Patents by Inventor Edward J. Victoria

Edward J. Victoria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic and diagnostic domain 1 ?2GPI polypeptides and methods of using same
    Patent number: 6858210
    Abstract: The present invention provides domain 1 ?2GPI polypeptides, polynucleotides encoding these polypeptides, mimetics of these polypeptides, and methods using domain 1 ?2GPI polypeptides and mimetics. Domain 1 of ?2GPI has been shown to bind to anti-cardiolipin (?2GPI-dependent antiphospholipid) antibodies, which are associated with several pathologies, such as thrombosis and fetal loss. The domain 1 ?2GPI polypeptides may be used to detect ?2GPI-dependent antiphospholipid antibodies in a sample. The invention further provides methods of inducing tolerance using these domain 1 ?2GPI polypeptides.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: February 22, 2005
    Assignee: La Jolla Pharmaceutical Co.
    Inventors: David M. Marquis, Gilbert M. Iverson, Edward J. Victoria, David S. Jones, Matthew D. Linnik