Patents by Inventor Edward Hawrot

Edward Hawrot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • &agr;-bungarotoxin molecules and uses thereof
    Patent number: 6753315
    Abstract: This invention relates to compositions and methods for the specific inhibition of neurotransmission. More specifically, the invention relates to isolated modified &agr;-bungarotoxin molecules that show high specificity for nicotinic acetylcholine receptors. Such modified &agr;-bungarotoxin molecules, as well as native &agr;-bungarotoxin molecules, are useful in a variety of conditions where localized inhibition of neuronal and/or muscle cell function is desirable.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: June 22, 2004
    Assignee: Brown University Research Foundation
    Inventor: Edward Hawrot
  • Alpha-bungarotoxin molecules and uses thereof
    Publication number: 20030208042
    Abstract: This invention relates to compositions and methods for the specific inhibition of neurotransmission. More specifically, the invention relates to isolated modified &agr;-bungarotoxin molecules that show high specificity for nicotinic acetylcholine receptors. Such modified &agr;-bungarotoxin molecules, as well as native &agr;-bungarotoxin molecules, are useful in a variety of conditions where localized inhibition of neuronal and/or muscle cell function is desirable.
    Type: Application
    Filed: May 29, 2003
    Publication date: November 6, 2003
    Applicant: Brown University Research Foundation
    Inventor: Edward Hawrot
  • Alpha-bungarotoxin molecules and uses thereof
    Publication number: 20020081291
    Abstract: This invention relates to compositions and methods for the specific inhibition of neurotransmission. More specifically, the invention relates to isolated modified &agr;-bungarotoxin molecules that show high specificity for nicotinic acetylcholine receptors. Such modified &agr;-bungarotoxin molecules, as well as native &agr;-bungarotoxin molecules, are useful in a variety of conditions where localized inhibition of neuronal and/or muscle cell function is desirable.
    Type: Application
    Filed: February 23, 2001
    Publication date: June 27, 2002
    Inventor: Edward Hawrot
  • Avidin or streptavidin conjugated liposomes
    Patent number: 4948590
    Abstract: A liposome conjugated with a streptavidin compound, wherein carboxyl residues of the streptavidin are coupled to phospholipid amino groups of the liposome. The resultant streptavidin-conjugated liposome can be used to encapsulate drugs and cytotoxic agents for site-specific in vivo or ex corpra targeting.
    Type: Grant
    Filed: June 9, 1987
    Date of Patent: August 14, 1990
    Assignee: Yale University
    Inventors: Edward Hawrot, Michael B. Rosenberg, Xandra O. Breakefield