Patents by Inventor Edward J. Roy

Edward J. Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of folate anti-effector cell antibodies
    Patent number: 5547668
    Abstract: The present invention provides a process of targeting folate-receptor-positive tumor cells for lysis by binding a conjugate of folate and an anti-T-cell-receptor antibody or an anti-Fc receptor antibody to those cells. A process of lysing folate-receptor-positive tumor cells comprising exposing the cells to a folate/anti-T-cell-receptor antibody in the presence of a population of T-cells is also provided. A process of lysing folate-receptor-positive tumor cells comprising exposing the cells to a folate/anti-Fc receptor antibody in the presence of a population of natural killer cells, monocytes, or macrophages is also provided. Still further, the present invention provides a conjugate of folate to an anti-T-cell-receptor antibody or an anti-Fc receptor antibody.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: August 20, 1996
    Assignee: The Board of Trustees of The University of Illinois
    Inventors: David M. Kranz, Edward J. Roy, Todd A. Patrick