Patents by Inventor Edward J. Holland

Edward J. Holland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240366840
    Abstract: A technique can consistently achieve thicknesses of ?50 ?m for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ?50 ?m are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ?100 ?m, or more particularly ?50 ?m, to produce a corneal graft.
    Type: Application
    Filed: May 10, 2024
    Publication date: November 7, 2024
    Applicant: CorneaGen
    Inventors: Edward J. Holland, Kevin Potts, Timothy G. Baldwin
  • Patent number: 12016970
    Abstract: A technique can consistently achieve thicknesses of ?50 ?m for corneal tissue for for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ?50 ?m are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the precut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ?100 ?m, or more particularly ?50 ?m, to produce a corneal graft.
    Type: Grant
    Filed: November 29, 2022
    Date of Patent: June 25, 2024
    Assignee: CorneaGen Inc.
    Inventors: Edward J. Holland, Kevin Potts, Timothy G. Baldwin
  • Publication number: 20230097900
    Abstract: A technique can consistently achieve thicknesses of ? 50 µm for corneal tissue for for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ? 50 µm are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the precut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ? 100 µm, or more particularly ? 50 µm, to produce a corneal graft.
    Type: Application
    Filed: November 29, 2022
    Publication date: March 30, 2023
    Inventors: Edward J. Holland, Kevin Potts, Timothy G. Baldwin
  • Patent number: 11547778
    Abstract: A technique can consistently achieve thicknesses of ?50 ?m for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ?50 ?m are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ?100 ?m, or more particularly ?50 ?m, to produce a corneal graft.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: January 10, 2023
    Assignee: CORNEAGEN INC.
    Inventors: Edward J. Holland, Kevin Potts, Timothy G. Baldwin
  • Publication number: 20200268941
    Abstract: A technique can consistently achieve thicknesses of ?50 ?m for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ?50 ?m are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ?100 ?m, or more particularly ?50 ?m, to produce a corneal graft.
    Type: Application
    Filed: February 25, 2020
    Publication date: August 27, 2020
    Inventors: Edward J. Holland, Kevin Potts, Timothy G. Baldwin