Abstract: A method of fusing a sacroiliac joint including: a) approaching a posterior aspect of a sacroiliac joint space with a joint implant including a body extending a length between a distal end and a proximal end; and b) delivering the joint implant into the sacroiliac joint space such that the joint implant passes through an access region defined between a posterior superior iliac spine and a posterior inferior iliac spine, the joint implant being oriented in the sacroiliac joint space such that a portion of the body of the joint implant is positioned within a joint plane of the sacroiliac joint space, and such that the distal end of the joint implant is positioned posteriorly of an anterior boundary of the sacroiliac joint space.

Abstract: A method of fusing a sacroiliac joint including a sacrum, an ilium, and a sacroiliac joint space defined therebetween. The method may include: approaching a posterior aspect of the sacroiliac joint space with a joint implant including a body extending a length between a distal end and a proximal end; and delivering the joint implant into the sacroiliac joint space such that the joint implant passes through an access region defined between the posterior superior iliac spine and the posterior inferior iliac spine. The joint implant may be oriented in the sacroiliac joint space such that a portion of the body of the joint implant is positioned within a joint plane of the sacroiliac joint space, and such that the distal end of the joint implant is positioned posteriorly of an anterior boundary of the sacroiliac joint space.

Abstract: An orthopedic anchoring system for attaching a spinal stabilization system and concomitantly fusing a sacroiliac joint is disclosed that includes a delivery tool and an implant assembly for insertion into a joint space of a sacroiliac joint. The implant assembly may be secured using anchors inserted through bores within the implant body and into the underlying sacrum and/or ilium. The implant body may also include an attachment fitting reversibly attached to a guide to provide attachment fittings for elements of the spinal stabilization system. The implant assembly may be releasably coupled to an implant arm of the delivery tool such that the implant arm is substantially aligned with the insertion element of the implant assembly. An anchor arm used to insert the anchor may be coupled to the implant arm in a fixed and nonadjustable arrangement such that the anchor is generally aligned with a bore within the implant assembly.

Abstract: A system for performing a fusion procedure on a sacroiliac joint defined between a sacrum and an ilium. The system may include a working cannula including a proximal end, a distal end, a tubular body extending between the proximal and distal ends, a cannula passageway defined within the tubular body and having a cannula axis extending there through, a pair of prongs coupled to the tubular body and extending distally there from, an anchor arm engagement structure coupled to the tubular body, and a pin guide coupled to the tubular body and defining a pin passageway having a guidance axis there through that is generally parallel with the cannula axis.

Abstract: A method of fusing a sacroiliac joint including implanting a joint implant into the sacroiliac joint such that the joint implant passes through a cranial access region, the joint implant having an implanted position in the sacroiliac joint such that a portion of a body of the joint implant is positioned within a cranial portion of the sacroiliac joint.

Abstract: A spinal stabilization system is provided for maintaining preselected spacing and movement between adjacent vertebrae in a spinal column and for providing overall stability thereto. The system includes interlaminar members positioned in the spaces intermediate a first vertebra and the vertebrae positioned immediately above and immediately below and adjacent to the first vertebra. The interlaminar members are operatively connected to one another by an adjustable support structure and cooperate therewith to maintain the preselected spacing between adjacent vertebrae and to provide overall stability to the spinal column.

Abstract: A method for fixating a dysfunctional sacroiliac joint including implanting a joint implant at the sacroiliac joint. The joint implant may include: a length extending between a proximal end and a distal end; an exterior surface extending the length; an interior surface opposite the exterior surface and extending the length, the interior surface defining an internal volume therein; a wall thickness defined between the external surface and the interior surface; a proximal opening extending into the internal volume; a first wall section comprising a first plurality of struts arranged along the length and defining a first plurality of openings extending through the wall thickness; and a second wall section including a second plurality of struts arranged along the length and defining a second plurality of opening extending through the wall thickness. Each opening of the first and second plurality of openings may be generally polygonal in shape.

Abstract: A method for fixating a dysfunctional sacroiliac joint for SI joint fusion including implanting a joint implant at the sacroiliac joint. The joint implant may include a body extending a length between a proximal end and a distal end, an exterior surface, an interior surface opposite the exterior surface and defining an internal volume therein, a wall thickness extending between the exterior surface and the interior surface, a proximal opening extending into the internal volume, and a first plurality of voids along the length and extending through the wall thickness from the exterior surface to the interior surface. The first plurality of voids may be arranged along the length in a repeating pattern of a group of voids, wherein each void of the first plurality of voids is generally polygonal in shape.

Abstract: A method for preparing a sacroiliac joint for stabilization which may include approaching a posterior aspect of the sacroiliac joint inferior to a PSIS with a defect-creating tool assembly, creating a defect in the sacrum and the ilium defined by at least one noncircular cross-sectional shape, delivering an implant having a body with a length extending between proximal and distal ends, the body including at least one cylindrical body with a longitudinal axis and an opening at the proximal end aligned with the longitudinal axis of the cylindrical body, a pattern of openings spaced along the cylindrical body and a planar member coupled with and extending along the cylindrical body. The implant may be implanted with the length generally following a plane of the sacroiliac joint such that it is advanced from a generally posterior to anterior approach while the body of the implant bridges the joint.

Abstract: A sacroiliac joint fusion system that provides a method of fixation and fusion of the sacroiliac joint and sacroiliac fixation fusion implant which upon placement facilitates stability and fusion of the sacroiliac joint.

Abstract: The present disclosure provides inventive cosmetic/dermatological formulations and/or preparations that include mesenchymal stem cells (MSCs), and also provides associated methods for repairing, rejuvenating and/or augmenting skin tissue. The formulations and/or preparations include MSCs that are formulated into creams, lotions, and the like. In one aspect, the MSCs are obtained autogenously. In another aspect, the MSCs are obtained from allogeneic sources. In another aspect, the MSCs may be minimally manipulated. In another aspect, the MSCs may be derived from bone marrow or adipose tissue. In another aspect, the MSCs can be utilized from bone marrow concentrate (BMC) or from adipose stromal vascular fraction (SVF). In another aspect, the MSCs can also be utilized after cell expansion. The associated methods comprise topical application of the cosmetic/dermatological formulations and/or preparations onto skin tissue, resulting in repairing, rejuvenating, and/or augmenting the skin tissue.

Abstract: A method of fusing a sacroiliac joint including a sacrum, an ilium, and a sacroiliac joint space defined therebetween. The method may include: approaching a posterior aspect of the sacroiliac joint space with a joint implant including a body extending a length between a distal end and a proximal end; and delivering the joint implant into the sacroiliac joint space such that the joint implant passes through an access region defined between the posterior superior iliac spine and the posterior inferior iliac spine. The joint implant may be oriented in the sacroiliac joint space such that a portion of the body of the joint implant is positioned within a joint plane of the sacroiliac joint space, and such that the distal end of the joint implant is positioned posteriorly of an anterior boundary of the sacroiliac joint space.

Abstract: A method for fixating a dysfunctional sacroiliac joint for SI joint fusion including implanting a joint implant at the sacroiliac joint. The joint implant may include a body extending a length between a proximal end and a distal end, an exterior surface, an interior surface opposite the exterior surface and defining an internal volume therein, a wall thickness extending between the exterior surface and the interior surface, a proximal opening extending into the internal volume, and a first plurality of voids along the length and extending through the wall thickness from the exterior surface to the interior surface. The first plurality of voids may be arranged along the length in a repeating pattern of a group of voids, wherein each void of the first plurality of voids is generally polygonal in shape.

Abstract: A method for fixating a dysfunctional sacroiliac joint including implanting a joint implant at the sacroiliac joint. The joint implant may include: a length extending between a proximal end and a distal end; an exterior surface extending the length; an interior surface opposite the exterior surface and extending the length, the interior surface defining an internal volume therein; a wall thickness defined between the external surface and the interior surface; a proximal opening extending into the internal volume; a first wall section comprising a first plurality of struts arranged along the length and defining a first plurality of openings extending through the wall thickness; and a second wall section including a second plurality of struts arranged along the length and defining a second plurality of opening extending through the wall thickness. Each opening of the first and second plurality of openings may be generally polygonal in shape.

Abstract: A method of fusing a sacroiliac joint including delivering a joint fixation screw into engagement with the sacroiliac joint, the screw having either: 1) a body including helical spiral threads, an anti-migration surface feature including at least one ridge extending distally from the proximal end at least partially the length, and a plurality of openings extending into the body; or 2) a body including a hollow interior, helical spiral threads and a plurality of openings extending into the hollow interior, wherein the helical spiral threads have a thread cross-section including: a height extending between a connection point with the body and a radial termination, a first thickness at the radial termination extending between opposite thread walls, and a second thickness located between the connection point and the radial termination extending between opposite thread walls, the first thickness being substantially greater the second thickness.

Abstract: A method of fusing a sacroiliac joint including delivering a screw across the sacroiliac joint and into the sacrum and the ilium, the screw including a body having helical spiral threads and spiral flutes extending into the body of the screw.

Abstract: A system for fixating a dysfunctional sacroiliac joint for SI joint fusion, the system including a sacroiliac joint implant and a delivery tool configured for approaching a sacroiliac joint. The system may include an implant having a porous 3D matrix structure and may be manufactured by laser or electron beam additive manufacturing. The delivery tool may include a radiolucent material. The SI fusion system may further include custom sacroiliac joint implants, anchors, alignment tools or targeting arms manufactured for a particular patient. Pre-surgical imaging studies, including 3D rendering, and their interpretation may assist in planning desired trajectories, anchor dimensions and implant dimensions and may provide details specific to the manufacture of particular sacroiliac joint tools or implants and their implantation into the sacroiliac joint. The system may be configured for use with surgical robots and may include an integrated nerve monitoring and stimulation system.

Abstract: A sacroiliac joint fusion system including a joint implant, anchor element and delivery tool. The joint implant includes a bore extending non-parallel to the implant longitudinal axis. The anchor element is for receiving in the bore. The delivery tool includes an implant arm and anchor arm. The implant arm distal end is releasably coupled to the joint implant proximal end so the implant arm longitudinal axis is coaxial or parallel with the implant body longitudinal axis. An anchor arm distal end is engaged to the anchor element proximal end. The anchor arm is coupled to the implant arm such that the anchor element longitudinal axis is coaxially aligned with the bore longitudinal axis when the implant arm distal end is releasably coupled with the implant proximal end and the anchor arm distal end is engaged with the anchor element proximal end.

Abstract: A method of fusing a sacroiliac joint including delivering a screw across the sacroiliac joint and into the sacrum and the ilium, the screw including a body having helical spiral threads and spiral flutes extending into the body of the screw.

Abstract: A method of fusing a sacroiliac joint including delivering a joint fixation screw into engagement with the sacroiliac joint, the screw having either: 1) a body including helical spiral threads, an anti-migration surface feature including at least one ridge extending distally from the proximal end at least partially the length, and a plurality of openings extending into the body; or 2) a body including a hollow interior, helical spiral threads and a plurality of openings extending into the hollow interior, wherein the helical spiral threads have a thread cross-section including: a height extending between a connection point with the body and a radial termination, a first thickness at the radial termination extending between opposite thread walls, and a second thickness located between the connection point and the radial termination extending between opposite thread walls, the first thickness being substantially greater the second thickness.