Patents by Inventor Edward J. Marsh

Edward J. Marsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified thermostable pyrococcus furiosus DNA ligase
    Patent number: 6280998
    Abstract: Purified thermostable DNA ligase is described that catalyzes template-dependent ligation at temperatures of about 30° C. to about 80° C., and which substantially retains its catalytic ability when subjected to temperatures of from about 85° C. to about 100° C. The thermostable DNA ligase has an estimated molecular weight of 50,000 to 70,000 daltons. A preferred thermostable DNA ligase is described that was isolated from the archaebacteria Pyrococcus furiosus. Also described are plasmid vectors for producing recombinant thermostable DNA ligase.
    Type: Grant
    Filed: August 22, 1997
    Date of Patent: August 28, 2001
    Assignee: Stratagene
    Inventors: Eric J. Mathur, Edward J. Marsh, Warren E. Schoettlin
  • Purified thermostable pyrococcus furiousus DNA ligase
    Patent number: 5700672
    Abstract: Purified thermostable DNA ligase is described that catalyzes template-dependent ligation at temperatures of about 30.degree. C. to about 80.degree. C., and which substantially retains its catalytic ability when subjected to temperatures of from about 85.degree. C. to about 100.degree. C. The thermostable DNA ligase has an estimated molecular weight of 50,000 to 70,000 daltons. A preferred thermostable DNA ligase is described that was isolated from the archaebacteria Pyrococcus furiosus. Also described are plasmid vectors for producing recombinant thermostable DNA ligase.
    Type: Grant
    Filed: July 23, 1992
    Date of Patent: December 23, 1997
    Assignee: Stratagene
    Inventors: Eric J. Mathur, Edward J. Marsh, Warren E. Schoettlin
  • Purified thermostable Pyrococcus furiosus DNA ligase
    Patent number: 5506137
    Abstract: Purified thermostable DNA ligase is described that catalyzes template-dependent ligation at temperatures of about 30.degree. C. to about 80.degree. C., and which substantially retains its catalytic ability when subjected to temperatures of from about 85.degree. C. to about 100.degree. C. The thermostable DNA ligase has an estimated molecular weight of 50,000 to 70,000 daltons. A preferred thermostable DNA ligase is described that was isolated from the archaebacteria Pyrococcus furiosus. Also described are plasmid vectors for producing recombinant thermostable DNA ligase.
    Type: Grant
    Filed: July 22, 1993
    Date of Patent: April 9, 1996
    Assignee: Stratagene
    Inventors: Eric J. Mathur, Edward J. Marsh, Warren E. Schoettlin