Abstract: An advanced tool drive system (ATDS) is capable of grasping a variety of tools through a common interface and provides multiple modes of operation for these tools for these tools. The ATDS is a combination of both a tool actuator and tool change-out mechanism and provides three nested drive actuators-two rotary and one linear. In addition to the tool drive, the ATDS includes four brushless direct current (BLDC) motors which provide the actuation torque to accomplish the multiple modes of ATDS operation, and a camera positioning mechanism (CPM) capable of viewing features on a client satellite or asteroid. By consolidating the drive actuation motors within the ATDS, the design of mating tools becomes less complex and reduces risk and cost of multiple drive actuators having to be installed in multiple tools.

Abstract: A toilet splash shield apparatus for preventing the splashing of urine includes a pair of shields comprising a left shield and a right shield. Each shield comprises a lower connector strip having a lower top side, a lower bottom side, a lower outer edge, a lower inner edge, a lower front edge, and a lower back edge. An upper connector strip has an upper top side, an upper bottom side, an upper outer edge, an upper inner edge, an upper front edge, and an upper back. A plurality of lower engagement members is coupled to the lower connector strip to selectively engage a rim of a toilet. A plurality of upper engagement members is coupled to the upper connector strip to selectively engage a seat underside of a seat of the toilet. A shield body is coupled to the lower connector strip and the upper connector strip and is foldable.

Abstract: Compounds of general formula (I): (Formula I)) wherein R1, Q, R3, R4, R5, R6, R7 and Ar1 are as defined herein are inhibitors of class I histone deacetylases and are of use in the treatment of lysosomal storage disorders, especially Niemann-Pick type C disease, as well as other lysosomal storage disorders, defective autophagy, accumulation of free cholesterol and mycobacterial diseases.

Abstract: Compounds of general formula (I): (Formula I)) wherein R1, Q, R3, R4, R5, R6, R7 and Ar1 are as defined herein are inhibitors of class I histone deacetylases and are of use in the treatment of lysosomal storage disorders, especially Niemann-Pick type C disease, as well as other lysosomal storage disorders, defective autophagy, accumulation of free cholesterol and mycobacterial diseases.

Abstract: An electron energy loss spectrometer is described having a direct detection sensor, a high speed shutter and a sensor processor wherein the sensor processor combines images from individual sensor read-outs and converts a two dimensional image from said sensor into a one dimensional spectrum and wherein the one dimensional spectrum is output to a computer and operation of the high speed shutter is integrated with timing of imaging the sensor. The shutter is controlled to allow reduction in exposure of images corresponding to the individual sensor readouts. A plurality of images are exposed by imaging less than the full possible exposure and wherein the plurality of images are combined to form a composite image. The plurality of images can be comprised of images created by exposing the sensor for different exposure times.

Abstract: An electron energy loss spectrometer is described having a direct detection sensor, a high speed shutter and a sensor processor wherein the sensor processor combines images from individual sensor read-outs and converts a two dimensional image from said sensor into a one dimensional spectrum and wherein the one dimensional spectrum is output to a computer and operation of the high speed shutter is integrated with timing of imaging the sensor. The shutter is controlled to allow reduction in exposure of images corresponding to the individual sensor readouts. A plurality of images are exposed by imaging less than the full possible exposure and wherein the plurality of images are combined to form a composite image. The plurality of images can be comprised of images created by exposing the sensor for different exposure times.

Abstract: An electron energy loss spectrometer is described having a direct detection sensor, a high speed shutter and a sensor processor wherein the sensor processor combines images from individual sensor read-outs and converts a two dimensional image from said sensor into a one dimensional spectrum and wherein the one dimensional spectrum is output to a computer and operation of the high speed shutter is integrated with timing of imaging the sensor. The shutter is controlled to allow reduction in exposure of images corresponding to the individual sensor readouts. A plurality of images are exposed by imaging less than the full possible exposure and wherein the plurality of images are combined to form a composite image. The plurality of images can be comprised of images created by exposing the sensor for different exposure times.

Abstract: An electron energy loss spectrometer is described having a direct detection sensor, a high speed shutter and a sensor processor wherein the sensor processor combines images from individual sensor read-outs and converts a two dimensional image from said sensor into a one dimensional spectrum and wherein the one dimensional spectrum is output to a computer and operation of the high speed shutter is integrated with timing of imaging the sensor. The shutter is controlled to allow reduction in exposure of images corresponding to the individual sensor readouts. A plurality of images are exposed by imaging less than the full possible exposure and wherein the plurality of images are combined to form a composite image. The plurality of images can be comprised of images created by exposing the sensor for different exposure times.

Abstract: A smart network may include a smart network host device as well as one or more client devices configured to connect to the smart network. Each of the client devices may implement one or more services that the client device exposes to other devices connected to the smart network. A client device configured to connect to the smart network may implement one or more modules configured to facilitate connecting to the smart network, registering the client device or services running on the client device with the smart network, diagnosing issues with the client device or the smart network, and upgrading the firmware of the client device. The client device may be configured to perform the various operations with minimal input from an owner of the smart network.

Abstract: A smart network may include a smart network host device as well as one or more client devices configured to connect to the smart network. Each of the client devices may implement one or more services that the client device exposes to other devices connected to the smart network. Each of the client devices includes network layer 2 and 3 attributes as well as network layer 7 application attributes. The application attributes are enumerated as named services, which each client device registers with the smart network host device. When a client device needs access to a named service, the smart network host device uses layer 2, 3, and 7 attributes associated with the client device to select a suitable server for providing the named service to the client device.

Abstract: A smart network may include a smart network host device as well as one or more client devices configured to connect to the smart network. Each of the client devices may implement one or more services that the client device exposes to other devices connected to the smart network. Each of the client devices includes network layer 2 and 3 attributes as well as network layer 7 application attributes. The application attributes are enumerated as named services, which each client device registers with the smart network host device. When a client device needs access to a named service, the smart network host device uses layer 2, 3, and 7 attributes associated with the client device to select a suitable server for providing the named service to the client device.

Abstract: A smart network may include a smart network host device as well as one or more client devices configured to connect to the smart network. Each of the client devices may implement one or more services that the client device exposes to other devices connected to the smart network. A client device configured to connect to the smart network may implement one or more modules configured to facilitate connecting to the smart network, registering the client device or services running on the client device with the smart network, diagnosing issues with the client device or the smart network, and upgrading the firmware of the client device. The client device may be configured to perform the various operations with minimal input from an owner of the smart network.