Patents by Inventor Edward Htun van der Horst

Edward Htun van der Horst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of her3 activity
    Patent number: 9011851
    Abstract: The present invention relates to a pharmaceutical composition comprising as an active agent an inhibitor of HER3 activity, particularly an anti-HER3-antibody. Further, the use of this composition for the diagnosis, prevention or treatment of hyperproliferative diseases, particularly tumor diseases is disclosed.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: April 21, 2015
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Axel Ullrich, Edward Htun-Van Der Horst
  • Inhibitors of her3 activity
    Publication number: 20040197332
    Abstract: The present invention relates to a pharmaceutical composition comprising as an active agent an inhibitor of HER3 activity, particularly an anti-HER-antibody. Further, the use of this composition for the diagnosis, prevention or treatment of hyperproliferative diseases, particularly tumor diseases is disclosed.
    Type: Application
    Filed: February 9, 2004
    Publication date: October 7, 2004
    Inventors: Axel Ullrich, Edward Htun-van der Horst
  • Pyk2 phosphorylation by her3 induces tumor invasion
    Publication number: 20040082510
    Abstract: The present invention relates to the use of a HER2 protein or a nucleic acid coding therefor as a target for the modulation of the mitogen-activated protein (MAP) kinase pathway. Further, the use of a PYK2 protein and a nucleic acid coding therefor as a target for the modulation of the MAP kinase pathway is described. By inhibiting HER3 kinase activity, the phosphorylation of PYK2 and thus the stimulation of the MAP kinase pathway is inhibited. The present invention is preferably suitable for applications, particularly diagnostic or medical applications, wherein an inhibition of the MAP kinase pathway is desired. Thus, the invention relates to novel methods for diagnosing, treating or preventing MAP kinase associated disorders such as tumors.
    Type: Application
    Filed: July 31, 2003
    Publication date: April 29, 2004
    Inventors: Axel Ullrich, Edward Htun van der Horst