by an analog calibration circuit (28). An additional low precision DAC (20) and another current source (16) are spares that allow periodic calibration of the high precision DAC (10) to occur in the background without taking the high precision DAC (10) off-line or out of service. A thermometer code generated by a thermometer code circuit (12) is used by a thermometer mapper circuit (13) to enable the most recently calibrated current sources to generate currents having the highest probability for use by the high precision DAC (10).

Abstract: A temperature compensated low voltage reference that produces an output voltage less than the silicon band-gap voltage. The low voltage reference includes at least a first and a second transistor for providing a voltage independent of variations in the collector power supply and at least a third transistor for developing a voltage that is a fractional value of the base-to-emitter voltage drop of a transistor. The at least a third transistor for developing is coupled with the at least a first and a second transistor for providing. The low voltage reference also includes an output transistor for providing an output voltage. The output transistor is controlled by the voltage provided by the at least a first and a second transistor for providing so that the output voltage is essentially insensitive to temperature variations and is a lower value than the silicon band-gap voltage.

Abstract: An amplifier configuration is disclosed which utilizes a resistive, positive feedback network to develop a high input impedance. The amplifier, which is suitable for manufacture in monolithic integrated circuit form, includes a pair of differential transistors which are coupled to a current supply that provides a current having a predetermined temperature coefficient. A resistor, which is connected between the emitters of the differential transistors, develops either a temperature stable offset voltage or an offset voltage having a desired temperature coefficient in response to the current. A negative feedback circuit facilitates control of the bias voltages for the pair of differential transistors. Temperature stable quiescent input and output voltage levels are derived from the offset voltage through the feedback network.