Abstract: A non-degradable topical ocular drug delivery device includes about 0.001% to about 10% w/w of at least one myopia-suppressing agent complexed with an immobile acid within a crosslinked polymer matrix. The cross-linked polymer matrix is configured to deliver the least one myopia-suppressing agent over an extended period of time at a concentration and rate that controls myopia progression while preserving pupillary function and accommodation.

Abstract: Ophthalmic solutions are provided for use as tear substitutes and contact lens solutions. These solutions contain a cationic polymeric surfactant that has an affinity for the surface of the eye or a contact lens. Also disclosed are ophthalmic solutions containing a combination of the cationic polymeric surfactant and a water soluble anionic polymer which forms a complex in aqueous solution. The complex has an affinity for the surface of the eye or contact lens. In this manner, the present solutions provide improved duration of comfort to the user. The present compositions are also useful as carriers for ophthalmic drugs.

Abstract: A non-degradable topical ocular drug delivery device includes about 0.001% to about 10% w/w of at least one myopia-suppressing agent complexed with an immobile acid within a crosslinked polymer matrix. The cross-linked polymer matrix is configured to deliver the least one myopia-suppressing agent over an extended period of time at a concentration and rate that controls myopia progression while preserving pupillary function and accommodation.

Abstract: A method for forming an ocular drug delivery device includes the steps of: (1) forming a drug core containing an active agent, wherein the drug core has a barrier disposed all surfaces thereof except for a drug release surface which is left free of the barrier; (2) forming a drug release membrane over the drug release surface; and (3) forming the remaining portion of the device body by an overcast (overmold) process.

Abstract: A method for forming an ocular drug delivery device includes the steps of: (1) forming a drug core containing an active agent, wherein the drug core has a barrier disposed all surfaces thereof except for a drug release surface which is left free of the barrier; (2) forming a drug release membrane over the drug release surface; and (3) forming the remaining portion of the device body by an overcast (overmold) process.

Abstract: A device is disclosed for delivering an active agent to target tissue at a site that includes a bodily fluid. The device includes a body that has an erodible member that releases the active agent over a prescribed period of time.

Abstract: Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises hollow micro particles cohered to a mass by a combination of low and high molecular weight thermoplastic bonding agents. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical or vehicular cushions, positioning devices, mattresses impact protective padding and the like.

Abstract: Polymeric compositions containing a high percentage of bound polypropylene glycol provide matrices for the controlled release of drugs and medicinal agents. The compositions are prepared by the polymerization of ethylenically unsaturated polypropylene glycol containing monomers. Copolymers of ethylenically unsaturated polypropylene glycol containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility as ocular insets for the controlled release of drug(s) into the eye.

Abstract: The present invention relates to an aqueous formulation to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a glycoprotein component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the glycoproteins are derived from mammalian milk, preferably bovine.

Abstract: The present invention relates to an aqueous formulation to be instilled into the eye, or in which to pre soak or store an object to be inserted into the eye, such as a contact lens, an ointment, or a solid device to be inserted into the conjunctival sac. The preparations disclosed are utilized for the treatment of a tear film and ocular surface disorder known as keratoconjunctivitis sicca or dry eye syndrome. In general, the preparations of this invention are also effective for the relief of symptoms of eye irritation, such as those caused by dry environmental conditions or by contact lens wear. In accordance with the present invention, the ophthalmic preparation includes a glycomacropeptide component, similar to that found at the normal human ocular surface and in one exemplary and preferred embodiment, the glycomacropeptide is derived from mammalian milk, preferably bovine.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises a liquid or semi-solid matrix phase and an expanded Perlite included phase. The material is useful for providing low weight contour conforming resilent padding for garments, athletic equipment, prosthetic devices, surgical, medical or vehicular cushions, positioning devices, mattresses, impact protective padding and the like.

Abstract: An apparatus for wrapping hair with a cord is provided and includes a housing; a main spindle operatively coupled to the housing and defining a main spindle bore for receiving cord and hair; a rotatable spool carrier and at least one spool. The spool carrier has a platform and a drive spindle operatively coupled to the main spindle so that rotation of the main spindle is translated into rotation of the platform. The drive spindle has guides for receiving cord and permitting the cord to be disposed through a bore extending through the drive spindle. The rotation of the main spindle causes cord to be dispensed through the one guide and the drive spindle bore and the main spindle bore, hair is disposed through the drive spindle bore and the main spindle bore, and the main spindle is rotated to wrap the hair with cord.

Abstract: An apparatus for wrapping hair with a cord is provided and includes a housing; a main spindle operatively coupled to the housing and defining a main spindle bore for receiving cord and hair; a rotatable spool carrier and at least one spool. The spool carrier has a platform and a drive spindle operatively coupled to the main spindle so that rotation of the main spindle is translated into rotation of the platform. The drive spindle has guides for receiving cord and permitting the cord to be disposed through a bore extending through the drive spindle. The rotation of the main spindle causes cord to be dispensed through the one guide and the drive spindle bore and the main spindle bore, hair is disposed through the drive spindle bore and the main spindle bore, and the main spindle is rotated to wrap the hair with cord.

Abstract: An apparatus for wrapping hair with a cord is provided and according to one embodiment includes a housing; a main spindle operatively coupled to the housing and one or more cartridges with one cartridge being operatively coupled to the main spindle and the other cartridges being operatively coupled to one another. Each cartridge contains a cord that is dispensed and wrapped around hair as a result of the rotation of the main spindle.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises a liquid or semi-solid matrix phase and an expanded Perlite included phase. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical, medical or vehicular cushions, positioning devices, mattresses, impact protective padding and the like.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises hollow coated micro particles cohered to a mass by a combination of a carboxylic acid bonding agent and a hydrophobic fluid. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical or vehicular cushions, positioning devices, mattresses impact protective padding and the like.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises hollow coated micro particles cohered to a mass by a combination of a carboxylic acid bonding agent and a hydrophobic fluid. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical or vehicular cushions, positioning devices, mattresses impact protective padding and the like.

Abstract: The present invention is based on the unexpected finding that the combination of a carboxylate containing anionic polymer, of molecular weight greater than about 1000 daltons, with cleaning agents, provides improved contact lens cleaning preparations. The present invention includes contacting a soiled contact lens with an aqueous solution comprising an anionically charged polymer and a surfactant or surfactant combination selected from the classes of nonionic surfactants, anionic surfactants, and amphoteric surfactants.

Abstract: An improved material for use in resilient conforming pads, cushions, impact resistance padding and the like is described. The material comprises hollow micro particles cohered to a mass by a combination of low and high molecular weight thermoplastic bonding agents. The material is useful for providing low weight contour conforming resilient padding for garments, athletic equipment, prosthetic devices, surgical or vehicular cushions, positioning devices, mattresses impact protective padding and the like.