Patents by Inventor Edward J. Macarak

Edward J. Macarak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5776914
    Abstract: Disclosed are compositions and methods for preventing or substantially inhibiting the hemolytic activity of hemolysis inducing agents. The methods and compositions are based on the use of an anionic oligosaccharide, such as polysulfated cyclodextrin, to achieve the desired reduction in hemolytic active inducing agents.
    Type: Grant
    Filed: November 30, 1994
    Date of Patent: July 7, 1998
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Paul B. Weisz, Edward J. Macarak
  • Patent number: 5446030
    Abstract: Disclosed are compositions and methods for prevented or substantially inhibiting the hemolytic activity of hemolysis inducing agents. The methods and compositions are based on the use an anionic oligosaccharide, such as polysulfated cyclodextrin, to achieve the desired reduction in hemolytic active inducing agents.
    Type: Grant
    Filed: September 19, 1991
    Date of Patent: August 29, 1995
    Inventors: Paul B. Weisz, Edward J. Macarak
  • Patent number: 4851354
    Abstract: An apparatus useful for studying cells in culture under conditions which reproduce their natural, in vivo mechanical environment is disclosed. The device comprises an airtight well having an optically transparent compliant base of a biologically compatible material on which said cells may be grown and an optically transparent, removable cap, coupled with a ported, airtight reservoir which reservoir has an optically transparent base and which reservoir can be filled with pressurizing media to create cyclic variations in hydrostatic pressure beneath said compliant base, causing said compliant base to deform and thereby exert a substantially uniform biaxial strain on the cells attached thereto.
    Type: Grant
    Filed: December 7, 1987
    Date of Patent: July 25, 1989
    Assignee: Trustees of the University of Pennsylvania
    Inventors: Flaura K. Winston, Lawrence E. Thibault, Edward J. Macarak