Patents by Inventor Edward J. Cone
Edward J. Cone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210093563Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.Type: ApplicationFiled: October 13, 2020Publication date: April 1, 2021Inventors: Tommy L. CHAU, John M. PINNEY, Jack E. HENNINGFIELD, Edward J. CONE, Saul M. SHIFFMAN, Joseph G. GITCHELL
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Patent number: 10799449Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.Type: GrantFiled: February 4, 2014Date of Patent: October 13, 2020Assignee: JSRNTI, LLCInventors: Tommy L. Chau, John M. Pinney, Jack E. Henningfield, Edward J. Cone, Saul M. Shiffman, Joseph G. Gitchell
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Publication number: 20140154301Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.Type: ApplicationFiled: February 4, 2014Publication date: June 5, 2014Applicant: JSRNTI, LLCInventors: Tommy L. CHAU, John M. PINNEY, Jack E. HENNINGFIELD, Edward J. CONE, Saul M. SHIFFMAN, Joseph G. GITCHELL
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Patent number: 8642016Abstract: A method is provided of making a medicinal delivery system which satiates a craving in an individual when the medicinal delivery system is administered orally to the individual. A coating composition is applied on a saliva-soluble powder to establish a coated powder, the coating composition featuring an at least partially solubilized craving satiation medicinal compound. The coated powder is combined with an edible carrier base to establish a medicinal delivery system that rapidly releases medicine and buffer preferably followed by slower, sustained release.Type: GrantFiled: July 20, 2007Date of Patent: February 4, 2014Assignee: JSRNTI, LLCInventors: Tommy L. Chau, John M. Pinney, Jack E. Henningfield, Edward J. Cone, Saul M. Shiffman, Joseph G. Gitchell
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Publication number: 20080187589Abstract: A multi-modal absorption, medicine-delivery lozenge is provided. The lozenge includes a lozenge base for oral administration into a user's mouth, a medicinal active ingredient including an antihistamine convertible between ionized and non-ionized states, and a buffer present in an effective amount for establishing a pH in the individual's mouth which is characterized by a simultaneous presence of a first pharmacologically effective dose of the non-ionized form of the medicinal active ingredient for transmucosal absorption, and a second pharmacologically effective dose of the ionized form of the medicinal active ingredient for gastro-intestinal absorption.Type: ApplicationFiled: February 5, 2008Publication date: August 7, 2008Inventors: JOHN M. PINNEY, Edward J. Cone, Tommy L. Chau, August R. Buchhalter
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Patent number: 6893654Abstract: A two-stage medicine delivery system provides an initial dose of medicine and a second dose of medicine. The initial and second doses are capable of achieving a rapid pharmacological effect and a prolonged pharmacological effect, respectively. The two-stage medicine delivery system preferably delivers a craving reduction substance, in which case, the rapid and prolonged pharmacological effects include a rapid and prolonged craving reduction. Preferably, the delivery system is a nicotine delivery system which is provided in chewing gum form or lozenge form and which provides the nicotine in a transmucosally absorbable form. The two-stage medicine delivery system preferably releases a buffering agent which increases a pH level in a user's mouth to facilitate absorption of the medicine when the delivery system is placed in the user's mouth. A method of making the medicine delivery system also is provided. The system and apparatus can be adapted to reduce cravings for alcohol, food, drugs (e.g.Type: GrantFiled: March 18, 2002Date of Patent: May 17, 2005Assignee: JSR, LLCInventors: John M. Pinney, Jack E. Henningfield, Saul Shiffman, Joseph Gitchell, Edward J. Cone
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Publication number: 20020102304Abstract: A two-stage medicine delivery system provides an initial dose of medicine and a second dose of medicine. The initial and second doses are capable of achieving a rapid pharmacological effect and a prolonged pharmacological effect, respectively. The two-stage medicine delivery system preferably delivers a craving reduction substance, in which case, the rapid and prolonged pharmacological effects include a rapid and prolonged craving reduction. Preferably, the delivery system is a nicotine delivery system which is provided in chewing gum form or lozenge form and which provides the nicotine in a transmucosally absorbable form. The two-stage medicine delivery system preferably releases a buffering agent which increases a pH level in a user's mouth to facilitate absorption of the medicine when the delivery system is placed in the user's mouth. A method of making the medicine delivery system also is provided. The system and apparatus can be adapted to reduce cravings for alcohol, food, drugs (e.g.Type: ApplicationFiled: March 18, 2002Publication date: August 1, 2002Inventors: John M. Pinney, Jack E. Henningfield, Saul Shiffman, Joseph Gitchell, Edward J. Cone
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Publication number: 20020098264Abstract: A chewing gum delivery system has nicotine, gum base and a buffer system with an improved release rate for the nicotine. The resulting delivery system advantageously provides a convenient, reliable, practical, and relatively painless system for delivering an active. The delivery system is capable of delivering initial and second doses of a craving reduction active or other actives (e.g., nicotine), the combination of which rapidly reduces cravings, or provides some other pharmacological effect, and provides the pharmacological effect or protection from such cravings over a prolonged period of time beyond the initial dose. Notably, the delivery system is capable of rapidly achieving a pharmacologically effective concentration of the active (e.g., nicotine) in the bloodstream (e.g.Type: ApplicationFiled: February 1, 2002Publication date: July 25, 2002Inventors: Subraman R. Cherukuri, John M. Pinney, Jack E. Henningfield, Aradhana Sasan, Edward J. Cone, Saul Shiffman, Joe Gitchell, Carlos D. Malvestutto
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Patent number: 6358060Abstract: A two-stage medicine delivery system provides an initial dose of medicine and a second dose of medicine. The initial second doses are capable of achieving a rapid pharmacological effect and a prolonged pharmacological effect, respectively. The two-stage medicine delivery system preferably delivers a craving reduction substance, in which case, the rapid and prolonged pharmacological effects include a rapid and prolonged craving reduction. Preferably, the delivery system is a nicotine delivery system which is provided in chewing gum form or lozenge form and which provides the nicotine in a transmucosally absorbable form. The two-stage medicine delivery system preferably releases a buffering agent which increases a pH level in a user's mouth to facilitate absorption of the medicine when the delivery system is placed in the user's mouth. A method of making the medicine delivery system also is provided. The system and apparatus can be adapted to reduce cravings for alcohol, food, drugs (e.g.Type: GrantFiled: September 3, 1998Date of Patent: March 19, 2002Assignee: JSR LLCInventors: John M. Pinney, Jack E. Henningfield, Saul Shiffman, Joseph Gitchell, Edward J. Cone
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Publication number: 20020018800Abstract: A two-stage medicine delivery system provides an initial dose of medicine and a second dose of medicine. The initial and second doses are capable of achieving a rapid pharmacological effect and a prolonged pharmacological effect, respectively. The two-stage medicine delivery system preferably delivers a craving reduction substance, in which case, the rapid and prolonged pharmacological effects include a rapid and prolonged craving reduction. Preferably, the delivery system is a nicotine delivery system which is provided in chewing gum form or lozenge form and which provides the nicotine in a transmucosally absorbable form. The two-stage medicine delivery system preferably releases a buffering agent which increases a pH level in a user's mouth to facilitate absorption of the medicine when the delivery system is placed in the user's mouth. A method of making the medicine delivery system also is provided. The system and apparatus can be adapted to reduce cravings for alcohol, food, drugs (e.g.Type: ApplicationFiled: September 3, 1998Publication date: February 14, 2002Inventors: JOHN M. PINNEY, JACK E. HENNINGFIELD, SAUL SHIFFMAN, JOSEPH GITCHELL, EDWARD J. CONE
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Patent number: 6344222Abstract: A chewing gum delivery system has nicotine, gum base and a buffer system with an improved release rate for the nicotine. The resulting delivery system advantageously provides a convenient, reliable, practical, and relatively painless system for delivering an active. The delivery system is capable of delivering initial and second doses of a craving reduction active or other actives (e.g., nicotine), the combination of which rapidly reduces cravings, or provides some other pharmacological effect, and provides the pharmacological effect or protection from such cravings over a prolonged period of time beyond the initial dose. Notably, the delivery system is capable of rapidly achieving a pharmacologically effective concentration of the active (e.g., nicotine) in the bloodstream (e.g.Type: GrantFiled: September 2, 1999Date of Patent: February 5, 2002Assignee: JSR LLCInventors: Subraman R. Cherukuri, John M. Pinney, Jack E. Henningfield, Aradhana Sasan, Edward J. Cone, Saul Shiffman, Joe Gitchell, Carlos D. Malvestutto